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Medicine

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Research.com Recognitions

  • 2026 - Research.com Medicine in Germany Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Best Scientists Award
  • 2023 - Research.com Medicine in Germany Leader Award
  • 2022 - Research.com Medicine in Germany Leader Award
  • 2019 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Neurosciences
  • 2015 - Royal Netherlands Academy of Arts and Sciences

Overview

Monique M.B. Breteler is affiliated with the German Center for Neurodegenerative Diseases in Germany. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a strong emphasis on neurodegenerative diseases and brain imaging techniques.

The scientist's work covers several key subfields, including radiology, nuclear medicine and imaging, molecular biology, cognitive neuroscience, genetics, and physiology. The primary topics researched include functional brain connectivity studies, advanced neuroimaging techniques and applications, epigenetics and DNA methylation, genetic associations and epidemiology, advanced MRI techniques and applications, diet and metabolism studies, as well as glaucoma and retinal disorders.

Frequent collaborators in their research projects include N. Ahmad Aziz, Martin Reuter, Santiago Estrada, Valerie Lohner, and Valentina Talevi. These collaborations have often resulted in multidisciplinary studies that intersect clinical and molecular approaches.

Monique M.B. Breteler has published extensively across renowned scientific journals and venues. The most common publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer's & Dementia
  • Nature Communications
  • Neurology
  • Aging Cell

Significant recent papers authored or co-authored by Monique M.B. Breteler include:

  • Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients, 2021, Genome Medicine
  • Genome-wide association study identifies 48 common genetic variants associated with handedness, 2020, Nature Human Behaviour
  • Seroprevalence and correlates of SARS-CoV-2 neutralizing antibodies from a population-based study in Bonn, Germany, 2021, Nature Communications
  • Relation Between Sex, Menopause, and White Matter Hyperintensities, 2022, Neurology
  • Physical activity is associated with slower epigenetic ageing-Findings from the Rhineland study, 2023, Aging Cell

Their publication record extends to over 150 contributions in medicine and 60 in biochemistry, genetics, and molecular biology, demonstrating a broad interdisciplinary approach.

Monique M.B. Breteler has been recognized by multiple scientific organizations. Awards include membership in the German National Academy of Sciences Leopoldina in 2019 for contributions in neurosciences, and the Royal Netherlands Academy of Arts and Sciences in 2015.

Best Publications

  • Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

    Joanna M. Wardlaw;Eric E. Smith;Geert J Biessels;Charlotte Cordonnier

  • Epidemiology of Parkinson's disease

    Lonneke M L de Lau;Monique M B Breteler

  • A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease

    Frank Jessen;Frank Jessen;Rebecca E. Amariglio;Martin van Boxtel;Monique Breteler

  • Silent brain infarcts and the risk of dementia and cognitive decline

    Sarah E Vermeer;Niels D Prins;Tom den Heijer;Albert Hofman

  • Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis

    R. Clarke;R. Collins;S. Lewington;A. Donald

  • Diabetes mellitus and the risk of dementia The Rotterdam Study

    Alewijn Ott;R. P. Stolk;F. van Harskamp;H. A. P. Pols

  • Ankle brachial index combined with Framingham risk score to predict cardiovascular events and mortality: A meta-analysis

    F.G.R. Fowkes;G.D. Murray;I. Butcher;C.L. Heald

  • Arterial Stiffness and Risk of Coronary Heart Disease and Stroke: The Rotterdam Study

    Francesco U.S. Mattace-Raso;Tischa J.M. van der Cammen;Albert Hofman;Nicole M. van Popele

  • National Institute of Neurological Disorders and Stroke–Canadian Stroke Network Vascular Cognitive Impairment Harmonization Standards

    Vladimir Hachinski;Costantino Iadecola;Ron C. Petersen;Monique M. Breteler

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Cerebral microbleeds: a guide to detection and interpretation

    Steven M. Greenberg;Meike W. Vernooij;Charlotte Cordonnier;Anand Viswanathan

  • Prevalence of dementia and major subtypes in Europe : A collaborative study of population-based cohorts

    A. Lobo;L. J. Launer;L. Fratiglioni;K. Andersen

  • Incidental findings on brain MRI in the general population.

    Meike W Vernooij;M Arfan Ikram;Hervé L Tanghe;Arnaud J P E Vincent

  • Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study.

    Albert Hofman;Alewijn Ott;Monique M B Breteler;Michiel L Bots

  • Physical Activity, Including Walking, And Cognitive Function In Older Women

    J Weuve;J H Kang;J E Manson;M Breteler

  • Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study

    F-E de Leeuw;J C de Groot;E Achten;M Oudkerk

  • Genome-wide analysis of genetic loci associated with Alzheimer disease.

    Sudha Seshadri;Annette L. Fitzpatrick;M Arfan Ikram;Anita L. DeStefano

  • Dietary Intake of Antioxidants and Risk of Alzheimer Disease

    Marianne J. Engelhart;Mirjam I. Geerlings;Annemieke Ruitenberg;John C. van Swieten

  • The Rotterdam Study: Objectives and design update

    Albert Hofman;Guy G. O. Brusselle;Sarwa Darwish Murad;Cornelia M. van Duijn

  • Cerebral white matter lesions, vascular risk factors, and cognitive function in a population‐based study The Rotterdam Study

    M.M.B. Breteler;J. C. van Swieten;M. L. Bots;D. E. Grobbee

Frequent Co-Authors

Albert Hofman
Albert Hofman Harvard University
Peter J. Koudstaal
Peter J. Koudstaal Erasmus University Rotterdam
Jacqueline C.M. Witteman
Jacqueline C.M. Witteman Erasmus University Rotterdam
M. Arfan Ikram
M. Arfan Ikram Erasmus University Rotterdam
Wiro J. Niessen
Wiro J. Niessen Erasmus University Rotterdam
Meike W. Vernooij
Meike W. Vernooij Erasmus University Rotterdam
Aad van der Lugt
Aad van der Lugt Erasmus University Rotterdam
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Lenore J. Launer
Lenore J. Launer National Institutes of Health
Gabriel P. Krestin
Gabriel P. Krestin Erasmus University Rotterdam

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