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Mary-Ellen Harper

Mary-Ellen Harper

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
23259
World Ranking
4298
National Ranking
144

Overview

Mary-Ellen Harper is affiliated with the University of Ottawa in Canada. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a total of 100 and 66 publications respectively. Within these fields, they focus on subdisciplines such as Molecular Biology, Physiology, Immunology, Genetics, and Clinical Biochemistry.

The scientist's work addresses several main topics, notably:

  • Mitochondrial Function and Pathology
  • Adipose Tissue and Metabolism
  • Diet and metabolism studies
  • ATP Synthase and ATPases Research
  • Metabolism and Genetic Disorders
  • Muscle metabolism and nutrition
  • Metabolomics and Mass Spectrometry Studies

Mary-Ellen Harper has contributed scholarly articles to various academic venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory), 9 publications
  • American Journal of Physiology-Endocrinology and Metabolism, 4 publications
  • Nature Metabolism, 3 publications
  • Obesity Reviews, 2 publications
  • Redox Biology, 2 publications

Their recent notable papers include the following:

  • Role of Glutathione in Cancer: From Mechanisms to Therapies, 2020, Biomolecules
  • GDF15 promotes weight loss by enhancing energy expenditure in muscle, 2023, Nature
  • MCL-1Matrix maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions, 2020, Cell Death and Disease
  • Factors affecting weight loss variability in obesity, 2020, Metabolism
  • The TNFα/TNFR2 axis mediates natural killer cell proliferation by promoting aerobic glycolysis, 2023, Cellular and Molecular Immunology

Collaboration is a significant element in their research output. Frequent co-authors include:

  • Chantal A. Pileggi
  • Miroslava Čuperlović-Culf
  • David A. Patten
  • Ruth McPherson
  • Robert Dent

Best Publications

  • Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

    Sven Enerbäck;Anders Jacobsson;Elizabeth M. Simpson;Carmen Guerra

  • Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism.

    Armand Valsesia;Qiao-Ping Wang;Qiao-Ping Wang;Nele Gheldof;Jerome Carayol

  • Targeted disruption of the beta 3-adrenergic receptor gene.

    Vedrana S. Susulic;Robert C. Frederich;Joel Lawitts;Effie Tozzo

  • Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

    Mireille Khacho;Alysen Clark;Devon S. Svoboda;Joelle Azzi

  • Uncoupling proteins and the control of mitochondrial reactive oxygen species production.

    Ryan J. Mailloux;Mary-Ellen Harper

  • Role of Glutathione in Cancer: From Mechanisms to Therapies

    Luke Kennedy;Jagdeep K. Sandhu;Jagdeep K. Sandhu;Mary-Ellen Harper;Miroslava Cuperlovic-Culf;Miroslava Cuperlovic-Culf

  • SirT1 regulates energy metabolism and response to caloric restriction in mice.

    Gino Boily;Erin L. Seifert;Lisa Bevilacqua;Xiao Hong He

  • Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1

    Kyoko Tsukiyama-Kohara;Francis Poulin;Michinori Kohara;Christine T. DeMaria

  • Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3.

    Da-Wei Gong;Shadi Monemdjou;Oksana Gavrilova;Lisa R. Leon

  • Loss of the Parkinson’s Disease-linked gene DJ-1 perturbs mitochondrial dynamics

    I. Irrcher;H. Aleyasin;E.L. Seifert;S.J. Hewitt

  • Physiological role of UCP3 may be export of fatty acids from mitochondria when fatty acid oxidation predominates: an hypothesis.

    Jean Himms-Hagen;Mary-Ellen Harper

  • OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand.

    David A Patten;Jacob Wong;Mireille Khacho;Vincent Soubannier

  • Beta3-adrenergic receptors on white and brown adipocytes mediate beta3-selective agonist-induced effects on energy expenditure, insulin secretion, and food intake. A study using transgenic and gene knockout mice.

    Danica Grujic;Vedrana S. Susulic;Mary-Ellen Harper;Jean Himms-Hagen

  • Invited Review: Uncoupling proteins and thermoregulation

    George Argyropoulos;Mary-Ellen Harper

  • MicroRNA-133 Controls Brown Adipose Determination in Skeletal Muscle Satellite Cells by Targeting Prdm16

    Hang Yin;Alessandra Pasut;Vahab D. Soleimani;C. Florian Bentzinger

  • Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics

    Ryan J. Mailloux;Skye L. McBride;Mary-Ellen Harper

  • Ageing, oxidative stress, and mitochondrial uncoupling

    M. E. Harper;L. Bevilacqua;Kevork Hagopian;R. Weindruch

  • Galactose Enhances Oxidative Metabolism and Reveals Mitochondrial Dysfunction in Human Primary Muscle Cells

    Céline Aguer;Daniela Gambarotta;Ryan J. Mailloux;Cynthia Moffat

  • Electron Transport Chain-dependent and -independent Mechanisms of Mitochondrial H2O2 Emission during Long-chain Fatty Acid Oxidation

    Erin L. Seifert;Carmen Estey;Jian Y. Xuan;Mary-Ellen E. Harper

  • Restriction of energy intake, energy expenditure, and aging

    Jon J Ramsey;Mary Ellen Harper;Richard Weindruch;Richard Weindruch

Frequent Co-Authors

Ruth McPherson
Ruth McPherson University of Ottawa
Oliver Fiehn
Oliver Fiehn University of California, Davis
Richard Weindruch
Richard Weindruch University of Wisconsin–Madison
Martin D. Brand
Martin D. Brand Buck Institute for Research on Aging
Ruth S. Slack
Ruth S. Slack University of Ottawa
W. Timothy Garvey
W. Timothy Garvey University of Alabama at Birmingham
David S. Park
David S. Park New York University
William L. Stanford
William L. Stanford Ottawa Hospital
Gary R. Hunter
Gary R. Hunter University of Alabama at Birmingham
Wim H. M. Saris
Wim H. M. Saris Maastricht University

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