World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
20744
World Ranking
3751
National Ranking
75

Medicine

D-Index
82
Citations
20866
World Ranking
16292
National Ranking
644

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in Cancer research, Cell biology, Endocrinology, Internal medicine and Notch signaling pathway. His research in Cancer research intersects with topics in Tumor progression, Regulation of gene expression, Chromatin immunoprecipitation and Hedgehog signaling pathway. Alberto Gulino interconnects Thymocyte, Carcinogenesis, Transcription factor, Cell fate determination and Downregulation and upregulation in the investigation of issues within Cell biology.

His studies deal with areas such as Molecular biology, DNA damage and Phosphorylation as well as Transcription factor. His Endocrinology study integrates concerns from other disciplines, such as Growth factor and Gene expression. Internal medicine is closely attributed to Plasmin in his study.

His most cited work include:

  • Constitutive activation of NF‐κB and T‐cell leukemia/lymphoma in Notch3 transgenic mice (376 citations)
  • BRAF Mutations in Papillary Thyroid Carcinomas Inhibit Genes Involved in Iodine Metabolism (286 citations)
  • Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse (265 citations)

What are the main themes of his work throughout his whole career to date?

Alberto Gulino mainly investigates Cancer research, Internal medicine, Cell biology, Endocrinology and Molecular biology. His study in Cancer research is interdisciplinary in nature, drawing from both Genetics, Carcinogenesis, Transcription factor, Neuroblastoma and Regulation of gene expression. Alberto Gulino works mostly in the field of Internal medicine, limiting it down to topics relating to Oncology and, in certain cases, Breast cancer.

Within one scientific family, he focuses on topics pertaining to T cell under Cell biology, and may sometimes address concerns connected to T-cell leukemia. He combines topics linked to Gene expression with his work on Endocrinology. His Molecular biology research incorporates elements of Jurkat cells, Transcription, Transcriptional regulation, Transfection and Matrix metalloproteinase.

He most often published in these fields:

  • Cancer research (35.53%)
  • Internal medicine (26.32%)
  • Cell biology (24.12%)

What were the highlights of his more recent work (between 2009-2019)?

  • Cancer research (35.53%)
  • Cell biology (24.12%)
  • Carcinogenesis (8.33%)

In recent papers he was focusing on the following fields of study:

Alberto Gulino mainly focuses on Cancer research, Cell biology, Carcinogenesis, Molecular biology and Hedgehog. The study incorporates disciplines such as Cancer stem cell, Pathology, microRNA, Neuroblastoma and Regulation of gene expression in addition to Cancer research. The concepts of his Cell biology study are interwoven with issues in Receptor, HDAC1, Transcription factor and Medulloblastoma.

His Carcinogenesis research is multidisciplinary, incorporating elements of HDAC11, Histone deacetylase 2, HDAC10, Regulator and Ubiquitin ligase. His Molecular biology research includes elements of Response element, Transcription, Acetylation and Matrix metalloproteinase. The study incorporates disciplines such as Glycolysis and Hedgehog signaling pathway in addition to Hedgehog.

Between 2009 and 2019, his most popular works were:

  • Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy. (140 citations)
  • The multiple functions of Numb (138 citations)
  • MicroRNAs as biomarkers for CNS cancer and other disorders. (119 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His primary areas of study are Cancer research, Hedgehog, Hedgehog signaling pathway, Notch signaling pathway and Cancer stem cell. His Cancer research research is multidisciplinary, relying on both Smoothened, Carcinogenesis, Histone deacetylase, Histone and Molecular biology. His Hedgehog study necessitates a more in-depth grasp of Cell biology.

Alberto Gulino is interested in Signal transduction, which is a field of Cell biology. As a member of one scientific family, Alberto Gulino mostly works in the field of Hedgehog signaling pathway, focusing on Morphogen and, on occasion, Kinase, Cullin, Transcription factor and Ubiquitin. His study looks at the relationship between Notch signaling pathway and topics such as mir-223, which overlap with Gene silencing.

Best Publications

  • Constitutive activation of NF‐κB and T‐cell leukemia/lymphoma in Notch3 transgenic mice

    Diana Bellavia;Antonio F. Campese;Edoardo Alesse;Alessandra Vacca

  • Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice.

    I Screpanti;L Romani;P Musiani;A Modesti

  • BRAF Mutations in Papillary Thyroid Carcinomas Inhibit Genes Involved in Iodine Metabolism

    C. Durante;E. Puxeddu;E. Ferretti;R. Morisi

  • Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse

    F. Calcinaro;S. Dionisi;M. Marinaro;P. Candeloro

  • Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells

    Elisabetta Ferretti;Enrico De Smaele;Evelina Miele;Pietro Laneve

  • Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

    Gianluca Canettieri;Lucia Di Marcotullio;Azzura Greco;Sonia Coni

  • Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.

    Lucia Di Marcotullio;Elisabetta Ferretti;Azzura Greco;Enrico De Smaele

  • Angiotensin II Stimulates Intercellular Adhesion Molecule-1 (ICAM-1) Expression by Human Vascular Endothelial Cells and Increases Soluble ICAM-1 Release In Vivo

    L. Pastore;A. Tessitore;S. Martinotti;E. Toniato

  • MicroRNA profiling in human medulloblastoma

    Elisabetta Ferretti;Enrico De Smaele;Agnese Po;Lucia Di Marcotullio

  • Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements.

    Alessandra Vacca;Maria P. Felli;Antonietta R. Farina;Stefano Martinotti

  • Differential regulation of E2F1 apoptotic target genes in response to DNA damage

    Natalia Pediconi;Alessandra Ianari;Antonio Costanzo;Laura Belloni

  • Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy.

    Evelina Miele;Gian Paolo Spinelli;Ermanno Miele;Enzo Di Fabrizio

  • TrkA alternative splicing: A regulated tumor-promoting switch in human neuroblastoma

    Antonella Tacconelli;Antonietta R. Farina;Lucia Cappabianca;Giuseppina DeSantis

  • Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

    Diana Bellavia;Antonio F. Campese;Saula Checquolo;Anna Balestri

  • Immunizing and curative potential of replicating and nonreplicating murine mammary adenocarcinoma cells engineered with interleukin (IL)-2, IL-4, IL-6, IL-7, IL-10, tumor necrosis factor alpha, granulocyte-macrophage colony-stimulating factor, and gamma-interferon gene or admixed with conventional adjuvants.

    Alessandra Allione;Manuela Consalvo;Patrizia Nanni;Pier Luigi Lollini

  • Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand–receptor interactions in intrathymic T cell development

    Maria Pia Felli;Marella Maroder;Thimios A. Mitsiadis;Antonio F. Campese

  • Hedgehog controls neural stem cells through p53-independent regulation of Nanog

    Agnese Po;Elisabetta Ferretti;Evelina Miele;Enrico De Smaele

  • Steroid sensitivity of thymocyte subpopulations during intrathymic differentiation. Effects of 17 beta-estradiol and dexamethasone on subsets expressing T cell antigen receptor or IL-2 receptor.

    I Screpanti;S Morrone;D Meco;A Santoni

  • RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

    Lucia Di Marcotullio;Elisabetta Ferretti;Enrico De Smaele;Beatrice Argenti

  • The multiple functions of Numb

    Alberto Gulino;Lucia Di Marcotullio;Isabella Screpanti

Frequent Co-Authors

Isabella Screpanti
Isabella Screpanti Sapienza University of Rome
Luigi Frati
Luigi Frati Sapienza University of Rome
Elisabetta Ferretti
Elisabetta Ferretti Sapienza University of Rome
Felice Giangaspero
Felice Giangaspero Sapienza University of Rome
Andrea Modesti
Andrea Modesti University of Rome Tor Vergata
Angela Santoni
Angela Santoni Sapienza University of Rome
Giorgio Bernardi
Giorgio Bernardi University of Rome Tor Vergata
Paolo Calabresi
Paolo Calabresi Catholic University of the Sacred Heart
Diego Centonze
Diego Centonze University of Rome Tor Vergata
Sebastiano Filetti
Sebastiano Filetti Sapienza University of Rome

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