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Biology and Biochemistry

D-Index
117
Citations
56254
World Ranking
716
National Ranking
455

Overview

Martin D. Brand is affiliated with the Buck Institute for Research on Aging in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a total of 31 publications in these fields. Additionally, they have contributed to the field of medicine, producing 20 publications related to that discipline. Subfields of interest include molecular biology, physiology, immunology, emergency medicine, and public health, environmental and occupational health.

The scientist's work covers various topics related to mitochondrial function and pathology, with 26 publications in this area. Other prominent topics include adipose tissue and metabolism, ATP synthase and ATPases research, Coenzyme Q10 studies and effects, redox biology and oxidative stress, nitric oxide and endothelin effects, and ion channel regulation and function.

Frequent publication venues for Martin D. Brand's research include:

  • Free Radical Biology and Medicine
  • Transplantation
  • SSRN Electronic Journal
  • Critical Reviews in Biochemistry and Molecular Biology
  • Redox Biology

Frequent co-authors collaborating with Martin D. Brand are:

  • Mark A. Watson
  • Timothy Craig Hardcastle
  • Hoi Shan Wong
  • Akos A. Gerencser
  • Bijoya Sen

Some of the recent papers authored or co-authored by Martin D. Brand include:

  • "Riding the tiger - physiological and pathological effects of superoxide and hydrogen peroxide generated in the mitochondrial matrix," published in 2020 in Critical Reviews in Biochemistry and Molecular Biology
  • "Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site IQ of complex I in diverse cell lines," published in 2020 in Redox Biology
  • "Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H2O2 production in heart and skeletal muscle mitochondria," published in 2020 in FEBS Letters
  • "A critical assessment of the role of creatine in brown adipose tissue thermogenesis," published in 2023 in Nature Metabolism
  • "Site IQ in mitochondrial complex I generates S1QEL-sensitive superoxide/hydrogen peroxide in both the reverse and forward reactions," published in 2023 in Biochemical Journal

Best Publications

  • Assessing mitochondrial dysfunction in cells

    Martin D. Brand;David G. Nicholls

  • Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain

    Julie St-Pierre;Julie A. Buckingham;Stephen J. Roebuck;Martin D. Brand

  • Superoxide activates mitochondrial uncoupling proteins

    Karim S. Echtay;Damien Roussel;Julie St-Pierre;Mika B. Jekabsons

  • The sites and topology of mitochondrial superoxide production

    Martin D. Brand

  • Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins.

    Martin D Brand;Charles Affourtit;Telma C Esteves;Katherine Green

  • Uncoupling to survive? The role of mitochondrial inefficiency in ageing.

    M.D Brand

  • Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

    Martin D. Brand

  • Mitofusin-2 Determines Mitochondrial Network Architecture and Mitochondrial Metabolism A NOVEL REGULATORY MECHANISM ALTERED IN OBESITY

    Daniel Bach;Sara Pich;Francesc X. Soriano;Nathalie Vega

  • A hierarchy of ATP-consuming processes in mammalian cells.

    F Buttgereit;M D Brand

  • Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3

    Martin D. Brand;Telma C. Esteves

  • Mitochondrial proton and electron leaks

    Martin Jastroch;Ajit S. Divakaruni;Shona Mookerjee;Jason R. Treberg

  • Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean

    John C. Clapham;Jonathan R. S. Arch;Helen Chapman;Andrea Haynes

  • Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes.

    Katherine Green;Martin D. Brand;Michael P. Murphy

  • Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

    Casey L. Quinlan;Adam L. Orr;Irina V. Perevoshchikova;Jason R. Treberg

  • A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling

    Karim S. Echtay;Telma C. Esteves;Julian L. Pakay;Mika B. Jekabsons

  • The causes and functions of mitochondrial proton leak

    Martin D. Brand;Lee-Feng Chien;Edward K. Ainscow;David F.S. Rolfe

  • Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

    Casey L. Quinlan;Irina V. Perevoshchikova;Martin Hey-Mogensen;Martin Hey-Mogensen;Adam L. Orr

  • Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer

    John R. Speakman;John R. Speakman;Darren A. Talbot;Colin Selman;Sam Snart

  • Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane

    Adrian J. Lambert;Martin D. Brand

  • Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).

    Adrian J. Lambert;Martin D. Brand

Frequent Co-Authors

David G. Nicholls
David G. Nicholls Buck Institute for Research on Aging
Guy C. Brown
Guy C. Brown University of Cambridge
Michael P. Murphy
Michael P. Murphy University of Cambridge
Frank Buttgereit
Frank Buttgereit Charité - University Medicine Berlin
Martin Jastroch
Martin Jastroch Stockholm University
Antonio Vidal-Puig
Antonio Vidal-Puig University of Cambridge
Mary-Ellen Harper
Mary-Ellen Harper University of Ottawa
Kevin M. Brindle
Kevin M. Brindle University of Cambridge
Linda Partridge
Linda Partridge Max Planck Society
Paul S. Brookes
Paul S. Brookes University of Rochester Medical Center

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