World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
18151
World Ranking
4861
National Ranking
63

Overview

Gustavo Barja is affiliated with the Complutense University of Madrid in Spain. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine.

Their work covers several subfields including Molecular Biology, Aging, Physiology, Endocrine and Autonomic Systems, and Aquatic Science.

Key research topics explored by Barja include:

  • Mitochondrial Function and Pathology
  • Genetics, Aging, and Longevity in Model Organisms
  • Adipose Tissue and Metabolism
  • Metabolomics and Mass Spectrometry Studies
  • Circadian rhythm and melatonin
  • DNA Repair Mechanisms
  • Redox biology and oxidative stress

Frequent publication venues for Barja include:

  • Experimental Gerontology
  • GeroScience
  • Aging
  • Redox Biology
  • FEBS Journal

Their recent scholarly output includes the following papers:

  • Mitochondrial ROS production, oxidative stress and aging within and between species: Evidences and recent advances on this aging effector, 2023, Experimental Gerontology
  • Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian longevity, 2020, Redox Biology
  • Is the NDUFV2 subunit of the hydrophilic complex I domain a key determinant of animal longevity?, 2021, FEBS Journal
  • Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals, 2020, GeroScience
  • Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity, 2020, GeroScience

Barja has collaborated frequently with several coauthors, including:

  • Reinald Pamplona
  • Mariona Jové
  • Natàlia Mota-Martorell
  • José Gómez
  • Alba Naudí

Best Publications

  • Free radicals and aging

    Gustavo Barja

  • Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals

    Gustavo Barja;Asunción Herrero

  • Mitochondrial oxygen radical generation and leak: sites of production in states 4 and 3, organ specificity, and relation to aging and longevity.

    Gustavo Barja

  • The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach

    R Perez-Campo;M López-Torres;S Cadenas;C Rojas

  • Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart

    Ricardo Gredilla;Alberto Sanz;Monica Lopez-Torres;Gustavo Barja

  • International conference on the healthy effect of virgin olive oil.

    Francisco Perez-Jimenez;G. Alvarez De Cienfuegos;Lina Badimon;G. Barja

  • Membrane Fatty Acid Unsaturation, Protection against Oxidative Stress, and Maximum Life Span

    Reinald Pamplona;Gustavo Barja;Manuel Portero-Otín

  • Updating the Mitochondrial Free Radical Theory of Aging: An Integrated View, Key Aspects, and Confounding Concepts

    Gustavo Barja

  • Low Mitochondrial Free Radical Production Per Unit O2 Consumption Can Explain the Simultaneous Presence of High Longevity and High Aerobic Metabolic Rate in Birds

    G Barja;S Cadenas;C Rojas;R Pérez-Campo

  • Is the Mitochondrial Free Radical Theory of Aging Intact

    Alberto Sanz;Reinald Pamplona;Gustavo Barja

  • Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria

    Mónica López-Torres;Ricardo Gredilla;Alberto Sanz;Gustavo Barja

  • Effects of aging and caloric restriction on mitochondrial energy production in gastrocnemius muscle and heart.

    Barry Drew;Sharon Phaneuf;Amie Dirks;Colin Selman

  • Mitochondrial Free Radical Production and Aging in Mammals and Birdsa

    Gustavo Barja

  • Aging in vertebrates, and the effect of caloric restriction: a mitochondrial free radical production-DNA damage mechanism?

    Gustavo Barja

  • Mitochondrial oxidative stress, aging and caloric restriction: the protein and methionine connection.

    Reinald Pamplona;Gustavo Barja

  • Rate of generation of oxidative stress-related damage and animal longevity.

    Gustavo Barja

  • Endogenous oxidative stress: relationship to aging, longevity and caloric restriction.

    Gustavo Barja

  • Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon.

    A Herrero;G Barja

  • Localization at complex I and mechanism of the higher free radical production of brain nonsynaptic mitochondria in the short-lived rat than in the longevous pigeon.

    Barja G;Herrero A

  • Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins

    Alberto Sanz;Pilar Caro;Victoria Ayala;Manuel Portero-Otin

Frequent Co-Authors

Reinald Pamplona
Reinald Pamplona University of Lleida
Manuel Portero-Otin
Manuel Portero-Otin University of Lleida
Christiaan Leeuwenburgh
Christiaan Leeuwenburgh University of Florida
Vincenzo Solfrizzi
Vincenzo Solfrizzi University of Bari Aldo Moro
Suzanne R. Thorpe
Suzanne R. Thorpe University of South Carolina
Maurizio Battino
Maurizio Battino Marche Polytechnic University
José L. Quiles
José L. Quiles University of Granada
Colin Selman
Colin Selman University of Glasgow
Lina Badimon
Lina Badimon Hospital de la Santa Creu i Sant Pau
Penny M. Kris-Etherton
Penny M. Kris-Etherton Pennsylvania State University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Gustavo Barja

Trending Scientists