World's Best Scientists 2026 revealed!
Manuel Portero-Otin

Manuel Portero-Otin

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
17450
World Ranking
4641
National Ranking
56

Overview

Manuel Portero-Otin is affiliated with the University of Lleida in Spain and has a research focus primarily spanning medicine and biochemistry, genetics, and molecular biology. Their work intersects multiple subfields such as molecular biology, physiology, neurology, biological psychiatry, and clinical biochemistry.

The scientist's research topics emphasize several key areas, including:

  • Amyotrophic Lateral Sclerosis Research
  • Metabolomics and Mass Spectrometry Studies
  • Mitochondrial Function and Pathology
  • Diet and Metabolism Studies
  • Gut Microbiota and Health
  • Adipose Tissue and Metabolism
  • Tryptophan and Brain Disorders

Portero-Otin's publication record includes papers in various respected journals. Some notable recent papers are:

  • "Microbiota alterations in proline metabolism impact depression," published in 2022 in Cell Metabolism
  • "Obesity Impairs Short-Term and Working Memory through Gut Microbial Metabolism of Aromatic Amino Acids," published in 2020 in Cell Metabolism
  • "Dietary AGEs as Exogenous Boosters of Inflammation," published in 2021 in Nutrients
  • "Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile," published in 2020 in Microbiome
  • "Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression," published in 2021 in Brain Communications

The frequent co-authors collaborating with Portero-Otin include:

  • Reinald Pamplona
  • Mariona Jové
  • Joaquím Sol
  • Isidró Ferrer
  • Pascual Torres

Their publications commonly appear in the following venues:

  • Scientific Reports
  • Nutrients
  • Redox Biology
  • Antioxidants
  • Cell Metabolism

Best Publications

  • A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling

    Karim S. Echtay;Telma C. Esteves;Julian L. Pakay;Mika B. Jekabsons

  • Pathological aspects of lipid peroxidation

    Anne Negre-Salvayre;Nathalie Auge;Victoria Ayala;Huveyda Basaga

  • Hyperglycemia and glycation in diabetic complications.

    Anne Negre-Salvayre;Robert Salvayre;Nathalie Augé;Reinald Pamplona

  • Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis.

    Ekaterina V. Ilieva;Victòria Ayala;Mariona Jové;Esther Dalfó

  • Dietary Advanced Glycation End Products and Their Role in Health and Disease

    Jaime Uribarri;María Dolores del Castillo;María Pía de la Maza;Rosana Filip

  • Membrane Fatty Acid Unsaturation, Protection against Oxidative Stress, and Maximum Life Span

    Reinald Pamplona;Gustavo Barja;Manuel Portero-Otín

  • Proteins in Human Brain Cortex Are Modified by Oxidation, Glycoxidation, and Lipoxidation: EFFECTS OF ALZHEIMER DISEASE AND IDENTIFICATION OF LIPOXIDATION TARGETS *

    Reinald Pamplona;Esther Dalfó;Victòria Ayala;Maria Josep Bellmunt

  • Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

    Asimina Hiona;Alberto Sanz;Gregory C. Kujoth;Reinald Pamplona

  • Evidence of oxidative stress in the neocortex in incidental Lewy body disease.

    Esther Dalfó;Manuel Portero-Otín;Victoria Ayala;Anna Martínez

  • Obesity changes the human gut mycobiome.

    M. Mar Rodríguez;Daniel Pérez;Felipe Javier Chaves;Eduardo Esteve

  • Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins

    Alberto Sanz;Pilar Caro;Victoria Ayala;Manuel Portero-Otin

  • Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals.

    Reinald Pamplona;Manuel Portero-Otín;David Riba;Cristina Ruiz

  • Stimulation of suicidal erythrocyte death by methylglyoxal.

    Jan P Nicolay;Juliane Schneider;Olivier M Niemoeller;Ferruh Artunc

  • Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy.

    Stéphane Fourcade;Jone López-Erauskin;Jorge Galino;Carine Duval

  • Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates.

    Anna Martínez;Manuel Portero-Otin;Reinald Pamplona;Isidre Ferrer

  • Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.

    Martin D. Brand;Reinald Pamplona;Manuel Portero-Otín;Jesús R. Requena

  • Metabolomics of human brain aging and age-related neurodegenerative diseases.

    Mariona Jové;Manuel Portero-Otín;Alba Naudí;Isidre Ferrer;Isidre Ferrer

  • Mitochondrial ATP‐Synthase in the Entorhinal Cortex Is a Target of Oxidative Stress at Stages I/II of Alzheimer's Disease Pathology

    Beatrice Terni;Jordi Boada;Manuel Portero-Otin;Reinald Pamplona

  • A low degree of fatty acid unsaturation leads to lower lipid peroxidation and lipoxidation-derived protein modification in heart mitochondria of the longevous pigeon than in the short-lived rat

    R Pamplona;M Portero-Otı́n;J.R Requena;S.R Thorpe

  • Lipidomics of human brain aging and Alzheimer's disease pathology.

    Alba Naudí;Rosanna Cabré;Mariona Jové;Victoria Ayala

Frequent Co-Authors

Reinald Pamplona
Reinald Pamplona University of Lleida
Isidro Ferrer
Isidro Ferrer University of Barcelona
Gustavo Barja
Gustavo Barja Complutense University of Madrid
Aurora Pujol
Aurora Pujol Institut d'Investigació Biomédica de Bellvitge
Wifredo Ricart
Wifredo Ricart Instituto de Salud Carlos III
José Manuel Fernández-Real
José Manuel Fernández-Real University of Girona
Rolf K. Berge
Rolf K. Berge University of Bergen
Elena Galea
Elena Galea Autonomous University of Barcelona
Francesc Villarroya
Francesc Villarroya University of Barcelona
Andrés Moya
Andrés Moya University of Valencia

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

A background in Biology or Biochemistry can open the door to several dynamic career opportunities, including roles in health information management and medical coding. Choosing the right certification is crucial—learn more about the distinctions in the certified professional coder pathway to see what’s right for you.

Salaries in this field can be competitive. If you’re interested in compensation trends and earning potential, explore detailed insights on medical coding salary.

The industry’s rapid growth offers a strong job outlook for graduates. For a balanced perspective on entering the field, understand the job outlook for medical billing and coding, including diverse roles and current demands.

Online education makes these professions more accessible than ever. If affordability is a priority, consider the affordable online him programs available today that can set you on the path toward a rewarding career in health information management.

Best Scientists Citing Manuel Portero-Otin

Trending Scientists