The scientist’s investigation covers issues in Mitochondrion, Biochemistry, Membrane potential, Glutamate receptor and Biophysics. To a larger extent, David G. Nicholls studies Cell biology with the aim of understanding Mitochondrion. His studies in Biochemistry integrate themes in fields like Calcium and Respiration.
His Membrane potential research is multidisciplinary, incorporating perspectives in Respiratory chain, Electron transport chain, Electrochemical gradient and Efflux. His study in Glutamate receptor is interdisciplinary in nature, drawing from both Neurotransmitter, Extracellular, Exocytosis, Glutamic acid and Synaptosome. His Biophysics research incorporates themes from Calcium metabolism, Phosphate, Intracellular and Ion transporter.
David G. Nicholls mainly focuses on Mitochondrion, Biochemistry, Biophysics, Cell biology and Glutamate receptor. His work carried out in the field of Mitochondrion brings together such families of science as Excitotoxicity, Brown adipose tissue, ATP synthase and Membrane potential. In his study, which falls under the umbrella issue of Biochemistry, Cytosol and Membrane transport is strongly linked to Calcium.
The concepts of his Biophysics study are interwoven with issues in Guinea pig, Exocytosis, Membrane and Electron transport chain. His Cell biology research incorporates elements of Apoptosis, Uniporter and Oligomycin. His Glutamate receptor research includes themes of NMDA receptor, Neurotransmitter, Neuroprotection and Glutamic acid.
David G. Nicholls spends much of his time researching Mitochondrion, Cell biology, Biochemistry, Biophysics and Bioenergetics. Inner mitochondrial membrane is the focus of his Mitochondrion research. The Cell biology study combines topics in areas such as Excitotoxicity, Uniporter, Cytosol and Neuron.
In his study, Warburg effect and In vivo is inextricably linked to Respiration, which falls within the broad field of Biochemistry. David G. Nicholls mostly deals with Membrane potential in his studies of Biophysics. David G. Nicholls works mostly in the field of Bioenergetics, limiting it down to topics relating to Glutamate receptor and, in certain cases, Potassium channel, Ex vivo and Synaptosome, as a part of the same area of interest.
His primary areas of study are Mitochondrion, Glycolysis, Biochemistry, Extracellular and Membrane potential. His specific area of interest is Mitochondrion, where David G. Nicholls studies Bioenergetics. His Glycolysis research integrates issues from Oxidative phosphorylation and Insulin.
His research investigates the link between Biochemistry and topics such as Respiration that cross with problems in In vivo. Membrane potential is the subject of his research, which falls under Biophysics. His work in Biophysics covers topics such as Electron transport chain which are related to areas like Chemiosmosis, ATP synthase and Respiration rate.
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Assessing mitochondrial dysfunction in cells
Martin D. Brand;David G. Nicholls.
Biochemical Journal (2011)
Thermogenic mechanisms in brown fat.
D G Nicholls;R M Locke.
Physiological Reviews (1984)
Mitochondria and Neuronal Survival
David G. Nicholls;Samantha L. Budd.
Physiological Reviews (2000)
The release and uptake of excitatory amino acids.
David Nicholls;David Attwell.
Trends in Pharmacological Sciences (1990)
Mitochondrial calcium transport.
David Nicholls;Karl Åkerman.
Biochimica et Biophysica Acta (1982)
The Influence of Respiration and ATP Hydrolysis on the Proton‐Electrochemical Gradient across the Inner Membrane of Rat‐Liver Mitochondria as Determined by Ion Distribution
David G. Nicholls.
FEBS Journal (1974)
Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts.
David G. Nicholls;Manus W. Ward.
Trends in Neurosciences (2000)
Mitochondria, Calcium Regulation, and Acute Glutamate Excitotoxicity in Cultured Cerebellar Granule Cells
Samantha L. Budd;David G. Nicholls.
Journal of Neurochemistry (2002)
Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria
Brian M. Polster;Brian M. Polster;Gorka Basañez;Aitor Etxebarria;J. Marie Hardwick.
Journal of Biological Chemistry (2005)
Calcium-Dependent and-Independent Release of Glutamate from Synaptosomes Monitored by Continuous Fluorometry
David G. Nicholls;Talvinder S. Sihra;Jose Sanchez-Prieto.
Journal of Neurochemistry (1987)
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