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Paola Parronchi

Paola Parronchi

D-Index & Metrics

Immunology

D-Index
58
Citations
21067
World Ranking
3461
National Ranking
131

Overview

Paola Parronchi is a researcher affiliated with the University of Florence in Italy. Their work primarily focuses on Medicine, with a significant emphasis on Immunology, Pulmonary and Respiratory Medicine, Rheumatology, Physiology, and Infectious Diseases. The research topics they cover include asthma and respiratory diseases, inflammasome and immune disorders, immunodeficiency and autoimmune disorders, COVID-19 clinical research studies, inflammatory myopathies and dermatomyositis, drug-induced adverse reactions, and SARS-CoV-2 and COVID-19 research.

Their publication record includes research appearing frequently in journals such as Allergy, Lara D. Veeken, Frontiers in Medicine, Annals of the Rheumatic Diseases, and Biomedicines. These venues reflect the interdisciplinary nature of their work intersecting clinical immunology, respiratory medicine, and autoimmune conditions.

Recent papers highlight significant investigations predominantly related to immune responses and respiratory diseases. Notable publications include:

  • Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent (2020, Journal of Clinical Investigation)
  • Is asthma protective against COVID-19? (2020, Allergy)
  • First-dose mRNA vaccination is sufficient to reactivate immunological memory to SARS-CoV-2 in subjects who have recovered from COVID-19 (2021, Journal of Clinical Investigation)
  • Prompt Predicting of Early Clinical Deterioration of Moderate-to-Severe COVID-19 Patients: Usefulness of a Combined Score Using IL-6 in a Preliminary Study (2020, The Journal of Allergy and Clinical Immunology In Practice)
  • Sex Differences in Severe Asthma: Results From Severe Asthma Network in Italy-SANI (2021, Allergy Asthma and Immunology Research)

Their research collaborations include frequent co-authors such as Giacomo Emmi, Lorenzo Salvati, Alessandra Vultaggio, Lorenzo Cosmi, and Giuseppe Lopalco. These partnerships reflect a multidisciplinary network contributing to advancing knowledge in immunology and pulmonary medicine.

Best Publications

  • Phenotypic and functional features of human Th17 cells.

    Francesco Annunziato;Lorenzo Cosmi;Veronica Santarlasci;Laura Maggi

  • Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

    R Manetti;P Parronchi;M G Giudizi;M P Piccinni

  • Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones.

    M P Piccinni;M G Giudizi;R Biagiotti;L Beloni

  • Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.

    Lorenzo Cosmi;Raffaele De Palma;Veronica Santarlasci;Laura Maggi

  • IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants.

    G Del Prete;E Maggi;P Parronchi;I Chrétien

  • Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones.

    E Maggi;P Parronchi;R Manetti;C Simonelli

  • Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production.

    Paola Parronchi;Donatella Macchia;Marie-Pierre Piccinni;Priscilla Biswas

  • Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease.

    P Parronchi;P Romagnani;F Annunziato;S Sampognaro

  • Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

    Francesco Liotta;Roberta Angeli;Lorenzo Cosmi;Lucia Filì

  • Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones.

    R Manetti;F Gerosa;M G Giudizi;R Biagiotti

  • IL-4 and IFN (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones.

    P Parronchi;M De Carli;R Manetti;C Simonelli

  • Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent.

    Alessio Mazzoni;Lorenzo Salvati;Laura Maggi;Manuela Capone

  • Accumulation of Th-2-like helper T cells in the conjunctiva of patients with vernal conjunctivitis.

    E Maggi;P Biswas;G Del Prete;P Parronchi

  • Th2-like CD8+ T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection.

    Enrico Maggi;Maria Grazia Giudizi;Roberta Biagiotti;Francesco Annunziato

  • Identification of a novel subset of human circulating memory CD4+ T cells that produce both IL-17A and IL-4

    Lorenzo Cosmi;Laura Maggi;Veronica Santarlasci;Manuela Capone

  • Anti‐infliximab IgE and non‐IgE antibodies and induction of infusion‐related severe anaphylactic reactions

    A. Vultaggio;A. Matucci;F. Nencini;S. Pratesi

  • Profiles of lymphokine activities and helper function for IgE in human T cell clones.

    Enrico Maggi;Gianfranco Del Prete;Donatella Macchia;Paola Parronchi

  • Aeroallergen Sensitization Can Occur during Fetal Life

    Piccinni Mp;Mecacci F;Sampognaro S;Manetti R

  • Identification of multiple T cell epitopes on Bet v I, the major birch pollen allergen, using specific T cell clones and overlapping peptides.

    C Ebner;Z Szépfalusi;F Ferreira;A Jilek

  • Polyinosinic acid: polycytidylic acid promotes T helper type 1‐specific immune responses by stimulating macrophage production of interferon‐α and interleukin‐12

    Roberto Manetti;Francesco Annunziato;Ljiljana Tomasevic;Valeria Giannò

Frequent Co-Authors

Enrico Maggi
Enrico Maggi Bambino Gesù Children's Hospital
Sergio Romagnani
Sergio Romagnani University of Florence
Francesco Annunziato
Francesco Annunziato University of Florence
Marie-Pierre Piccinni
Marie-Pierre Piccinni University of Florence
Roberto Manetti
Roberto Manetti University of Sassari
Laura Maggi
Laura Maggi Sapienza University of Rome
Lorenzo Cosmi
Lorenzo Cosmi University of Florence
Francesco Liotta
Francesco Liotta University of Florence
G. F. Del Prete
G. F. Del Prete University of Florence
Paola Romagnani
Paola Romagnani University of Florence

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