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Biology and Biochemistry

D-Index
54
Citations
10745
World Ranking
15623
National Ranking
429

Overview

Aleksandra Filipovska is affiliated with the University of Western Australia in Australia and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology. Their body of work includes research in subfields such as Clinical Biochemistry, Physiology, Cancer Research, and Cell Biology.

The scientist's research topics prominently cover Mitochondrial Function and Pathology, RNA modifications and cancer, RNA and protein synthesis mechanisms, ATP Synthase and ATPases Research, Metabolism and Genetic Disorders, RNA Research and Splicing, and Adipose Tissue and Metabolism.

Recent papers by Aleksandra Filipovska include:

  • Organization and expression of the mammalian mitochondrial genome (2022, Nature Reviews Genetics)
  • The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication (2021, Science Advances)
  • Stepwise maturation of the peptidyl transferase region of human mitoribosomes (2021, Nature Communications)
  • The FASTK family proteins fine-tune mitochondrial RNA processing (2021, PLoS Genetics)
  • Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis (2020, Journal of Cell Science)

Frequent co-authors in their publications are:

  • Oliver Rackham
  • Stefan J. Siira
  • Danielle L. Rudler
  • Maike Stentenbach
  • Judith A. Ermer

Filipovska's research articles have appeared predominantly in venues such as:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • Nature Cell Biology
  • PLoS Genetics

Best Publications

  • The Human Mitochondrial Transcriptome

    Tim R. Mercer;Shane Neph;Marcel E. Dinger;Joanna Crawford

  • Gold compounds as therapeutic agents for human diseases

    Susan J. Berners-Price;Aleksandra Filipovska

  • Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology.

    Meredith F Ross;Geoffrey Kelso;Frances H Blaikie;Andrew M James

  • Mitochondria-Targeted Chemotherapeutics: The Rational Design of Gold(I) N-Heterocyclic Carbene Complexes That Are Selectively Toxic to Cancer Cells and Target Protein Selenols in Preference to Thiols

    James L. Hickey;Rasha A. Ruhayel;Peter J. Barnard;Murray V. Baker

  • Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

    Oliver Rackham;Anne-Marie J. Shearwood;Tim R. Mercer;Stefan M.K. Davies

  • RNA processing in human mitochondria

    Maria I.G. Lopez Sanchez;Tim R. Mercer;Stefan M.K. Davies;Anne-Marie J. Shearwood

  • Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: potential role of CYS residues in decreasing oxidative damage.

    Thomas R. Hurd;Raquel Requejo;Aleksandra Filipovska;Stephanie Brown

  • Glutathionylation of Mitochondrial Proteins

    Thomas R. Hurd;Nikola J. Costa;Christina C. Dahm;Samantha M. Beer

  • A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: implications for anticancer therapeutics targeted to mitochondria.

    Oliver Rackham;Scott J. Nichols;Peter J. Leedman;Susan J. Berners-Price

  • Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

    Inge Kühl;Maria Miranda;Ilian Atanassov;Irina Kuznetsova

  • A universal code for RNA recognition by PUF proteins

    Aleksandra Filipovska;Muhammad F M Razif;Karoline K A Nygård;Oliver Rackham

  • Synthesis and Characterization of a Triphenylphosphonium-conjugated Peroxidase Mimetic INSIGHTS INTO THE INTERACTION OF EBSELEN WITH MITOCHONDRIA

    Aleksandra Filipovska;Geoffrey F. Kelso;Stephanie E. Brown;Samantha M. Beer

  • Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation

    Daniel M. Passon;Mihwa Lee;Oliver Rackham;Will A. Stanley

  • Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly

    Oliver Rackham;Jakob D. Busch;Stanka Matic;Stefan J. Siira

  • Mitochondria-targeted antioxidants in the treatment of disease.

    Robin A.J. Smith;Victoria J. Adlam;Frances H. Blaikie;Abdul-Rahman B. Manas

  • An artificial PPR scaffold for programmable RNA recognition

    Sandrine Claire Coquille;Aleksandra Filipovska;Tiongsun Chia;Lional Rajappa

  • Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors

    Oliver Rackham;Anne-Marie J. Shearwood;Ross Thyer;Elyshia McNamara

  • Cell-penetrating peptides do not cross mitochondrial membranes even when conjugated to a lipophilic cation: evidence against direct passage through phospholipid bilayers.

    Meredith F. Ross;Aleksandra Filipovska;Robin A. J. Smith;Michael J. Gait

  • Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation.

    Stefan M.K. Davies;Oliver Rackham;Anne-Marie J. Shearwood;Kristina L. Hamilton

  • POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA

    Inge Kühl;Maria Miranda;Viktor Posse;Dusanka Milenkovic

Frequent Co-Authors

Nils-Göran Larsson
Nils-Göran Larsson Karolinska Institute
Michael P. Murphy
Michael P. Murphy University of Cambridge
Susan J. Berners-Price
Susan J. Berners-Price Griffith University
Robin A. J. Smith
Robin A. J. Smith University of Otago
Tim R. Mercer
Tim R. Mercer Garvan Institute of Medical Research
David R. Thorburn
David R. Thorburn Murdoch Children's Research Institute
Mehul T. Dattani
Mehul T. Dattani University College London
James Whelan
James Whelan La Trobe University
John S. Mattick
John S. Mattick University of New South Wales
Christopher Semsarian
Christopher Semsarian University of Sydney

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