Ian M. Kerr

Research.com Recognitions

• 1985 - Fellow of the Royal Society, United Kingdom

Overview

Best Publications

• How cells respond to interferons

  George R. Stark;Ian M. Kerr;Bryan R. G. Williams;Robert H. Silverman

  5258
  Citations

• Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon.

  Eliane Meurs;Karen Chong;Julien Galabru;N.Shaun B. Thomas

  1264
  Citations

• Jaks and Stats in signaling by the cytokine receptor superfamily

  James N. Ihle;Ian M. Kerr

  1184
  Citations

• A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

  Ke Shuai;George R. Stark;Ian M. Kerr;James E. Darnell

  1163
  Citations

• pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells

  Ian M. Kerr;Ronald E. Brown

  1061
  Citations

• Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

  Richard L. Friedman;Susan P. Manly;Martin McMahon;Ian M. Kerr

  871
  Citations

• Interferon-mediated protein kinase and low-molecular-weight inhibitor of protein synthesis

  Walden K. Roberts;Walden K. Roberts;Ara Hovanessian;Ronald E. Brown;Michael J. Clemens;Michael J. Clemens

  592
  Citations

• Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells

  Ara G. Hovanessian;Ronald E. Brown;Ian M. Kerr

  531
  Citations

• Complementation of a mutant cell line : central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways

  Mathias Müller;Carl Laxton;James Briscoe;Chris Schindler

  494
  Citations

• Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop.

  Jian Feng;Bruce A. Witthuhn;Tadashi Matsuda;Franz Kohlhuber

  469
  Citations

• Interferon action--sequence specificity of the ppp(A2'p)nA-dependent ribonuclease.

  Daniel H. Wreschner;Daniel H. Wreschner;John W. McCauley;John W. McCauley;John J. Skehel;Ian M. Kerr

  457
  Citations

• High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons

  Roslyn Mckendry;Joseph John;David Flavell;Mathias Müller

  377
  Citations

• A single DNA response element can confer inducibility by both alpha- and gamma-interferons.

  Laurence E. Reid;Adrian H. Brasnett;Christopher S. Gilbert;Andrew C. G. Porter

  361
  Citations

• 2-5A synthetase: assay, distribution and variation with growth or hormone status.

  George R. Stark;William J. Dower;Robert T. Schimke;Ronald E. Brown

  354
  Citations

• Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)nA) in interferon-treated cells

  D.H. Wreschner;T.C. James;R.H. Silverman;I.M. Kerr

  343
  Citations

• Interferon response element of the human gene 6-16.

  A. C. G. Porter;Y. Chernajovsky;T. C. Dale;C. S. Gilbert

  334
  Citations

• Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells

  M. Knight;M. Knight;P. J. Cayley;P. J. Cayley;Robert H Silverman;Robert H Silverman;D. H. Wreschner;D. H. Wreschner

  325
  Citations

• Purification and characterization of vaccinia virus growth factor.

  Paul Stroobant;Andrew R. Rice;William J. Gullick;Dorothy J. Cheng

  310
  Citations

• Mutational switch of an IL-6 response to an interferon-γ-like response

  Ana P. Costa-Pereira;Silvia Tininini;Birgit Strobl;Tonino Alonzi

  304
  Citations

• Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells

  B. R. G. Williams;R. R. Golgher;R. R. Golgher;R. E. Brown;C. S. Gilbert

  274
  Citations