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Biology and Biochemistry

D-Index
60
Citations
13020
World Ranking
11945
National Ranking
349

Overview

Andrea Modesti is affiliated with the University of Rome Tor Vergata in Italy. Their research spans multiple fields within medicine and molecular biology, with a total of 14 publications related to Medicine and 8 related to Biochemistry, Genetics, and Molecular Biology. The subfields of study in which Modesti is involved include Molecular Biology, Oncology, Immunology, Epidemiology, and Orthopedics and Sports Medicine.

The primary topics of Modesti's research focus include ubiquitin and proteasome pathways, peptidase inhibition and analysis, glycosylation and glycoproteins research, cancer cells and metastasis, cell adhesion molecules research, phagocytosis and immune regulation, and COVID-19 clinical research studies.

Modesti has published in a range of scientific journals. Frequent publication venues include the International Journal of Molecular Sciences with two papers, Journal of Medical Virology, Scientific Reports, Pharmacology & Therapeutics, and Nutrients.

Among recently published papers associated with Modesti's research presence are:

  • Polyphenol-Mediated Autophagy in Cancer: Evidence of In Vitro and In Vivo Studies, 2020, International Journal of Molecular Sciences
  • SARS-COV-2 and infectivity: Possible increase in infectivity associated to integrin motif expression, 2020, Journal of Medical Virology
  • Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells, 2021, Scientific Reports
  • Infection by High-Risk Human Papillomaviruses, Epithelial-to-Mesenchymal Transition and Squamous Pre-Malignant or Malignant Lesions of the Uterine Cervix: A Series of Chained Events?, 2021, International Journal of Molecular Sciences
  • Targeting the tumor immune microenvironment with "nutraceuticals": From bench to clinical trials, 2020, Pharmacology & Therapeutics

Collaborative work features frequent co-authorship with several researchers, including Vittorio Manzari and Roberto Bei, each with seven joint publications, as well as Monica Benvenuto, Chiara Focaccetti, and Sara Ciuffa, each with six joint publications. This network reflects a collaborative approach to advancing understanding in their fields of interest.

Best Publications

  • The intriguing role of polymorphonuclear neutrophils in antitumor reactions.

    Emma Di Carlo;Guido Forni;PierLuigi Lollini;Mario P. Colombo

  • Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice.

    I Screpanti;L Romani;P Musiani;A Modesti

  • Interleukin 12–mediated Prevention of Spontaneous Mammary Adenocarcinomas in Two Lines of Her-2/neu Transgenic Mice

    Katia Boggio;Giordano Nicoletti;Emma Di Carlo;Federica Cavallo

  • Effects of vitamin C on health: a review of evidence.

    Giuseppe Grosso;Roberto Bei;Antonio Mistretta;Stefano Marventano

  • In vitro and in vivo antitumoral effects of combinations of polyphenols, or polyphenols and anticancer drugs: perspectives on cancer treatment

    Massimo Fantini;Monica Benvenuto;Laura Masuelli;Giovanni Vanni Frajese

  • Role of neutrophils and CD4+ T lymphocytes in the primary and memory response to nonimmunogenic murine mammary adenocarcinoma made immunogenic by IL-2 gene.

    Federica Cavallo;Mirella Giovarelli;Alberto Gulino;Alessandra Vacca

  • Local release of IL-10 by transfected mouse mammary adenocarcinoma cells does not suppress but enhances antitumor reaction and elicits a strong cytotoxic lymphocyte and antibody-dependent immune memory.

    M Giovarelli;P Musiani;A Modesti;P Dellabona

  • Local cytokine availability elicits tumor rejection and systemic immunity through granulocyte-T-lymphocyte cross-talk.

    Mario P. Colombo;Andrea Modesti;Giorgio Parmiani;Guido Forni

  • The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the α5β1 and αvβ3 integrins and by mobilizing sequestered basic fibroblast growth factor

    Giovanni Barillari;Cecilia Sgadari;Valeria Fiorelli;Felipe Samaniego

  • CYTOKINES, TUMOUR-CELL DEATH AND IMMUNOGENICITY : A QUESTION OF CHOICE

    Piero Musiani;Andrea Modesti;Mirella Giovarelli;Federica Cavallo

  • RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

    Lucia Di Marcotullio;Elisabetta Ferretti;Enrico De Smaele;Beatrice Argenti

  • IL‐6 Expression in Neurons of Transgenic Mice Causes Reactive Astrocytosis and Increase in Ramified Microglial Cells but no Neuronal Damage

    Elena Fattori;Domenico Lazzaro;Piero Musiani;Andrea Modesti

  • Antitumor efficacy of adenocarcinoma cells engineered to produce interleukin 12 (IL-12) or other cytokines compared with exogenous IL-12.

    Federica Cavallo;Paola Signorelli;Mirella Giovarelli;Piero Musiani

  • IFN-alpha 1 gene expression into a metastatic murine adenocarcinoma (TS/A) results in CD8+ T cell-mediated tumor rejection and development of antitumor immunity. Comparative studies with IFN-gamma-producing TS/A cells.

    M Ferrantini;M Giovarelli;A Modesti;P Musiani

  • Coexpression of IL‐6 and soluble IL‐6R causes nodular regenerative hyperplasia and adenomas of the liver

    Domenico Maione;Emma Di Carlo;Wei Li;Piero Musiani

  • Dietary flavonoids: molecular mechanisms of action as anti- inflammatory agents.

    Laura Marzocchella;Massimo Fantini;Monica Benvenuto;Laura Masuelli

  • The effects of dietary flavonoids on the regulation of redox inflammatory networks.

    Izzi;Masuelli L;Tresoldi I;Sacchetti P

  • An efficient Th2-type memory follows CD8+ lymphocyte-driven and eosinophil-mediated rejection of a spontaneous mouse mammary adenocarcinoma engineered to release IL-4.

    F Pericle;M Giovarelli;M P Colombo;G Ferrari

  • Group B streptococci persist inside macrophages

    Paola Cornacchione;Lucia Scaringi;Katia Fettucciari;Emanuela Rosati

  • HTLV-V: a new human retrovirus isolated in a Tac-negative T cell lymphoma/leukemia.

    Vittorio Manzari;Angela Gismondi;Giovanni Barillari;Stefania Morrone

Frequent Co-Authors

Piero Musiani
Piero Musiani University of Chieti-Pescara
Guido Forni
Guido Forni University of Turin
Mirella Giovarelli
Mirella Giovarelli University of Turin
Massimo Fantini
Massimo Fantini Precision Biologics
Federica Cavallo
Federica Cavallo University of Turin
Isabella Screpanti
Isabella Screpanti Sapienza University of Rome
Luigi Frati
Luigi Frati Sapienza University of Rome
Alberto Gulino
Alberto Gulino Sapienza University of Rome
Mario P. Colombo
Mario P. Colombo Fondazione IRCCS Istituto Nazionale dei Tumori
Emma Di Carlo
Emma Di Carlo University of Chieti-Pescara

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