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Biology and Biochemistry

D-Index
83
Citations
22989
World Ranking
3533
National Ranking
1771

Overview

Peter J. Newman is affiliated with the Medical College of Wisconsin in the United States. Their research primarily focuses on the field of Medicine, with a significant emphasis on Hematology. Subfields of their work include Immunology and Allergy, Immunology, Genetics, and Molecular Biology.

Their main research topics cover areas such as Platelet Disorders and Treatments, Blood groups and transfusion, Cell Adhesion Molecules Research, Blood disorders and treatments, Monoclonal and Polyclonal Antibodies Research, Heparin-Induced Thrombocytopenia and Thrombosis, and Glycosylation and Glycoproteins Research.

Peter J. Newman has contributed to numerous publications, frequently appearing in the following venues:

  • Blood
  • Blood Advances
  • Journal of Thrombosis and Haemostasis
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Journal of Cellular and Molecular Medicine

Selected recent papers include:

  • Overlapping and unique substrate specificities of ST3GAL1 and 2 during hematopoietic and megakaryocytic differentiation, 2022, Blood Advances
  • Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function, 2021, Arteriosclerosis Thrombosis and Vascular Biology
  • Prophylactic administration of HPA-1a-specific antibodies prevents fetal/neonatal alloimmune thrombocytopenia in mice, 2022, Blood
  • Generation of 'designer erythroblasts' lacking one or more blood group systems from CRISPR/Cas9 gene-edited human-induced pluripotent stem cells, 2021, Journal of Cellular and Molecular Medicine
  • Preclinical evaluation of immunotherapeutic regimens for fetal/neonatal alloimmune thrombocytopenia, 2021, Blood Advances

Frequent collaborators in Peter J. Newman's work include Huiying Zhi, Debra K. Newman, Nanyan Zhang, Alyssa J. Moroi, and Brian R. Curtis.

Best Publications

  • PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily

    Peter J. Newman;Michael C. Berndt;Jack Gorski;Gilbert C. White

  • Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule.

    Steven M. Albelda;William A. Muller;Clayton A. Buck;Peter J. Newman

  • The biology of PECAM-1.

    P J Newman

  • The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing.

    P J Newman;R S Derbes;R H Aster

  • Integrins: dynamic scaffolds for adhesion and signaling in platelets.

    Sanford J. Shattil;Peter J. Newman

  • Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery.

    J N George;E B Pickett;S Saucerman;R P McEver

  • Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31)

    Panida Lertkiatmongkol;Danying Liao;Heng Mei;Yu Hu

  • Signal Transduction Pathways Mediated by PECAM-1: New Roles for an Old Molecule in Platelet and Vascular Cell Biology

    Peter J. Newman;Debra K. Newman

  • Molecular and functional aspects of PECAM-1/CD31.

    Horace M. DeLisser;Peter J. Newman;Peter J. Newman;Steven M. Albelda

  • CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion.

    Y Tanaka;S M Albelda;K J Horgan;G A van Seventer

  • Nomenclature of human platelet antigens.

    P. Metcalfe;N. A. Watkins;W. H. Ouwehand;W. H. Ouwehand;C. Kaplan

  • Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development

    H.S. Baldwin;H.M. Shen;H.C. Yan;H.M. DeLisser

  • PECAM-1: regulator of endothelial junctional integrity

    Jamie R. Privratsky;Peter J. Newman

  • Switched at birth: a new family for PECAM-1

    Peter J. Newman

  • The Protein-tyrosine Phosphatase SHP-2 Binds Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Forms a Distinct Signaling Complex during Platelet Aggregation EVIDENCE FOR A MECHANISTIC LINK BETWEEN PECAM-1- AND INTEGRIN-MEDIATED CELLULAR SIGNALING

    Denise E. Jackson;Christopher M. Ward;Ronggang Wang;Peter J. Newman;Peter J. Newman

  • Structure of the human gene encoding granule membrane protein-140, a member of the selectin family of adhesion receptors for leukocytes.

    G I Johnston;G A Bliss;P J Newman;R P McEver

  • The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31).

    Ulrich J.H. Sachs;Cornelia L. Andrei-Selmer;Amudhan Maniar;Timo Weiss

  • Individually Distinct Ig Homology Domains in PECAM-1 Regulate Homophilic Binding and Modulate Receptor Affinity

    Qi-Hong Sun;Horace M. DeLisser;Mark M. Zukowski;Cathy Paddock

  • The molecular immunology of human platelet proteins.

    TJ Kunicki;PJ Newman

  • Enzymatic amplification of platelet-specific messenger RNA using the polymerase chain reaction.

    P J Newman;J Gorski;G C White nd;S Gidwitz

Frequent Co-Authors

Debra K. Newman
Debra K. Newman Medical College of Wisconsin
Richard H. Aster
Richard H. Aster Medical College of Wisconsin
Sentot Santoso
Sentot Santoso University of Giessen
Steven M. Albelda
Steven M. Albelda University of Pennsylvania
Robert R. Montgomery
Robert R. Montgomery Medical College of Wisconsin
Mortimer Poncz
Mortimer Poncz Children's Hospital of Philadelphia
Brian R. Curtis
Brian R. Curtis University of Wisconsin–Milwaukee
William A. Muller
William A. Muller Northwestern University
Demin Wang
Demin Wang Medical College of Wisconsin

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