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D-Index & Metrics

Molecular Biology

D-Index
87
Citations
30095
World Ranking
796
National Ranking
13

Overview

Nicola Normanno is affiliated with the Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" in Italy and has an extensive research portfolio primarily focused on medicine and biochemistry, genetics, and molecular biology. Their work covers key subfields such as oncology, pulmonary and respiratory medicine, cancer research, molecular biology, and pathology and forensic medicine.

Their research addresses several critical topics including cancer genomics and diagnostics, lung cancer treatments and mutations, colorectal cancer treatments and studies, genetic factors in colorectal cancer, cancer immunotherapy and biomarkers, radiomics and machine learning in medical imaging, and gastric cancer management and outcomes.

Nicola Normanno has published numerous papers in respected journals, including these recent notable works:

  • Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up (2022), Annals of Oncology
  • Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group (2020), Annals of Oncology
  • ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group (2022), Annals of Oncology
  • Delivering precision oncology to patients with cancer (2022), Nature Medicine
  • Recommendations for the use of next-generation sequencing (NGS) for patients with advanced cancer in 2024: a report from the ESMO Precision Medicine Working Group (2024), Annals of Oncology

The scholar has collaborated frequently with several co-authors, including Carmine Pinto, Evaristo Maiello, Alessandro Morabito, Antonio Avallone, and Riziero Esposito Abate, reflecting a network of researchers engaged in oncology and precision medicine.

Normanno's publications span multiple prestigious venues, with significant contributions to:

  • Annals of Oncology
  • Cancers
  • Journal of Clinical Oncology
  • ESMO Open
  • Zenodo (CERN European Organization for Nuclear Research)

The researcher's body of work includes 378 publications in medicine and 163 in biochemistry, genetics, and molecular biology, evidencing deep interdisciplinary engagement. Their oncology-related publications count 147, while contributions in pulmonary and respiratory medicine reach 102. Additional substantial work has been published in cancer research and molecular biology, with 90 and 52 publications respectively.

The focus on cancer genomics and diagnostics is reflected in 168 publications, with related significant areas including lung and colorectal cancer studies. Normanno's research covers emerging areas such as cancer immunotherapy and the application of radiomics and machine learning in medical imaging, indicating active involvement in precision oncology trends.

Best Publications

  • Epidermal growth factor-related peptides and their receptors in human malignancies

    David S. Salomon;Ralf Brandt;Fortunato Ciardiello;Nicola Normanno

  • Epidermal growth factor receptor (EGFR) signaling in cancer

    Nicola Normanno;Antonella De Luca;Caterina Bianco;Luigi Strizzi

  • Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group.

    F. Mosele;J. Remon;J. Mateo;C. B. Westphalen

  • The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches.

    Unknown

  • Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment.

    N Normanno;C Bianco;A De Luca;M R Maiello

  • The role of the EGFR signaling in tumor microenvironment

    Unknown

  • The ErbB receptors and their ligands in cancer: an overview.

    N. Normanno;C. Bianco;L. Strizzi;M. Mancino

  • Implementing TMB measurement in clinical practice: considerations on assay requirements

    Reinhard Büttner;John W Longshore;Fernando López-Ríos;Sabine Merkelbach-Bruse

  • The role of EGF-related peptides in tumor growth.

    Normanno N;Bianco C;De Luca A;Salomon Ds

  • Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis

    Luigi Strizzi;Caterina Bianco;Nicola Normanno;David Salomon

  • Guidance for laboratories performing molecular pathology for cancer patients.

    Ian A Cree;Ian A Cree;Zandra Deans;Marjolijn J L Ligtenberg;Nicola Normanno

  • Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo

    Heather B. Adkins;Caterina Bianco;Susan G. Schiffer;Paul Rayhorn

  • Epithelial to mesenchymal transition by TGFβ-1 induction increases stemness characteristics in primary non small cell lung cancer cell line.

    Giuseppe Pirozzi;Virginia Tirino;Rosa Camerlingo;Renato Franco

  • The MEK/MAPK pathway is involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib

    Nicola Normanno;Antonella De Luca;Monica R. Maiello;Manuela Campiglio

  • EGFR mutation testing practices within the Asia Pacific region: results of a multicenter diagnostic survey.

    Yasushi Yatabe;Keith M Kerr;Ahmad Rusdan Handoyo Utomo;Pathmanathan A Rajadurai

  • Differential immunohistochemical detection of amphiregulin and cripto in human normal colon and colorectal tumors.

    Toshiaki Saeki;Kurt Stromberg;Chen Feng Qi;William J. Gullick

  • Cripto-1 Activates Nodal- and ALK4-Dependent and -Independent Signaling Pathways in Mammary Epithelial Cells

    Caterina Bianco;Heather B. Adkins;Heather B. Adkins;Christian Wechselberger;Masaharu Seno

  • The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.

    D S Saloman;C Bianco;A D Ebert;N I Khan

  • Epithelial mesenchymal transition is a characteristic of hyperplasias and tumors in mammary gland from MMTV-Cripto-1 transgenic mice.

    Luigi Strizzi;Caterina Bianco;Nicola Normanno;Masaharu Seno

  • Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs): simple drugs with a complex mechanism of action?

    Unknown

Frequent Co-Authors

Fortunato Ciardiello
Fortunato Ciardiello University of Campania "Luigi Vanvitelli"
David S. Salomon
David S. Salomon National Institutes of Health
Gerardo Botti
Gerardo Botti Istituto Giannina Gaslini
Renato Franco
Renato Franco University of Campania "Luigi Vanvitelli"
Aldo Scarpa
Aldo Scarpa University of Verona
Antonio Russo
Antonio Russo University of Palermo
Giuseppe Tonini
Giuseppe Tonini Università Campus Bio-Medico
Martin Reck
Martin Reck LungenClinic Grosshansdorf
Michele Caraglia
Michele Caraglia University of Campania "Luigi Vanvitelli"
Stefano Pepe
Stefano Pepe University of Salerno

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