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Medicine

D-Index
83
Citations
22529
World Ranking
15730
National Ranking
510

Overview

Philippe Valet is affiliated with Paul Sabatier University in France and has contributed to the field of medicine with a focus on physiology, cardiology and cardiovascular medicine, pharmacology, oncology, and molecular biology. Their research spans a variety of topics including apelin-related biomedical research, lipid metabolism and disorders, genetics and aging in model organisms, cardiovascular neuropeptides and oxidative stress research, adipose tissue and metabolism, nutrition and health in aging, and frailty in older adults.

Recent notable publications by Philippe Valet include:

  • Adipocyte extracellular vesicles carry enzymes and fatty acids that stimulate mitochondrial metabolism and remodeling in tumor cells, 2020, The EMBO Journal
  • Human Bone Marrow Is Comprised of Adipocytes with Specific Lipid Metabolism, 2020, Cell Reports
  • Revisiting the Hallmarks of Aging to Identify Markers of Biological Age, 2020, The Journal of Prevention of Alzheimer s Disease
  • Adipocyte Fatty Acid Transfer Supports Megakaryocyte Maturation, 2020, Cell Reports
  • SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations, 2021, Science Translational Medicine

Philippe Valet has frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, The Journal of Frailty & Aging, The Journals of Gerontology Series A, and Molecular and Cellular Endocrinology.

The scientist has collaborated regularly with several co-authors, including:

  • Cédric Dray
  • Sophie Guyonnet
  • Sandrine Andrieu
  • Philipe de Souto Barreto
  • Angelo Parini

The overall body of work addresses complex biological processes related to aging, metabolism, and disease mechanisms. With 81 publications classified under medicine and diverse subfields, Philippe Valet's research intersects critical aspects of health spanning from cellular metabolism to clinical implications in aging and frailty.

Best Publications

  • Apelin, a newly identified adipokine up-regulated by insulin and obesity

    Jérémie Boucher;Bernard Masri;Danièle Daviaud;Stéphane Gesta

  • Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion

    Béatrice Dirat;Ludivine Bochet;Marta Dabek;Danièle Daviaud

  • Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota

    Matteo Serino;Elodie Luche;Sandra Grès;Audrey Baylac

  • Apelin Stimulates Glucose Utilization in Normal and Obese Insulin-Resistant Mice

    Cédric Dray;Cédric Dray;Claude Knauf;Claude Knauf;Danièle Daviaud;Danièle Daviaud;Aurélie Waget;Aurélie Waget

  • Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer.

    Ludivine Bochet;Camille Lehuede;Stephanie Dauvillier;Yuan Yuan Wang

  • Altered Gut Microbiota and Endocannabinoid System Tone in Obese and Diabetic Leptin-Resistant Mice: Impact on Apelin Regulation in Adipose Tissue

    Lucie Geurts;Vladimir Lazarevic;Muriel Derrien;Amandine Everard

  • Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells

    Yuan Yuan Wang;Yuan Yuan Wang;Camille Attané;Delphine Milhas;Béatrice Dirat

  • TNFα up-regulates apelin expression in human and mouse adipose tissue

    Danièle Daviaud;Jérémie Boucher;Stéphane Gesta;Cédric Dray

  • Apelin, diabetes, and obesity.

    Isabelle Castan-Laurell;Cédric Dray;Camille Attané;Thibaut Duparc

  • The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease.

    Lucile Garidou;Lucile Garidou;Céline Pomié;Céline Pomié;Pascale Klopp;Pascale Klopp;Aurélie Waget;Aurélie Waget

  • LPA1 Receptor Activation Promotes Renal Interstitial Fibrosis

    Jean-Philippe Pradère;Julie Klein;Sandra Grès;Charlotte Guigné

  • Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer.

    Ikrame Lazar;Emily Clement;Stéphanie Dauvillier;Delphine Milhas

  • Effect of endurance training on skeletal muscle myokine expression in obese men: identification of apelin as a novel myokine.

    Besse-Patin A;Montastier E;Vinel C;Castan-Laurell I

  • The exerkine apelin reverses age-associated sarcopenia

    Claire Vinel;Laura Lukjanenko;Aurelie Batut;Simon Deleruyelle

  • Loss of ATM positively regulates the expression of hypoxia inducible factor 1 (HIF-1) through oxidative stress: Role in the physiopathology of the disease.

    Marielle Ousset;Fanny Bouquet;Frédérique Fallone;Denis Biard

  • Lysophosphatidic acid synthesis and release.

    Céline Pagès;Marie-Françoise Simon;Philippe Valet;Jean Sébastien Saulnier-Blache

  • Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity

    Victor Laurent;Victor Laurent;Adrien Guérard;Adrien Guérard;Catherine Mazerolles;Sophie Le Gonidec;Sophie Le Gonidec

  • SHP2 sails from physiology to pathology.

    Mylène Tajan;Audrey de Rocca Serra;Philippe Valet;Thomas Edouard

  • Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer.

    Yuan-Yuan Wang;Camille Lehuédé;Camille Lehuédé;Camille Lehuédé;Victor Laurent;Victor Laurent;Béatrice Dirat;Béatrice Dirat;Béatrice Dirat

  • Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice

    Camille Attané;Camille Foussal;Sophie Le Gonidec;Alexandre Benani

Frequent Co-Authors

Jean-Louis Montastruc
Jean-Louis Montastruc Grenoble Alpes University
Patrice D. Cani
Patrice D. Cani Université Catholique de Louvain
Angelo Parini
Angelo Parini Inserm : Institut national de la santé et de la recherche médicale
Luc Pénicaud
Luc Pénicaud Federal University of Toulouse Midi-Pyrénées
Pierre Monsan
Pierre Monsan Institut National des Sciences Appliquées de Toulouse
Sandrine Andrieu
Sandrine Andrieu Federal University of Toulouse Midi-Pyrénées

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