What is he best known for?
The fields of study he is best known for:
Molecular biology, Endocrinology, Internal medicine, Protein kinase C and Cell culture are his primary areas of study.
His studies in Molecular biology integrate themes in fields like Complementary DNA, Gene, Transforming growth factor, Transforming growth factor, beta 3 and TGF beta 1.
His Internal medicine study integrates concerns from other disciplines, such as Rottlerin and Microgram.
His research in Protein kinase C focuses on subjects like Activator, which are connected to In vitro.
His work carried out in the field of Cell culture brings together such families of science as Tumor suppressor gene, Receptor, Cancer research and Extracellular.
His Receptor research incorporates themes from Calcitriol, Cell and Pathology.
His most cited work include:
- Production of hydrogen peroxide by transforming growth factor-beta 1 and its involvement in induction of egr-1 in mouse osteoblastic cells. (446 citations)
- Regulation of Terminal Differentiation of Cultured Mouse Epidermal Cells by lα,25-Dihydroxyvitamin D3 (427 citations)
- Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis (352 citations)
What are the main themes of his work throughout his whole career to date?
Toshio Kuroki mostly deals with Molecular biology, Protein kinase C, Biochemistry, Cell culture and Internal medicine.
The Molecular biology study combines topics in areas such as Carcinogenesis, Gene expression, Gene, Phosphorylation and Epidermis.
His study in Carcinogenesis is interdisciplinary in nature, drawing from both Cellular aspects and Pathology.
The concepts of his Protein kinase C study are interwoven with issues in Protein kinase A and Gene isoform.
He interconnects Cell and Receptor in the investigation of issues within Cell culture.
His studies link Endocrinology with Internal medicine.
He most often published in these fields:
- Molecular biology (42.93%)
- Protein kinase C (23.56%)
- Biochemistry (23.04%)
What were the highlights of his more recent work (between 1998-2019)?
- Protein kinase C (23.56%)
- Cell biology (15.71%)
- Cancer research (10.99%)
In recent papers he was focusing on the following fields of study:
Toshio Kuroki mainly focuses on Protein kinase C, Cell biology, Cancer research, Internal medicine and Molecular biology.
The study incorporates disciplines such as Apoptosis and Protein kinase A in addition to Protein kinase C.
In his research on the topic of Cell biology, Actin, GRB2, Microinjection, Cytoplasm and Keratinocyte is strongly related with Cell growth.
His Cancer research research includes themes of Colorectal cancer, DNA mismatch repair, Gene, Tetradecanoylphorbol Acetate and Gefitinib.
The Internal medicine study which covers Endocrinology that intersects with PI3K/AKT/mTOR pathway.
His Molecular biology research also works with subjects such as
- Wild type most often made with reference to Cell culture,
- Mutant which is related to area like Chinese hamster ovary cell.
Between 1998 and 2019, his most popular works were:
- Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis (352 citations)
- Frequent Mutation of β-Catenin and APC Genes in Primary Colorectal Tumors from Patients with Hereditary Nonpolyposis Colorectal Cancer (191 citations)
- Involvement of Protein Kinase C δ (PKCδ) in Phorbol Ester-induced Apoptosis in LNCaP Prostate Cancer Cells LACK OF PROTEOLYTIC CLEAVAGE OF PKCδ (184 citations)
In his most recent research, the most cited papers focused on:
Protein kinase C, Internal medicine, Endocrinology, Cancer research and Insulin are his primary areas of study.
His Protein kinase C research is classified as research in Cell biology.
His Pancreatic hormone, NADPH oxidase and Oxidative stress study in the realm of Endocrinology connects with subjects such as Adipocyte.
His Cancer research research includes elements of Distant metastasis, Colorectal cancer, Tetradecanoylphorbol Acetate and Pathology.
Insulin receptor substrate and Insulin receptor is closely connected to Phosphorylation in his research, which is encompassed under the umbrella topic of Insulin.
His Protein kinase A research incorporates elements of Gene expression, Transcription factor, Molecular biology, Ccaat-enhancer-binding proteins and MAPK/ERK pathway.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
