World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
8909
World Ranking
12222
National Ranking
5220

Overview

Jack Henkin is affiliated with Northwestern University in the United States. Their research primarily spans the field of Medicine, with a focus on Infectious Diseases, Neurology, Genetics, Ophthalmology, and Physiology as subfields.

The main topics of their work include SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Long-Term Effects of COVID-19, Alzheimer's disease research and treatments, Retinopathy of Prematurity Studies, Neonatal Health and Biochemistry, and Neonatal Respiratory Health Research.

Jack Henkin has coauthored multiple papers with collaborators such as Luise Hassler, Jan Wysocki, Haley Gula, Glenn Randall, and Daniel Batlle.

Recent publications include:

  • A Novel Soluble ACE2 Protein Provides Lung and Kidney Protection in Mice Susceptible to Lethal SARS-CoV-2 Infection, 2022, Journal of the American Society of Nephrology
  • A novel soluble ACE2 protein totally protects from lethal disease caused by SARS-CoV-2 infection, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • Inhibition of retinal neovascularization by a PEDF-derived nonapeptide in newborn mice subjected to oxygen-induced ischemic retinopathy, 2020, Experimental Eye Research
  • Pigment epithelium-derived factor attenuates angiogenesis and collagen deposition in hypertrophic scars, 2020, Wound Repair and Regeneration
  • Intranasal soluble ACE2 improves survival and prevents brain SARS-CoV-2 infection, 2023, Life Science Alliance

Henkin frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Experimental Eye Research, Journal of the American Society of Nephrology, Life Science Alliance, and Cells.

Best Publications

  • Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis: Implications for cellular surrogate marker analysis of antiangiogenesis

    Yuval Shaked;Francesco Bertolini;Shan Man;Michael S. Rogers

  • Paclitaxel at ultra low concentrations inhibits angiogenesis without affecting cellular microtubule assembly.

    Jieyi Wang;Pingping Lou;Rick Lesniewski;Jack Henkin

  • Structural requirements for the growth factor activity of the amino-terminal domain of urokinase.

    Shafaat A. Rabbani;Andrew P. Mazar;Suzanne M. Bernier;Mahmudul Haq

  • Kringle 5 of Human Plasminogen Induces Apoptosis of Endothelial and Tumor Cells through Surface-Expressed Glucose-Regulated Protein 78

    Don J. Davidson;Catherine Haskell;Sandy Majest;Abdullah Kherzai

  • Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

    Michael P. Plebanek;Nicholas L. Angeloni;Elena Vinokour;Jia Li

  • Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates cellular uptake of pro-urokinase.

    M Z Kounnas;J Henkin;W S Argraves;D K Strickland

  • The urokinase plasminogen activator system in cancer: implications for tumor angiogenesis and metastasis.

    Andrew P. Mazar;Jack Henkin;Ronald H. Goldfarb

  • AN AMINO-TERMINAL FRAGMENT OF UROKINASE ISOLATED FROM A PROSTATE CANCER CELL LINE (PC-3) IS MITOGENIC FOR OSTEOBLAST-LIKE CELLS

    Shafast A. Rabbani;Johanne Desjardins;Alexander W. Bell;Denis Banville

  • Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: design, synthesis, and optimization of pharmacokinetics and biological activities.

    Fortuna Haviv;Michael F. Bradley;Douglas M. Kalvin;Andrew J. Schneider

  • Three Distinct d-Amino Acid Substitutions Confer Potent Antiangiogenic Activity on an Inactive Peptide Derived from a Thrombospondin-1 Type 1 Repeat

    D. W. Dawson;O. V. Volpert;S. F. A. Pearce;A. J. Schneider

  • Involvement of urokinase and its receptor in the invasiveness of human prostatic carcinoma cell lines.

    Naseema M. Hoosein;Douglas D. Boyd;William J. Hollas;Andrew Mazar

  • Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics

    Frank K. Reiher;Olga V. Volpert;Benilde Jimenez;Benilde Jimenez;Susan E. Crawford

  • Prevention of prostate-cancer metastasis in vivo by a novel synthetic inhibitor of urokinase-type plasminogen activator (uPA)

    Shafaat Rabbani;Penelope Harakidas;Donald J. Davidson;Jack Henkin

  • Physiologically relevant metal cofactor for methionine aminopeptidase-2 is manganese.

    Jieyi Wang;George S. Sheppard;Pingping Lou;Megumi Kawai

  • Enhancement of the Enzymatic Activity of Single-chain Urokinase Plasminogen Activator by Soluble Urokinase Receptor

    Abd Al-Roof Higazi;Robert L. Cohen;Jack Henkin;Douglas Kniss

  • Interaction of single-chain urokinase-type plasminogen activator with human endothelial cells.

    E S Barnathan;A Kuo;L Rosenfeld;K Karikó

  • Embryonic Fibroblasts That Are Genetically Deficient in Low Density Lipoprotein Receptor-related Protein Demonstrate Increased Activity of the Urokinase Receptor System and Accelerated Migration on Vitronectin

    Alissa M. Weaver;Isa M. Hussaini;Andrew Mazar;Jack Henkin

  • Prevention of breast cancer growth, invasion, and metastasis by antiestrogen tamoxifen alone or in combination with urokinase inhibitor B-428.

    Rosie Hongmei Xing;Andrew Mazar;Jack Henkin;Shafaat Ahmed Rabbani

  • Selective inhibition of endothelial cell proliferation by fumagillin is not due to differential expression of methionine aminopeptidases.

    Jieyi Wang;Pingping Lou;Jack Henkin

  • Tumor suppression by a rationally designed reversible inhibitor of methionine aminopeptidase-2.

    Jieyi Wang;George S. Sheppard;Pingping Lou;Megumi Kawai

Frequent Co-Authors

Andrew P. Mazar
Andrew P. Mazar Northwestern University
Douglas B. Cines
Douglas B. Cines University of Pennsylvania
Stephen F. Badylak
Stephen F. Badylak University of Pittsburgh
Noel P. Bouck
Noel P. Bouck Northwestern University
Christine M. Sorenson
Christine M. Sorenson University of Wisconsin–Madison
Nader Sheibani
Nader Sheibani University of Wisconsin–Madison
Douglas D. Boyd
Douglas D. Boyd The University of Texas MD Anderson Cancer Center
Katalin Karikó
Katalin Karikó University of Pennsylvania
Marcelo Calderón
Marcelo Calderón University of the Basque Country
Rainer Haag
Rainer Haag Freie Universität Berlin

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