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Biology and Biochemistry

D-Index
65
Citations
20991
World Ranking
8993
National Ranking
3996

Overview

Kathleen D. Danenberg is affiliated with the University of Southern California in the United States and has contributed to research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields, including Oncology, Cancer Research, Pulmonary and Respiratory Medicine, Molecular Biology, and Pathology and Forensic Medicine.

The research focus includes topics such as Colorectal Cancer Treatments and Studies, Cancer Genomics and Diagnostics, Cancer-related molecular mechanisms research, RNA modifications and cancer, Lung Cancer Treatments and Mutations, Genetic factors in colorectal cancer, and Colorectal Cancer Surgical Treatments.

Recent publications by Kathleen D. Danenberg include:

  • Dynamic changes in RAS gene status in circulating tumour DNA: a phase II trial of first-line FOLFOXIRI plus bevacizumab for RAS-mutant metastatic colorectal cancer (2022) published in ESMO Open
  • Using cfRNA as a tool to evaluate clinical treatment outcomes in patients with metastatic lung cancers and other tumors (2021) published in Cancer Drug Resistance
  • P14.04 cfRNA from Liquid Biopsies Is More Abundant Than cfDNA, Informs Treatment Outcome and Is Concordant with Tissue (2021) published in Journal of Thoracic Oncology
  • Patient-centered developments in colon- and rectal cancer with a multidisciplinary international team: From translational research to national guidelines (2021) published in World Journal of Gastrointestinal Surgery
  • P15.04 A Phase I/IB Trial of Pembrolizumab and Trametinib Focused on Advanced KRAS Mutant Non-Small Cell Lung Cancer (2021) published in Journal of Thoracic Oncology

Kathleen D. Danenberg has collaborated frequently with coauthors including Yu Sunakawa, J. Usher, P. V. Danenberg, Luis E. Raez, and Daniel Sumarriva.

The scientist's publications have appeared most often in Journal of Thoracic Oncology, alongside other venues such as ESMO Open, Cancer Drug Resistance, World Journal of Gastrointestinal Surgery, and Cancer Medicine.

Best Publications

  • MethyLight: a high-throughput assay to measure DNA methylation

    Cindy A. Eads;Kathleen D. Danenberg;Kazuyuki Kawakami;Leonard B. Saltz

  • Epidermal Growth Factor Receptor Gene and Protein and Gefitinib Sensitivity in Non–Small-Cell Lung Cancer

    Federico Cappuzzo;Fred R. Hirsch;Elisa Rossi;Stefania Bartolini

  • Colorectal Tumors Responding to 5-Fluorouracil Have Low Gene Expression Levels of Dihydropyrimidine Dehydrogenase, Thymidylate Synthase, and Thymidine Phosphorylase

    Dennis Salonga;Kathleen D. Danenberg;Martin Johnson;Ralf Metzger

  • Thymidylate Synthase Gene and Protein Expression Correlate and Are Associated with Response to 5-Fluorouracil in Human Colorectal and Gastric Tumors

    Patrick G. Johnston;Heinz-Josef Lenz;Cynthia G. Leichman;Kathleen D. Danenberg

  • ERCC1 and Thymidylate Synthase mRNA Levels Predict Survival for Colorectal Cancer Patients Receiving Combination Oxaliplatin and Fluorouracil Chemotherapy

    Yoshinori Shirota;Jan Stoehlmacher;Jan Brabender;Yi-Ping Xiong

  • ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy.

    Ralf Metzger;Cynthia Gail Leichman;Kathleen D. Danenberg;Peter V. Danenberg

  • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin.

    Cynthia Gail Leichman;Heinz-Josef Lenz;Lawrence Leichman;Kathleen Danenberg

  • Epidermal Growth Factor Receptor and HER2-neu mRNA Expression in Non-Small Cell Lung Cancer Is Correlated with Survival

    Jan Brabender;Kathleen D. Danenberg;Ralf Metzger;Paul M. Schneider

  • CpG Island Hypermethylation in Human Colorectal Tumors Is Not Associated with DNA Methyltransferase Overexpression

    Cindy A. Eads;Kathleen D. Danenberg;Kazuyuki Kawakami;Leonard B. Saltz

  • Ribonucleotide Reductase Messenger RNA Expression and Survival in Gemcitabine/Cisplatin-Treated Advanced Non-Small Cell Lung Cancer Patients

    Rafael Rosell;Kathleen D. Danenberg;Vincente Alberola;Gerold Bepler

  • ERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabine

    P. Ceppi;M. Volante;S. Novello;I. Rapa

  • Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival.

    Heinz-Josef Lenz;Cynthia Gail Leichman;Kathleen D. Danenberg;Peter V. Danenberg

  • An In vivo Platform for Translational Drug Development in Pancreatic Cancer

    Belen Rubio-Viqueira;Antonio Jimeno;George Cusatis;Xianfeng Zhang

  • NAD(P)H:quinone Oxidoreductase Gene Expression in Human Colon Carcinoma Cells: Characterization of a Mutation Which Modulates DT-diaphorase Activity and Mitomycin Sensitivity

    Robert D. Traver;Tetsuro Horikoshi;Kathleen D. Danenberg;Thomas H. W. Stadlbauer

  • Hypermethylated APC DNA in Plasma and Prognosis of Patients With Esophageal Adenocarcinoma

    Kazuyuki Kawakami;Jan Brabender;Reginald V. Lord;Susan Groshen

  • Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma.

    Cindy A. Eads;Reginald V. Lord;Soudamini K. Kurumboor;Kumari Wickramasinghe

  • ΔΙΑΔΙΚΑΣΙΑ ΥΨΗΛΗΣ ΠΑΡΟΧΗΣ ΓΙΑ ΑΝΑΛΥΣΗ ΜΕΘΥΛΙΩΣΗΣ DNA

    Laird Peter W;Carroll Cindy A;Danenberg Kathleen D

  • Molecular Determinants of Cetuximab Efficacy

    Daniel Vallböhmer;Wu Zhang;Michael Gordon;Dong Yun Yang

  • Different Lengths of a Polymorphic Repeat Sequence in the Thymidylate Synthase Gene Affect Translational Efficiency but Not Its Gene Expression

    Kazuyuki Kawakami;Dennis Salonga;Ji Min Park;Kathleen D. Danenberg

  • Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer.

    Rafael Rosell;Giorgio Scagliotti;Kathleen D. Danenberg;Reginald V N Lord

Frequent Co-Authors

Peter V. Danenberg
Peter V. Danenberg University of Southern California
Heinz-Josef Lenz
Heinz-Josef Lenz University of Southern California
Tom R. DeMeester
Tom R. DeMeester University of Southern California
Susan Groshen
Susan Groshen University of Southern California
Peter W. Laird
Peter W. Laird Van Andel Institute
Jeffrey A. Hagen
Jeffrey A. Hagen University of Southern California
Jeffrey H. Peters
Jeffrey H. Peters University Hospitals of Cleveland
David R. Gandara
David R. Gandara University of California, Davis
Kenichi Sugihara
Kenichi Sugihara Tokyo Medical and Dental University
Joseph R. Bertino
Joseph R. Bertino Rutgers, The State University of New Jersey

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