Sandra Pellegrini

Overview

Best Publications

• Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.

  Neil Stahl;Teri G. Boulton;Thomas Farruggella;Nancy Y. Ip

  1253
  Citations

• A protein tyrosine kinase in the interferon alpha/beta signaling pathway.

  Laura Velazquez;Marc Fellous;George Stark Stark;Sandra Pellegrini

  1242
  Citations

• Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

  Claudia Lütticken;Ursula M. Wegenka;Juping Yuan;Jan Buschmann

  1031
  Citations

• The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction

  Mathias Müller;James Briscoe;Carl Laxton;Dmitry Guschin

  938
  Citations

• Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

  Xianqin Zhang;Dusan Bogunovic;Béatrice Payelle-Brogard;Véronique Francois-Newton

  589
  Citations

• A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

  D Guschin;N Rogers;J Briscoe;B Witthuhn

  567
  Citations

• Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

  S. Pellegrini;J. John;M. Shearer;I. M. Kerr

  535
  Citations

• Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

  Luis B. Barreiro;Luis B. Barreiro;Meriem Ben-Ali;Hélène Quach;Guillaume Laval

  460
  Citations

• The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs).

  Sandra Pellegrini;Isabelle Dusanter‐Fourt

  398
  Citations

• Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways†

  Yuhei Nishimura;Christa L. Martin;Araceli Vazquez-Lopez;Sarah J. Spence

  343
  Citations

• The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha.

  Suiyang Li;S. Labrecque;M. C. Gauzzi;A. R. Cuddihy

  329
  Citations

• The receptor of the type I interferon family.

  G. Uzé;G. Schreiber;J. Piehler;S. Pellegrini

  326
  Citations

• The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

  Josiane Ragimbeau;Elisabetta Dondi;Andrés Alcover;Pierre Eid

  298
  Citations

• Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome.

  Marije E.C. Meuwissen;Rachel Schot;Sofija Buta;Grétel Oudesluijs

  273
  Citations

• Early events in signalling by interferons

  Sandra Pellegrini;Chris Schindler

  259
  Citations

• Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase.

  M C Gauzzi;L Velazquez;R McKendry;K E Mogensen

  255
  Citations

• Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli.

  Darragh Duffy;Darragh Duffy;Vincent Rouilly;Valentina Libri;Milena Hasan

  254
  Citations

• USP18-Based Negative Feedback Control Is Induced by Type I and Type III Interferons and Specifically Inactivates Interferon α Response

  Véronique François-Newton;Gabriel Magno de Freitas Almeida;Béatrice Payelle-Brogard;Danièle Monneron

  252
  Citations

• Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.

  Laura Velazquez;Knud E. Mogensen;Giovanna Barbieri;Marc Fellous

  210
  Citations

• Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons.

  Joseph John;Roslyn Mckendry;Sandra Pellegrini;David Flavell

  208
  Citations