Katalin Karikó

Research.com Recognitions

• 2022 - Japan Prize for pioneering research contributing to the development of mRNA vaccines.
• 2022 - Paul Ehrlich and Ludwig Darmstaedter Prize
• 2022 - Breakthrough Prize in Life Sciences for engineering modified RNA technology which enabled rapid development of effective COVID-19 vaccines.
• 2021 - Louisa Gross Horwitz Prize, Columbia University
• 2021 - Albany Medical Center Prize in Medicine and Biomedical Research
• 2020 - Member of Academia Europaea

Overview

Best Publications

• Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA

  Katalin Karikó;Michael Buckstein;Houping Ni;Drew Weissman

  2770
  Citations

• mRNA-based therapeutics — developing a new class of drugs

  Ugur Sahin;Katalin Karikó;Özlem Türeci

  2478
  Citations

• COVID-19 vaccine BNT162b1 elicits human antibody and T H 1 T cell responses.

  Ugur Sahin;Alexander Muik;Evelyna Derhovanessian;Isabel Vogler

  2204
  Citations

• Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.

  Katalin Karikó;Hiromi Muramatsu;Frank A Welsh;János Ludwig

  2018
  Citations

• mRNA Is an Endogenous Ligand for Toll-like Receptor 3

  Katalin Karikó;Houping Ni;John Capodici;Marc Lamphier

  1388
  Citations

• Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

  Mark E. Kleinman;Kiyoshi Yamada;Atsunobu Takeda;Vasu Chandrasekaran

  1092
  Citations

• Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes.

  Norbert Pardi;Steven Tuyishime;Hiromi Muramatsu;Katalin Kariko

  1001
  Citations

• Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA

  Katalin Karikó;Hiromi Muramatsu;János Ludwig;Drew Weissman

  987
  Citations

• Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

  Norbert Pardi;Michael J. Hogan;Rebecca S. Pelc;Hiromi Muramatsu

  898
  Citations

• Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

  Bart R. Anderson;Hiromi Muramatsu;Subba R. Nallagatla;Philip C. Bevilacqua

  760
  Citations

• BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans.

  Ugur Sahin;Alexander Muik;Isabel Vogler;Evelyna Derhovanessian

  760
  Citations

• DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

  Hiroki Kaneko;Sami Dridi;Valeria Tarallo;Bradley D. Gelfand

  708
  Citations

• Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses

  Mohamad-Gabriel Alameh;István Tombácz;Emily Bettini;Katlyn Lederer

  666
  Citations

• Small Interfering RNAs Mediate Sequence-Independent Gene Suppression and Induce Immune Activation by Signaling through Toll-Like Receptor 3

  Katalin Karikó;Prakash Bhuyan;John Capodici;Drew Weissman

  567
  Citations

• Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

  Norbert Pardi;Michael J. Hogan;Martin S. Naradikian;Kaela Parkhouse

  485
  Citations

• Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference.

  John Capodici;Katalin Karikó;Drew Weissman

  446
  Citations

• Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L

  Bart R. Anderson;Hiromi Muramatsu;Babal K. Jha;Robert H. Silverman

  398
  Citations

• Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin

  Katalin Karikó;Hiromi Muramatsu;Jason M Keller;Drew Weissman

  375
  Citations

• A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA

  Markus Baiersdörfer;Gábor Boros;Hiromi Muramatsu;Azita Mahiny

  364
  Citations

• Inhibition of Toll-like receptor and cytokine signaling: A unifying theme in ischemic tolerance

  Katalin Karikó;Drew Weissman;Frank A Welsh

  338
  Citations