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Heinrich Jasper

Heinrich Jasper

D-Index & Metrics

Molecular Biology

D-Index
60
Citations
13353
World Ranking
1958
National Ranking
974

Overview

Heinrich Jasper is affiliated with Genentech in the United States and has contributed extensively to fields intersecting biochemistry, genetics, molecular biology, and medicine. Their research addresses multiple subfields including molecular biology, immunology, cellular and molecular neuroscience, insect science, and epidemiology.

Their work covers a range of research topics such as:

  • Invertebrate Immune Response Mechanisms
  • Neurobiology and Insect Physiology Research
  • Autophagy in Disease and Therapy
  • Genetics, Aging, and Longevity in Model Organisms
  • Epigenetics and DNA Methylation
  • Developmental Biology and Gene Regulation
  • Insect symbiosis and bacterial influences

Heinrich Jasper's recent publications include studies published in highly regarded journals with wide citation ranges. Notable papers are:

  • "Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly," 2022, Science
  • "Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury," 2021, Redox Biology
  • "In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice," 2022, Nature Aging
  • "Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution," 2023, Science
  • "Fly Cell Atlas: a single-cell transcriptomic atlas of the adult fruit fly," 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators contributing alongside Heinrich Jasper include:

  • Nadja Sandra Katheder
  • Hongjie Li
  • Liqun Luo
  • Xiaoyu Cai
  • Kristen Browder

The scientist has published regularly in several venues, with the highest number of works appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • eLife
  • Science
  • Redox Biology

Best Publications

  • JNK Extends Life Span and Limits Growth by Antagonizing Cellular and Organism-Wide Responses to Insulin Signaling

    Meng C. Wang;Dirk Bohmann;Heinrich Jasper

  • JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut

    Benoît Biteau;Christine E. Hochmuth;Heinrich Jasper

  • JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila

    Meng C. Wang;Dirk Bohmann;Heinrich Jasper

  • PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan

    Linlin Guo;Jason Karpac;Susan L. Tran;Heinrich Jasper;Heinrich Jasper

  • Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila.

    Christine E. Hochmuth;Benoit Biteau;Dirk Bohmann;Heinrich Jasper

  • Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila

    Benoît Biteau;Jason Karpac;Stephen Supoyo;Matthew DeGennaro

  • Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster

    Irene Miguel-Aliaga;Heinrich Jasper;Heinrich Jasper;Bruno Lemaitre

  • Maintaining tissue homeostasis: dynamic control of somatic stem cell activity.

    Benoit Biteau;Christine E. Hochmuth;Heinrich Jasper

  • EGF signaling regulates the proliferation of intestinal stem cells in Drosophila

    Benoît Biteau;Heinrich Jasper

  • Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing.

    Navdeep S. Chandel;Heinrich Jasper;Theodore T. Ho;Emmanuelle Passegué

  • SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements

    Oliver Nayler;Wolf Strätling;Jean-Pierre Bourquin;Igor Stagljar

  • Immune modulation by MANF promotes tissue repair and regenerative success in the retina.

    Joana Neves;Jie Zhu;Pedro Sousa-Victor;Mia Konjikusic

  • Preventing Age-Related Decline of Gut Compartmentalization Limits Microbiota Dysbiosis and Extends Lifespan.

    Hongjie Li;Yanyan Qi;Heinrich Jasper;Heinrich Jasper

  • NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome.

    Evandro F. Fang;Yujun Hou;Sofie Lautrup;Martin Borch Jensen

  • Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury

    Martin D. Brand;Renata L.S. Goncalves;Adam L. Orr;Leonardo Vargas

  • Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer

    Peter D. Adams;Heinrich Jasper;K. Lenhard Rudolph

  • Slit/Robo signaling regulates cell fate decisions in the intestinal stem cell lineage of Drosophila.

    Benoît Biteau;Heinrich Jasper

  • Signal integration by Ca 2+ regulates intestinal stem-cell activity

    Hansong Deng;Akos A. Gerencser;Heinrich Jasper

  • Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model.

    Mirka Uhlirova;Heinrich Jasper;Dirk Bohmann

  • Mitochondrial proteostasis in the control of aging and longevity

    Martin Borch Jensen;Heinrich Jasper

Frequent Co-Authors

Dirk Bohmann
Dirk Bohmann University of Rochester Medical Center
Pankaj Kapahi
Pankaj Kapahi Buck Institute for Research on Aging
Thomas A. Rando
Thomas A. Rando Stanford University
Zora Modrusan
Zora Modrusan Genentech
Amit Sharma
Amit Sharma Microsoft (United States)
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Judith Campisi
Judith Campisi Buck Institute for Research on Aging
Vladimir Benes
Vladimir Benes European Molecular Biology Laboratory
Brian K. Kennedy
Brian K. Kennedy National University of Singapore
Nils-Göran Larsson
Nils-Göran Larsson Karolinska Institute

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