World's Best Scientists 2026 revealed!
Manuel Portero-Otin

Manuel Portero-Otin

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
17450
World Ranking
4640
National Ranking
56

Manuel Portero-Otin publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Manuel Portero-Otin sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 234 publications — 62nd percentile

62% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Manuel Portero-Otin D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Manuel Portero-Otin sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 78 D-Index — 77th percentile

77% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Manuel Portero-Otin is affiliated with the University of Lleida in Spain and has a research focus primarily spanning medicine and biochemistry, genetics, and molecular biology. Their work intersects multiple subfields such as molecular biology, physiology, neurology, biological psychiatry, and clinical biochemistry.

The scientist's research topics emphasize several key areas, including:

  • Amyotrophic Lateral Sclerosis Research
  • Metabolomics and Mass Spectrometry Studies
  • Mitochondrial Function and Pathology
  • Diet and Metabolism Studies
  • Gut Microbiota and Health
  • Adipose Tissue and Metabolism
  • Tryptophan and Brain Disorders

Portero-Otin's publication record includes papers in various respected journals. Some notable recent papers are:

  • "Microbiota alterations in proline metabolism impact depression," published in 2022 in Cell Metabolism
  • "Obesity Impairs Short-Term and Working Memory through Gut Microbial Metabolism of Aromatic Amino Acids," published in 2020 in Cell Metabolism
  • "Dietary AGEs as Exogenous Boosters of Inflammation," published in 2021 in Nutrients
  • "Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile," published in 2020 in Microbiome
  • "Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression," published in 2021 in Brain Communications

The frequent co-authors collaborating with Portero-Otin include:

  • Reinald Pamplona
  • Mariona Jové
  • Joaquím Sol
  • Isidró Ferrer
  • Pascual Torres

Their publications commonly appear in the following venues:

  • Scientific Reports
  • Nutrients
  • Redox Biology
  • Antioxidants
  • Cell Metabolism

Best Publications

  • A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling

    Karim S. Echtay;Telma C. Esteves;Julian L. Pakay;Mika B. Jekabsons

  • Pathological aspects of lipid peroxidation

    Anne Negre-Salvayre;Nathalie Auge;Victoria Ayala;Huveyda Basaga

  • Hyperglycemia and glycation in diabetic complications.

    Anne Negre-Salvayre;Robert Salvayre;Nathalie Augé;Reinald Pamplona

  • Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis.

    Ekaterina V. Ilieva;Victòria Ayala;Mariona Jové;Esther Dalfó

  • Dietary Advanced Glycation End Products and Their Role in Health and Disease

    Jaime Uribarri;María Dolores del Castillo;María Pía de la Maza;Rosana Filip

  • Membrane Fatty Acid Unsaturation, Protection against Oxidative Stress, and Maximum Life Span

    Reinald Pamplona;Gustavo Barja;Manuel Portero-Otín

  • Proteins in Human Brain Cortex Are Modified by Oxidation, Glycoxidation, and Lipoxidation: EFFECTS OF ALZHEIMER DISEASE AND IDENTIFICATION OF LIPOXIDATION TARGETS *

    Reinald Pamplona;Esther Dalfó;Victòria Ayala;Maria Josep Bellmunt

  • Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

    Asimina Hiona;Alberto Sanz;Gregory C. Kujoth;Reinald Pamplona

  • Evidence of oxidative stress in the neocortex in incidental Lewy body disease.

    Esther Dalfó;Manuel Portero-Otín;Victoria Ayala;Anna Martínez

  • Obesity changes the human gut mycobiome.

    M. Mar Rodríguez;Daniel Pérez;Felipe Javier Chaves;Eduardo Esteve

  • Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins

    Alberto Sanz;Pilar Caro;Victoria Ayala;Manuel Portero-Otin

  • Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals.

    Reinald Pamplona;Manuel Portero-Otín;David Riba;Cristina Ruiz

  • Stimulation of suicidal erythrocyte death by methylglyoxal.

    Jan P Nicolay;Juliane Schneider;Olivier M Niemoeller;Ferruh Artunc

  • Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy.

    Stéphane Fourcade;Jone López-Erauskin;Jorge Galino;Carine Duval

  • Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates.

    Anna Martínez;Manuel Portero-Otin;Reinald Pamplona;Isidre Ferrer

  • Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.

    Martin D. Brand;Reinald Pamplona;Manuel Portero-Otín;Jesús R. Requena

  • Metabolomics of human brain aging and age-related neurodegenerative diseases.

    Mariona Jové;Manuel Portero-Otín;Alba Naudí;Isidre Ferrer;Isidre Ferrer

  • Mitochondrial ATP‐Synthase in the Entorhinal Cortex Is a Target of Oxidative Stress at Stages I/II of Alzheimer's Disease Pathology

    Beatrice Terni;Jordi Boada;Manuel Portero-Otin;Reinald Pamplona

  • A low degree of fatty acid unsaturation leads to lower lipid peroxidation and lipoxidation-derived protein modification in heart mitochondria of the longevous pigeon than in the short-lived rat

    R Pamplona;M Portero-Otı́n;J.R Requena;S.R Thorpe

  • Lipidomics of human brain aging and Alzheimer's disease pathology.

    Alba Naudí;Rosanna Cabré;Mariona Jové;Victoria Ayala

Frequent Co-Authors

Reinald Pamplona
Reinald Pamplona University of Lleida
Isidro Ferrer
Isidro Ferrer University of Barcelona
Gustavo Barja
Gustavo Barja Complutense University of Madrid
Aurora Pujol
Aurora Pujol Institut d'Investigació Biomédica de Bellvitge
Wifredo Ricart
Wifredo Ricart Instituto de Salud Carlos III
José Manuel Fernández-Real
José Manuel Fernández-Real University of Girona
Rolf K. Berge
Rolf K. Berge University of Bergen
Elena Galea
Elena Galea Autonomous University of Barcelona
Francesc Villarroya
Francesc Villarroya University of Barcelona
Andrés Moya
Andrés Moya University of Valencia

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