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Biology and Biochemistry

D-Index
69
Citations
15717
World Ranking
7457
National Ranking
3398

Overview

David S. Lawrence is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans several subfields, including Molecular Biology, Materials Chemistry, Cellular and Molecular Neuroscience, Biomedical Engineering, and Organic Chemistry.

The main topics of Lawrence's scientific work include:

  • Photoreceptor and optogenetics research
  • Photochromic and fluorescence chemistry
  • Chemical safety and risk management
  • Bioluminescence and chemiluminescence research
  • Ubiquitin and proteasome pathways
  • Light effects on plants
  • Nanoplatforms for cancer theranostics

They have contributed to multiple publications, with recent papers covering advances in phototherapeutics, light-controlled protein release, and laboratory safety training. Selected recent works include:

  • Taking phototherapeutics from concept to clinical launch, 2021, Nature Reviews Chemistry
  • Light-Controlled Release of Therapeutic Proteins from Red Blood Cells, 2020, ACS Central Science
  • Virtually Bridging the Safety Gap between the Lecture Hall and the Research Laboratory, 2022, Journal of Chemical Education
  • Light-Triggered Drug Release from Red Blood Cells Suppresses Arthritic Inflammation, 2021, Advanced Therapeutics
  • An Assessment of Laboratory Safety Training in Undergraduate Education, 2024, Journal of Chemical Education

Frequent collaborators with Lawrence include Lauren Haar, Brianna M. Vickerman, Qunzhao Wang, Melanie A. Priestman, and Joshua G. Welfare. Their work has been published in venues such as UNC Libraries, OPAL (Open@LaTrobe) at La Trobe University, Journal of Chemical Education, The FASEB Journal, and Nature Reviews Chemistry.

Best Publications

  • Self-Assembling Supramolecular Complexes

    David S. Lawrence;Tao. Jiang;Michael. Levett

  • Frequency of Prolonged Remission Duration after High-Dose Cytarabine Intensification in Acute Myeloid Leukemia Varies by Cytogenetic Subtype

    Clara D. Bloomfield;David Lawrence;John C. Byrd;Andrew Carroll

  • Cofilin Promotes Actin Polymerization and Defines the Direction of Cell Motility

    Mousumi Ghosh;Xiaoyan Song;Ghassan Mouneimne;Mazen Sidani

  • Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: A paradigm for inhibitor design

    Yoram A. Puius;Yu Zhao;Michael Sullivan;Michael Sullivan;David S. Lawrence

  • Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds.

    Hsien Ming Lee;Daniel R. Larson;David S. Lawrence

  • Synergies and coincidence requirements between NO, cGMP, and Ca2+ in the induction of cerebellar long-term depression.

    Varda Lev-Ram;Tao Jiang;Jason Wood;David S Lawrence

  • Chemical Mutation of Enzyme Active Sites

    E. T. Kaiser;D. S. Lawrence

  • PROTEIN KINASE INHIBITORS : THE TYROSINE-SPECIFIC PROTEIN KINASES

    David S. Lawrence;Jinkui Niu

  • Extramedullary leukemia adversely affects hematologic complete remission rate and overall survival in patients with t(8;21)(q22;q22): results from Cancer and Leukemia Group B 8461.

    J C Byrd;R B Weiss;D C Arthur;D Lawrence

  • Phosphorylation of Adf/Cofilin Abolishes Egf-Induced Actin Nucleation at the Leading Edge and Subsequent Lamellipod Extension

    Noureddine Zebda;Ora Bernard;Maryse Bailly;Susan Welti

  • Acquisition of a Specific and Potent PTP1B Inhibitor from a Novel Combinatorial Library and Screening Procedure

    Kui Shen;Yen Fang Keng;Li Wu;Xiao Ling Guo

  • Rearrangement of ALL1 (MLL) in Acute Myeloid Leukemia with Normal Cytogenetics

    Michael A. Caligiuri;Matthew P. Strout;David Lawrence;Diane C. Arthur

  • Presynaptic role of cGMP-dependent protein kinase during long-lasting potentiation

    Ottavio Arancio;Irina Antonova;Stepan Gambaryan;Suzanne M. Lohmann

  • APRIL-Deficient Mice Have Normal Immune System Development

    Eugene Varfolomeev;Frank Kischkel;Flavius Martin;Dhaya Seshasayee

  • Lamellipodia in invasion

    John S. Condeelis;Jeffrey B. Wyckoff;Maryse Bailly;Richard Pestell

  • Definition of Optimal Substrate Recognition Motifs of Ca2+-Calmodulin-dependent Protein Kinases IV and II Reveals Shared and Distinctive Features

    Ronald R. White;Young Guen Kwon;Meng Taing;David Scott Lawrence

  • Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor

    Jin Peng Sun;Alexander A. Fedorov;Seung Yub Lee;Xiao Ling Guo

  • Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.

    Mauro Sarmiento;Yoram A. Puius;Stefan W. Vetter;Yen Fang Keng

  • Structural genomics of protein phosphatases

    Steven C. Almo;Jeffrey B. Bonanno;J. Michael Sauder;Spencer Emtage

  • Template-driven self-assembly of a porphyrin-containing supramolecular complex

    John S. Manka;David S. Lawrence

Frequent Co-Authors

Zhong Yin Zhang
Zhong Yin Zhang Purdue University West Lafayette
Nancy L. Allbritton
Nancy L. Allbritton University of Washington
John S. Condeelis
John S. Condeelis Albert Einstein College of Medicine
Clara D. Bloomfield
Clara D. Bloomfield The Ohio State University
Diane C. Arthur
Diane C. Arthur National Institutes of Health
Robert H. Singer
Robert H. Singer Albert Einstein College of Medicine
Jackie D. Corbin
Jackie D. Corbin Vanderbilt University
Sharron H. Francis
Sharron H. Francis Vanderbilt University
Steven C. Almo
Steven C. Almo Albert Einstein College of Medicine
Charles A. Schiffer
Charles A. Schiffer Wayne State University

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