Mary-Ellen Harper mainly focuses on Mitochondrion, Internal medicine, Endocrinology, Cell biology and Uncoupling protein. His Mitochondrion research includes themes of Oxidative stress, Reactive oxygen species, Oxidative phosphorylation and ATP synthase. His research on Internal medicine frequently links to adjacent areas such as Cellular differentiation.
As a part of the same scientific family, Mary-Ellen Harper mostly works in the field of Endocrinology, focusing on Adenosine triphosphate and, on occasion, Metabolism, Macrophage and Cholesterol. The various areas that Mary-Ellen Harper examines in his Cell biology study include Transcription factor and Ectopic expression. Mary-Ellen Harper interconnects Basal metabolic rate, Thermogenesis and Fatty acid metabolism in the investigation of issues within Uncoupling protein.
His primary areas of investigation include Internal medicine, Endocrinology, Mitochondrion, Biochemistry and Cell biology. His study in Weight loss, Thermogenesis, Fatty acid metabolism, Thermogenin and Metabolism is carried out as part of his studies in Internal medicine. His Skeletal muscle, Insulin resistance, Adipose tissue, Insulin and Brown adipose tissue investigations are all subjects of Endocrinology research.
His Mitochondrion study combines topics in areas such as Oxidative stress, Oxidative phosphorylation, Glutathione and Reactive oxygen species. The Oxidative phosphorylation study combines topics in areas such as Cardiac muscle, Biophysics, Adenosine triphosphate and Hormone, Euthyroid. The concepts of his Cell biology study are interwoven with issues in mitochondrial fusion, Cell type and Programmed cell death.
The scientist’s investigation covers issues in Cell biology, Mitochondrion, Internal medicine, Endocrinology and Oxidative phosphorylation. Mary-Ellen Harper has included themes like Glycolysis, Glycogen and Lysine in his Cell biology study. The various areas that he examines in his Mitochondrion study include Glutathione, Glutaredoxin 2, Acetylation and Skeletal muscle.
His work in Internal medicine addresses subjects such as Cardiology, which are connected to disciplines such as Diabetes mellitus. His research integrates issues of Fatty acid and Fatty liver in his study of Endocrinology. His Oxidative phosphorylation study incorporates themes from Oxidative stress, Embryonic stem cell, Cardiac muscle, Conditional gene knockout and Alternative splicing.
His primary scientific interests are in Mitochondrion, Cell biology, Internal medicine, Blood proteins and Obesity. His biological study spans a wide range of topics, including Respiratory function, Beta oxidation, Fibrillation and Acetylation. His Cell biology research incorporates themes from SIRT3, Sirtuin, Brown adipose tissue and Thermogenesis.
His research investigates the connection between Internal medicine and topics such as Endocrinology that intersect with issues in Metabolomics. His research investigates the connection between Obesity and topics such as Body mass index that intersect with problems in Weight loss, Genetic association and Genome-wide association study. He has researched Oxidative stress in several fields, including Reactive oxygen species and Oxidative phosphorylation.
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Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese
Sven Enerbäck;Anders Jacobsson;Elizabeth M. Simpson;Carmen Guerra.
Nature (1997)
Targeted disruption of the beta 3-adrenergic receptor gene.
Vedrana S. Susulic;Robert C. Frederich;Joel Lawitts;Effie Tozzo.
Journal of Biological Chemistry (1995)
SirT1 regulates energy metabolism and response to caloric restriction in mice.
Gino Boily;Erin L. Seifert;Lisa Bevilacqua;Xiao Hong He.
PLOS ONE (2008)
Uncoupling proteins and the control of mitochondrial reactive oxygen species production.
Ryan J. Mailloux;Mary-Ellen Harper.
Free Radical Biology and Medicine (2011)
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1
Kyoko Tsukiyama-Kohara;Francis Poulin;Michinori Kohara;Christine T. DeMaria.
Nature Medicine (2001)
Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3.
Da-Wei Gong;Shadi Monemdjou;Oksana Gavrilova;Lisa R. Leon.
Journal of Biological Chemistry (2000)
Loss of the Parkinson’s Disease-linked gene DJ-1 perturbs mitochondrial dynamics
I. Irrcher;H. Aleyasin;E.L. Seifert;S.J. Hewitt.
Human Molecular Genetics (2010)
Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program
Mireille Khacho;Alysen Clark;Devon S. Svoboda;Joelle Azzi.
Cell Stem Cell (2016)
Physiological role of UCP3 may be export of fatty acids from mitochondria when fatty acid oxidation predominates: an hypothesis.
Jean Himms-Hagen;Mary-Ellen Harper.
Experimental Biology and Medicine (2001)
Invited Review: Uncoupling proteins and thermoregulation
George Argyropoulos;Mary-Ellen Harper.
Journal of Applied Physiology (2002)
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