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Neuroscience

D-Index
42
Citations
11928
World Ranking
7520
National Ranking
3241

Overview

Bennett G. Novitch is affiliated with the University of California, Los Angeles in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience, with a specific focus on subfields such as Molecular Biology, Developmental Neuroscience, Genetics, Cancer Research, and Cellular and Molecular Neuroscience.

Their work covers a variety of main research topics, including:

  • Neurogenesis and neuroplasticity mechanisms
  • MicroRNA in disease regulation
  • Single-cell and spatial transcriptomics
  • Pluripotent Stem Cells Research
  • Muscle Physiology and Disorders
  • Tissue Engineering and Regenerative Medicine
  • Epigenetics and DNA Methylation

Novitch has contributed to recent research publications, with papers appearing in multiple reputable venues. Notable recent papers include:

  • Identification of neural oscillations and epileptiform changes in human brain organoids, 2021, Nature Neuroscience
  • Fibroblasts in heart scar tissue directly regulate cardiac excitability and arrhythmogenesis, 2023, Science
  • Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates, 2020, Cell Reports
  • Rigor and reproducibility in human brain organoid research: Where we are and where we need to go, 2024, Stem Cell Reports
  • TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids, 2022, Stem Cell Reports

Frequently, Novitch has published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, and Stem Cell Reports. Other venues include Zenodo (CERN European Organization for Nuclear Research) and Nature Neuroscience.

Co-authorship has been a strong component of Novitch's research activities. Frequent collaborators include:

  • Ranmal A. Samarasinghe
  • Jessie E. Buth
  • István Módy
  • Momoko Watanabe
  • Kathrin Plath

Their academic output demonstrates an interdisciplinary approach connecting molecular biology techniques to neuroscience questions, particularly in stem cell research, neural development, and organoid modeling. Novitch's work contributes data valuable for understanding cellular mechanisms underlying brain development, regenerative medicine, and disease modeling across various biological contexts.

Best Publications

  • Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD

    Orna Halevy;Bennett G. Novitch;Douglas B. Spicer;Stephen X. Skapek

  • Vertebrate neurogenesis is counteracted by Sox1–3 activity

    Magdalena Bylund;Elisabeth Andersson;Bennett G Novitch;Jonas Muhr

  • Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2.

    Bennett G. Novitch;Albert I. Chen;Thomas M. Jessell

  • Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism

    Eric Dessaud;Lin Lin Yang;Lin Lin Yang;Katy Hill;Barny Cox

  • Directed differentiation of human-induced pluripotent stem cells generates active motor neurons.

    Saravanan Karumbayaram;Bennett G. Novitch;Michaela Patterson;Joy A. Umbach

  • Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal.

    Andrew B. Lassar;Stephen X. Skapek;Bennett Novitch

  • Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

    William R. Sellers;Bennett G. Novitch;Satoshi Miyake;Agnieszka Heith

  • A requirement for retinoic acid-mediated transcriptional activation in ventral neural patterning and motor neuron specification

    Bennett G. Novitch;Hynek Wichterle;Thomas M. Jessell;Shanthini Sockanathan;Shanthini Sockanathan

  • Sox9 and NFIA Coordinate a Transcriptional Regulatory Cascade during the Initiation of Gliogenesis

    Peng Kang;Hyun Kyoung Lee;Stacey M. Glasgow;Meggie Finley

  • Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection

    Momoko Watanabe;Jessie E. Buth;Neda Vishlaghi;Luis de la Torre-Ubieta

  • Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle.

    B G Novitch;G J Mulligan;T Jacks;A B Lassar

  • 25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model

    Chunfeng Li;Yong-Qiang Deng;Shuo Wang;Feng Ma;Feng Ma

  • Olig2 directs astrocyte and oligodendrocyte formation in postnatal subventricular zone cells.

    Christine A. G. Marshall;Bennett G. Novitch;James E. Goldman

  • Identification of neural oscillations and epileptiform changes in human brain organoids.

    Ranmal A Samarasinghe;Osvaldo A Miranda;Jessie E Buth;Simon Mitchell;Simon Mitchell

  • Coordinated Actions of the Forkhead Protein Foxp1 and Hox Proteins in the Columnar Organization of Spinal Motor Neurons

    David L. Rousso;Zachary B. Gaber;Zachary B. Gaber;Deneen Wellik;Edward E. Morrisey

  • Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.

    Pawel Niewiadomski;Jennifer H. Kong;Robert Ahrends;Robert Ahrends;Yan Ma

  • pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation.

    Bennett G. Novitch;Douglas B. Spicer;Paul S. Kim;Wang L. Cheung

  • Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog.

    Eric Dessaud;Vanessa Ribes;Nikolaos Balaskas;Lin Lin Yang

  • Foxp-Mediated Suppression of N-Cadherin Regulates Neuroepithelial Character and Progenitor Maintenance in the CNS

    David L. Rousso;Caroline Alayne Pearson;Zachary B. Gaber;Amaya Miquelajauregui

  • Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord

    Supraja G. Varadarajan;Jennifer H. Kong;Keith D. Phan;Tzu Jen Kao

  • Coordinated Actions of the Forkhead Protein Foxp1 and Hox Proteins in the Columnar Organization of Spinal Motor Neurons (DOI: 10.1016/j.neuron.2008.06.025)

    David L. Rousso;Zachary B. Gaber;Deneen Wellik;Edward E. Morrisey

Frequent Co-Authors

Daniel H. Geschwind
Daniel H. Geschwind University of California, Los Angeles
Peyman Golshani
Peyman Golshani University of California, Los Angeles
Thomas M. Jessell
Thomas M. Jessell Columbia University
Istvan Mody
Istvan Mody University of California, Los Angeles
Jack M. Parent
Jack M. Parent University of Michigan–Ann Arbor
Hynek Wichterle
Hynek Wichterle Columbia University
Ren Sun
Ren Sun University of California, Los Angeles
Brett H. Graham
Brett H. Graham Baylor College of Medicine
Yong-Qiang Deng
Yong-Qiang Deng Academy of Military Medical Sciences
Shuo Wang
Shuo Wang Nankai University

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