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Biology and Biochemistry

D-Index
57
Citations
8655
World Ranking
14096
National Ranking
419

Overview

Stefano Pepe is affiliated with the University of Salerno in Italy and has conducted extensive research primarily within the field of medicine. Their work spans multiple subfields, including oncology, pulmonary and respiratory medicine, immunology, molecular biology, and computer networks and communications.

The research topics covered by Stefano Pepe are diverse, with a particular emphasis on cancer immunotherapy and biomarkers. Key focus areas include CAR-T cell therapy research, lung cancer treatments and mutations, lung cancer research studies, immunotherapy and immune responses, brain metastases and treatment, and phagocytosis and immune regulation.

Stefano Pepe's recent publications demonstrate a focus on checkpoint-based immunotherapy and cancer treatment mechanisms. Notable recent papers include:

  • "Role of Human Leukocyte Antigen System as A Predictive Biomarker for Checkpoint-Based Immunotherapy in Cancer Patients" (2020), published in International Journal of Molecular Sciences
  • "Enhanced Expression of CD47 Is Associated With Off-Target Resistance to Tyrosine Kinase Inhibitor Gefitinib in NSCLC" (2020), published in Frontiers in Immunology
  • "Immune checkpoint inhibitors for the treatment of melanoma" (2022), published in Expert Opinion on Biological Therapy
  • "Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors" (2021), published in Journal of Medicinal Chemistry
  • "Impact of COVID-19 outbreak on cancer immunotherapy in Italy: a survey of young oncologists" (2020), published in Journal for ImmunoTherapy of Cancer

The frequent co-authors collaborating with Stefano Pepe include Francesco Sabbatino, Giovanna Polcaro, Luigi Liguori, Angelo Luciano, and Jessica Dal Col. The number of collaborations varies, with the highest count of joint publications being with Francesco Sabbatino.

Stefano Pepe's research has been published in several journals with multiple contributions to notable venues such as Frontiers in Immunology, Preprints.org, International Journal of Molecular Sciences, Expert Opinion on Biological Therapy, and Journal of Medicinal Chemistry.

Best Publications

  • Antitumor Activity of Sequential Treatment with Topotecan and Anti-Epidermal Growth Factor Receptor Monoclonal Antibody C225

    Fortunato Ciardiello;Roberto Bianco;Vincenzo Damiano;Sonya De Lorenzo

  • The Multiple Sulfatase Deficiency Gene Encodes an Essential and Limiting Factor for the Activity of Sulfatases

    Maria Pia Cosma;Stefano Pepe;Ida Annunziata;Robert F Newbold

  • A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients

    F De Vita;M Orditura;E Matano;R Bianco

  • Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa)

    Cataldo Bianco;Giampaolo Tortora;Roberto Bianco;Roberta Caputo

  • BRAF is a therapeutic target in aggressive thyroid carcinoma.

    Giuliana Salvatore;Valentina De Falco;Paolo Salerno;Tito Claudio Nappi

  • p53 Alterations in Non-Small Cell Lung Cancers Correlate with Metastatic Involvement of Hilar and Mediastinal Lymph Nodes

    Marchetti A;Buttitta F;Merlo G;Diella F

  • cAMP-dependent protein kinase: role in normal and malignant growth

    Yoon S. Cho-Chung;Stefano Pepe;Timothy Clair;AlfreD.O. Budillon

  • A Specific miRNA Signature Correlates With Complete Pathological Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

    Giuseppina Della Vittoria Scarpati;Francesca Falcetta;Chiara Carlomagno;Paolo Ubezio

  • Twenty-year results of the Naples GUN randomized trial: predictive factors of adjuvant tamoxifen efficacy in early breast cancer.

    Sabino De Placido;Michelino De Laurentiis;Chiara Carlomagno;Ciro Gallo

  • Periodic activation of Wnt/beta-catenin signaling enhances somatic cell reprogramming mediated by cell fusion.

    Frederic Lluis;Elisa Pedone;Stefano Pepe;Maria Pia Cosma

  • Epidermal Growth Factor Receptor (EGFr) Expression in Non-small Cell Lung Carcinomas Correlates with Metastatic Involvement of Hilar and Mediastinal Lymph Nodes in the Squamous Subtype

    G. Fontanini;S. Vignati;D. Bigini;A. Mussi

  • Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells

    Elena Di Gennaro;Marcella Barbarino;Francesca Bruzzese;Sonya De Lorenzo

  • Sequence-dependent antiproliferative effects of cytotoxic drugs and epidermal growth factor receptor inhibitors

    M. P. Morelli;T. Cascone;T. Troiani;T. Troiani;F. De Vita

  • Desferioxamine increases iron depletion and apoptosis induced by ara-C of human myeloid leukaemic cells.

    A. Leardi;M. Caraglia;Carmine Selleri;Stefano Pepe

  • Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications

    Francesco Perri;Roberto Pacelli;Giuseppina Della Vittoria Scarpati;Laura Cella

  • Differentiation of HL-60 leukemia by type I regulatory subunit antisense oligodeoxynucleotide of cAMP-dependent protein kinase.

    Giampaolo Tortora;Hiroshi Yokozaki;Stefano Pepe;Timothy Clair

  • Correction of Hunter syndrome in the MPSII mouse model by AAV2/8-mediated gene delivery

    Monica Cardone;Vinicia Assunta Polito;Stefano Pepe;Linda Mann

  • The expression of proliferating cell nuclear antigen in paraffin sections of peripheral, node-negative non-small cell lung cancer.

    Gabriella Fontanini;Paolo Macchiarini;Stefano Pepe;Angela Ruggievo

  • Cooperative Inhibition of Renal Cancer Growth by Anti-Epidermal Growth Factor Receptor Antibody and Protein Kinase A Antisense Oligonucleotide

    Fortunato Ciardiello;Rosa Caputo;Roberto Bianco;Vincenzo Damiano

  • Ipilimumab in the treatment of metastatic melanoma: management of adverse events

    Giuseppina Della Vittoria Scarpati;Celeste Fusciello;Francesco Perri;Francesco Sabbatino

Frequent Co-Authors

Fortunato Ciardiello
Fortunato Ciardiello University of Campania "Luigi Vanvitelli"
Giampaolo Tortora
Giampaolo Tortora University of Verona
Michele Caraglia
Michele Caraglia University of Campania "Luigi Vanvitelli"
Sabino De Placido
Sabino De Placido University of Naples Federico II
Alfredo Budillon
Alfredo Budillon Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
Yoon S. Cho-Chung
Yoon S. Cho-Chung National Institutes of Health
Soldano Ferrone
Soldano Ferrone Harvard University
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Nicola Normanno
Nicola Normanno Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
Alberto Abbruzzese
Alberto Abbruzzese University of Campania "Luigi Vanvitelli"

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