Karl E. O. Åkerman

What is he best known for?

The fields of study he is best known for:

• Enzyme
• Biochemistry
• Amino acid

Karl E.O. Åkerman mainly investigates Cell biology, Biophysics, Mitochondrion, Protein kinase C and Receptor. Karl E.O. Åkerman studies MAPK/ERK pathway, a branch of Cell biology. Karl E.O. Åkerman studies Membrane potential which is a part of Biophysics.

His research investigates the connection with Mitochondrion and areas like Calcium which intersect with concerns in Bioenergetics. His research integrates issues of Gs alpha subunit and Phospholipase C in his study of Protein kinase C. Receptor is a primary field of his research addressed under Biochemistry.

His most cited work include:

• Safranine as a probe of the mitochondrial membrane potential (677 citations)
• Mitochondrial calcium transport. (434 citations)
• Functions of the orexinergic/hypocretinergic system (246 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cell biology, Biochemistry, Receptor, Internal medicine and Endocrinology. His Cell biology research includes elements of Metabotropic glutamate receptor 5 and Transient receptor potential channel. His study in the field of Muscarinic acetylcholine receptor, Mitochondrion, Peptide and Ionophore is also linked to topics like Glomus cell.

His studies deal with areas such as Molecular biology, Pharmacology and Intracellular as well as Receptor. His Internal medicine study combines topics in areas such as Extracellular and Biophysics. His Biophysics research is multidisciplinary, relying on both EGTA and Membrane.

He most often published in these fields:

• Cell biology (42.16%)
• Biochemistry (37.30%)
• Receptor (32.97%)

What were the highlights of his more recent work (between 2009-2020)?

• Cell biology (42.16%)
• Biochemistry (37.30%)
• Receptor (32.97%)

In recent papers he was focusing on the following fields of study:

Karl E.O. Åkerman spends much of his time researching Cell biology, Biochemistry, Receptor, Neuroscience and Neural stem cell. In the subject of general Cell biology, his work in Intracellular pH is often linked to Neurosphere, thereby combining diverse domains of study. His work in the fields of Extracellular and Secretion overlaps with other areas such as Proinflammatory cytokine.

Karl E.O. Åkerman combines subjects such as Rous sarcoma virus and Molecular biology with his study of Receptor. His work on Hippocampus as part of his general Neuroscience study is frequently connected to FMR1, thereby bridging the divide between different branches of science. His G protein-coupled receptor research incorporates elements of Muscarinic acetylcholine receptor, Protein kinase A, Orexin receptor, Protein kinase C and Neuregulin.

Between 2009 and 2020, his most popular works were:

• Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome (178 citations)
• Inhibiting TRPA1 ion channel reduces loss of cutaneous nerve fiber function in diabetic animals: sustained activation of the TRPA1 channel contributes to the pathogenesis of peripheral diabetic neuropathy. (82 citations)
• BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse. (62 citations)

In his most recent research, the most cited papers focused on:

• Enzyme
• Biochemistry
• Amino acid

Cell biology, Neuroscience, Biochemistry, FMR1 and Hippocampus are his primary areas of study. His work deals with themes such as TRPC Cation Channels and TRPC, which intersect with Cell biology. The study incorporates disciplines such as Metabotropic glutamate receptor 5, Metabotropic glutamate receptor, Long-term depression and Kainate receptor in addition to Neuroscience.

Biochemistry is frequently linked to T-type calcium channel in his study. His biological study spans a wide range of topics, including Hippocampal formation, Knockout mouse and Fragile X syndrome. Karl E.O. Åkerman interconnects Extracellular, Calpain, Caspase 1 and Unconventional protein secretion in the investigation of issues within Innate immune system.