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Molecular Biology

D-Index
43
Citations
10655
World Ranking
2955
National Ranking
41

Overview

Rolf Wibom is affiliated with the Karolinska Institute in Sweden and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology. Their research spans various subfields including Clinical Biochemistry, Renewable Energy, Sustainability and the Environment, Cancer Research, and Physiology.

The scientist's research topics prominently include:

  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Metabolism and Genetic Disorders
  • Metalloenzymes and iron-sulfur proteins
  • RNA and protein synthesis mechanisms
  • Cancer, Hypoxia, and Metabolism
  • Adipose Tissue and Metabolism

Rolf Wibom has published in several scientific venues, with a frequency in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Human Mutation
  • Neurology Genetics
  • Science Advances

Their recent papers include:

  • "The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters" (2021, Science Advances)
  • "Human mitochondria require mtRF1 for translation termination at non-canonical stop codons" (2023, Nature Communications)
  • "ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing" (2022, Nature Communications)
  • "Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity" (2024, Nature Metabolism)
  • "Severe congenital lactic acidosis and hypertrophic cardiomyopathy caused by an intronic variant in NDUFB7" (2021, Human Mutation)

Frequent co-authors include:

  • Anna Wredenberg
  • Roberta Filograna
  • Christoph Freyer
  • Anna Wedell
  • Nils-Göran Larsson

Best Publications

  • Premature ageing in mice expressing defective mitochondrial DNA polymerase

    Aleksandra Trifunovic;Anna Wredenberg;Maria Falkenberg;Johannes N. Spelbrink

  • Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

    Aleksandra Trifunovic;Anna Hansson;Anna Wredenberg;Anja T. Rovio

  • Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo

    Fredrik H. Sterky;Seungmin Lee;Rolf Wibom;Lars Olson

  • LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

    Benedetta Ruzzenente;Benedetta Ruzzenente;Metodi D Metodiev;Anna Wredenberg;Ana Bratic;Ana Bratic

  • Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome.

    Metodi D. Metodiev;Nicole Lesko;Chan Bae Park;Yolanda Cámara

  • Increased mitochondrial mass in mitochondrial myopathy mice.

    Anna Wredenberg;Rolf Wibom;Hans Wilhelmsson;Caroline Graff

  • MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome

    Yolanda Camara;Jorge Asin-Cayuela;Chan Bae Park;Metodi D. Metodiev

  • MTERF3 Is a Negative Regulator of Mammalian mtDNA Transcription

    Chan Bae Park;Jorge Asin-Cayuela;Yolanda Cámara;Yonghong Shi

  • Adaptation of mitochondrial ATP-production in human skeletal muscle to endurance training and detraining

    Rolf Wibom;Erik Hultman;Mats Johansson;Kaj Matherei

  • Alterations of mitochondrial function and correlations with personality traits in selected major depressive disorder patients

    Ann Gardner;Anna Johansson;Rolf Wibom;Inger Nennesmo

  • Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart.

    Sukru Anil Dogan;Claire Pujol;Priyanka Maiti;Alexandra Kukat

  • A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts.

    Anna Hansson;Nicole Hance;Eric Dufour;Anja Rantanen

  • Measurement of ATP production and respiratory chain enzyme activities in mitochondria isolated from small muscle biopsy samples.

    Rolf Wibom;Lars Hagenfeldt;Ulrika von Döbeln

  • AGC1 deficiency associated with global cerebral hypomyelination.

    Rolf Wibom;Francesco M. Lasorsa;Virpi Töhönen;Michela Barbaro

  • Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance.

    Anna Wredenberg;Christoph Freyer;Marie E. Sandström;Abram Katz

  • MTERF1 Binds mtDNA to Prevent Transcriptional Interference at the Light-Strand Promoter but Is Dispensable for rRNA Gene Transcription Regulation

    Mügen Terzioglu;Benedetta Ruzzenente;Julia Harmel;Arnaud Mourier

  • CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels.

    Karolina Szczepanowska;Priyanka Maiti;Alexandra Kukat;Eduard Hofsetz

  • Effects of Palmitate on Ca2+ Handling in Adult Control and ob/ob Cardiomyocytes : Impact of Mitochondrial Reactive Oxygen Species

    Jérémy Fauconnier;Daniel C. Andersson;Shi-Jin Zhang;Johanna T. Lanner

  • Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes.

    Ramin Tehranchi;Rosangela Invernizzi;Alf Grandien;Boris Zhivotovsky

  • Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion.

    Siri Malmgren;David G. Nicholls;Jalal Taneera;Karl Bacos

Frequent Co-Authors

Nils-Göran Larsson
Nils-Göran Larsson Karolinska Institute
Anna Wedell
Anna Wedell Karolinska University Hospital
Kjell Hultenby
Kjell Hultenby Karolinska Institute
Claes M. Gustafsson
Claes M. Gustafsson University of Gothenburg
Maria Falkenberg
Maria Falkenberg University of Gothenburg
Bianca Habermann
Bianca Habermann Aix-Marseille University
Håkan Westerblad
Håkan Westerblad Karolinska Institute
Emma L. Blakely
Emma L. Blakely Newcastle University
Hediye Erdjument-Bromage
Hediye Erdjument-Bromage New York University
Paul Tempst
Paul Tempst Memorial Sloan Kettering Cancer Center

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