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Biology and Biochemistry

D-Index
111
Citations
42840
World Ranking
940
National Ranking
587

Overview

David G. Nicholls is affiliated with the Buck Institute for Research on Aging in the United States. Their research spans multiple disciplines including Environmental Science and Biochemistry, Genetics and Molecular Biology. Nicholls has contributed to both broad and specialized topics within these fields, with notable focus areas being mitochondrial function and pathology, adipose tissue and metabolism, muscle metabolism and nutrition, avian ecology and behavior, wildlife ecology and conservation, marine animal studies, and species distribution in the context of climate change.

Among Nicholls' recent publications are the following:

  • Mitochondrial proton leaks and uncoupling proteins, 2021, Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • A framework for mapping the distribution of seabirds by integrating tracking, demography and phenology, 2020, Journal of Applied Ecology
  • Global political responsibility for the conservation of albatrosses and large petrels, 2021, Science Advances
  • A critical assessment of the role of creatine in brown adipose tissue thermogenesis, 2023, Nature Metabolism
  • Mitochondrial clearance of calcium facilitated by MICU2 controls insulin secretion, 2021, Molecular Metabolism

David G. Nicholls has frequently published in the following venues:

  • Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • The Science of The Total Environment
  • Journal of Applied Ecology
  • Science Advances
  • Nature Metabolism

Frequent co-authors collaborating with Nicholls include:

  • Thomas A. Clay
  • Peter G. Ryan
  • Javier A. Arata
  • Elizabeth Bell
  • Paulo Catry

The scientific subfields in which Nicholls is active include ecology, molecular biology, physiology, cell biology, and astronomy and astrophysics. This diverse set of subfields reflects a multidisciplinary approach to research.

Their main topics of work focus on:

  • Mitochondrial Function and Pathology
  • Adipose Tissue and Metabolism
  • Muscle metabolism and nutrition
  • Avian ecology and behavior
  • Wildlife Ecology and Conservation
  • Marine animal studies overview
  • Species Distribution and Climate Change

Best Publications

  • Assessing mitochondrial dysfunction in cells

    Martin D. Brand;David G. Nicholls

  • Thermogenic mechanisms in brown fat.

    D G Nicholls;R M Locke

  • Mitochondria and Neuronal Survival

    David G. Nicholls;Samantha L. Budd

  • The release and uptake of excitatory amino acids.

    David Nicholls;David Attwell

  • Mitochondrial calcium transport.

    David Nicholls;Karl Åkerman

  • The Influence of Respiration and ATP Hydrolysis on the Proton‐Electrochemical Gradient across the Inner Membrane of Rat‐Liver Mitochondria as Determined by Ion Distribution

    David G. Nicholls

  • Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts.

    David G. Nicholls;Manus W. Ward

  • Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria

    Brian M. Polster;Brian M. Polster;Gorka Basañez;Aitor Etxebarria;J. Marie Hardwick

  • Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells.

    Samantha L. Budd;David G. Nicholls

  • Calcium-Dependent and-Independent Release of Glutamate from Synaptosomes Monitored by Continuous Fluorometry

    David G. Nicholls;Talvinder S. Sihra;Jose Sanchez-Prieto

  • Brown-Adipose-Tissue Mitochondria: Photoaffinity Labelling of the Regulatory Site of Energy Dissipation

    Gillian M. Heaton;Rob J. Wagenvoord;Albertus Kemp;David G. Nicholls

  • Brown adipose tissue mitochondria

    David G. Nicholls

  • Differential release of amino acids, neuropeptides, and catecholamines from isolated nerve terminals.

    Matthijs Verhage;Harvey T. McMahon;Wim E.J.M. Ghijsen;Frans. Boomsma

  • The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria.

    David G. Nicholls

  • Release of Glutamate, Aspartate, and γ‐Aminobutyric Acid from Isolated Nerve Terminals

    David G. Nicholls

  • Energy transduction in intact synaptosomes. Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ.

    I D Scott;D G Nicholls

  • Mitochondrial membrane potential and aging

    David G. Nicholls

  • Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements

    Shona A. Mookerjee;Shona A. Mookerjee;Akos A. Gerencser;David G. Nicholls;Martin D. Brand;Martin D. Brand

  • Synaptosomes possess an exocytotic pool of glutamate

    David G. Nicholls;Talvinder S. Sihra

  • Intracellular calcium homeostasis.

    D G Nicholls

Frequent Co-Authors

Harvey T. McMahon
Harvey T. McMahon MRC Laboratory of Molecular Biology
Martin D. Brand
Martin D. Brand Buck Institute for Research on Aging
Hindrik Mulder
Hindrik Mulder Lund University
Julie K. Andersen
Julie K. Andersen Buck Institute for Research on Aging
Roger F. Castilho
Roger F. Castilho State University of Campinas
Paolo Bernardi
Paolo Bernardi University of Padua
Andrew P. Halestrap
Andrew P. Halestrap University of Bristol
A. Cristina Rego
A. Cristina Rego University of Coimbra
Karl E. O. Åkerman
Karl E. O. Åkerman University of Helsinki
Jeremy J. Lambert
Jeremy J. Lambert University of Dundee

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