World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
30880
World Ranking
2932
National Ranking
1502

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Joseph R. Bertino was affiliated with Rutgers, The State University of New Jersey in the United States. Their research contributions spanned multiple domains including pharmacology, oncology, and pediatrics, with a focus on pharmacogenetics, drug metabolism, and cancer therapy.

The scientist's recent publications included:

  • Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis, 2021, Nature Cancer
  • S-warfarin limited sampling strategy with a population pharmacokinetic approach to estimate exposure and cytochrome P450 (CYP) 2C9 activity in healthy adults, 2021, European Journal of Clinical Pharmacology
  • Issue Information, 2023, The Journal of Clinical Pharmacology
  • The Journal of Clinical Pharmacology Adds 2 Associate Editors, 2021, The Journal of Clinical Pharmacology
  • Issue Information, 2021, The Journal of Clinical Pharmacology

Their frequent co-authors were:

  • Elizabeth Marshall
  • Donald Adler
  • Mckeen Cattell
  • Deborah Keefe
  • Guohua An

Joseph R. Bertino published extensively in the following venues:

  • The Journal of Clinical Pharmacology
  • Nature Cancer
  • European Journal of Clinical Pharmacology
  • UNC Libraries

The subfields in which they conducted research included:

  • Pharmacology
  • Oncology
  • Pediatrics, Perinatology and Child Health
  • Pathology and Forensic Medicine
  • Molecular Biology

Main topics of their work were focused on:

  • Pharmacogenetics and Drug Metabolism
  • Pharmaceutical studies and practices
  • Cancer Mechanisms and Therapy
  • Peptidase Inhibition and Analysis
  • Signaling Pathways in Disease
  • Biosimilars and Bioanalytical Methods
  • Statistical Methods in Clinical Trials

Joseph R. Bertino was recognized as a member of the Association of American Physicians. Their career reflected an extensive commitment to clinical pharmacology and related biomedical research fields.

Best Publications

  • Prognostic effect of weight loss prior tochemotherapy in cancer patients

    William D. Dewys;Colin Begg;Philip T. Lavin;Pierre R. Band

  • Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

    Carlos Cordon-Cardo;James P. O'Brien;Dolors Casals;Lana Rittman-Grauer

  • Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

    C Cordon-Cardo;J P O'Brien;J Boccia;D Casals

  • Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

    F W Alt;R E Kellems;J R Bertino;R T Schimke

  • A 2-step comprehensive high-dose chemoradiotherapy second-line program for relapsed and refractory Hodgkin disease: analysis by intent to treat and development of a prognostic model

    Craig H. Moskowitz;Stephen D. Nimer;Andrew D. Zelenetz;Tania Trippett

  • Fluorouracil in colorectal cancer--a tale of two drugs: implications for biochemical modulation.

    Alberto F. Sobrero;Carlo Aschele;Joseph R. Bertino

  • Ifosfamide, Carboplatin, and Etoposide: A Highly Effective Cytoreduction and Peripheral-Blood Progenitor-Cell Mobilization Regimen for Transplant-Eligible Patients With Non-Hodgkin's Lymphoma

    Craig H. Moskowitz;Joseph R. Bertino;Jill R. Glassman;Eric E. Hedrick

  • Karnofsky memorial lecture. Ode to methotrexate.

    Joseph R. Bertino

  • Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis

    Alexandru Almasan;Yuxin Yin;Yuxin Yin;Ruth E. Kelly;Eva Y. H. P. Lee

  • Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.

    Debabrata Banerjee;Philipp Mayer-Kuckuk;Gina Capiaux;Gina Capiaux;Tulin Budak-Alpdogan

  • Intrinsic and Acquired Resistance to Methotrexate in Acute Leukemia

    Richard Gorlick;Erdem Goker;Tanya Trippett;Mark Waltham

  • Acute nonlymphocytic leukemia: a delayed complication of Hodgkin's disease therapy: analysis of 109 cases.

    E. C. Cadman;R. L. Capizzi;J. R. Bertino

  • Enzymatic synthesis and function of folylpolyglutamates.

    John J. McGuire;Joseph R. Bertino

  • Potential Regional Differences for the Tolerability Profiles of Fluoropyrimidines

    Daniel G. Haller;Jim Cassidy;Stephen J. Clarke;David Cunningham

  • Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression

    Richard Gorlick;Erdem Goker;Erdem Goker;Tanya Trippett;Tanya Trippett;Peter Steinherz;Peter Steinherz

  • Phase I Study of Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic Irinotecan for Unresectable Hepatic Metastases From Colorectal Cancer

    Nancy E. Kemeny;M. Gonen;D. Sullivan;L. Schwartz

  • Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.

    Ting-Chao Chou;Xiu-Guo Zhang;Christina R. Harris;Scott D. Kuduk

  • STUDIES ON THE INHIBITION OF DIHYDROFOLATE REDUCTASE BY THE FOLATE ANTAGONISTS.

    Joseph R. Bertino;Barbara A. Booth;Allan L. Bieber;Arlene Cashmore

  • Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207)

    David A. Kooby;John F. Carew;Marc W. Halterman;Jonathan E. Mack

  • Purification and properties of carboxypeptidase G 1 .

    J. L. McCullough;B. A. Chabner;Joseph Bertino

Frequent Co-Authors

Richard Gorlick
Richard Gorlick The University of Texas MD Anderson Cancer Center
Nancy E. Kemeny
Nancy E. Kemeny Memorial Sloan Kettering Cancer Center
Peter V. Danenberg
Peter V. Danenberg University of Southern California
Carlos Cordon-Cardo
Carlos Cordon-Cardo Icahn School of Medicine at Mount Sinai
Kathleen D. Danenberg
Kathleen D. Danenberg University of Southern California
Andrew D. Zelenetz
Andrew D. Zelenetz Memorial Sloan Kettering Cancer Center
Yuman Fong
Yuman Fong City Of Hope National Medical Center
Suresh C. Jhanwar
Suresh C. Jhanwar Memorial Sloan Kettering Cancer Center
David J. Straus
David J. Straus Memorial Sloan Kettering Cancer Center
Leonard Saltz
Leonard Saltz Memorial Sloan Kettering Cancer Center

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