World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
163
Citations
105383
World Ranking
97
National Ranking
63

Research.com Recognitions

  • 2016 - Ralph W. Gerard Prize in Neuroscience, Society for Neuroscience
  • 2014 - Gruber Prize in Neuroscience, Society for Neuroscience
  • 2012 - Canada Gairdner International Award
  • 2009 - Perl-UNC Prize, University of North Carolina at Chapel Hill Defining Molecular Mechanisms that Regulate the Development of Neural Circuits
  • 2008 - Kavli Prize, The Kavli Foundation for discoveries on the developmental and functional logic of neuronal circuits
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2003 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 2002 - Member of the National Academy of Sciences
  • 2001 - Member of the National Academy of Medicine (NAM)

Overview

Thomas M. Jessell was affiliated with Columbia University in the United States. Their research focused extensively on neuroscience and biochemistry, genetics, and molecular biology, contributing to various subfields such as cell biology, cellular and molecular neuroscience, molecular biology, neurology, and cognitive neuroscience.

Their recent published papers include:

  • Differential Loss of Spinal Interneurons in a Mouse Model of ALS, 2020, Neuroscience
  • Genetic targeting of adult Renshaw cells using a Calbindin 1 destabilized Cre allele for intersection with Parvalbumin or Engrailed1, 2021, Scientific Reports
  • Distinct anatomical and functional corticospinal inputs innervate different spinal neuron types, 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • Muscle-derived Cues are Required to Specify Proprioceptor Pool Identity, 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • Potentiation of active locomotor state by spinal-projecting serotonergic neurons, 2024, bioRxiv (Cold Spring Harbor Laboratory)

Their frequent co-authors were:

  • Susan Brenner-Morton
  • Jay B. Bikoff
  • Alina Salamatina
  • Jerry H. Yang
  • Linjing Fang

Their work was commonly published in several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuroscience
  • Scientific Reports
  • UNC Libraries

The main topics covered in their research were:

  • Zebrafish Biomedical Research Applications
  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Nerve injury and regeneration
  • Neurogenesis and neuroplasticity mechanisms
  • Neuroendocrine regulation and behavior
  • Transcranial Magnetic Stimulation Studies

Over the course of their career, Thomas M. Jessell received several awards, including:

  • Ralph W. Gerard Prize in Neuroscience, Society for Neuroscience, 2016
  • Gruber Prize in Neuroscience, Society for Neuroscience, 2014
  • Canada Gairdner International Award, 2012
  • Perl-UNC Prize, University of North Carolina at Chapel Hill, 2009, for defining molecular mechanisms that regulate the development of neural circuits
  • Kavli Prize, The Kavli Foundation, 2008, for discoveries on the developmental and functional logic of neuronal circuits
  • Fellow of the American Association for the Advancement of Science (AAAS), 2006
  • Robert J. and Claire Pasarow Foundation Medical Research Award, 2003
  • Member of the National Academy of Sciences, 2002
  • Member of the National Academy of Medicine (NAM), 2001

Best Publications

  • Principles of Neural Science

    Eric R. Kandel;James H. Schwartz;Thomas M. Jessell

  • Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

    Shankar Srinivas;Tomoko Watanabe;Chyuan-Sheng Lin;Chris M William

  • Neuronal specification in the spinal cord: inductive signals and transcriptional codes

    Thomas M. Jessell

  • Directed Differentiation of Embryonic Stem Cells into Motor Neurons

    Hynek Wichterle;Ivo Lieberam;Jeffery A. Porter;Thomas M. Jessell

  • The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

    Tito Serafini;Timothy E. Kennedy;Michael J. Gaiko;Christine Mirzayan

  • A homeodomain protein code specifying progenitor cell identity and neuronal fate in the ventral neural tube

    Thomas M. Jessell;James Briscoe;Johan Ericson;Johan Ericson

  • Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes

    T. Tsuchida;M. Ensini;S.B. Morton;M. Baldassare

  • Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

    Makiko Nagai;Diane B Re;Tetsuya Nagata;Alcmène Chalazonitis

  • Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

    Karel F Liem;Gabi Tremml;Henk Roelink;Thomas M Jessell

  • Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling

    J Ericson;P Rashbass;A Schedl;S Brenner-Morton

  • Simultaneous Denoising, Deconvolution, and Demixing of Calcium Imaging Data

    Eftychios A. Pnevmatikakis;Daniel Soudry;Yuanjun Gao;Timothy A. Machado

  • Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

    H Roelink;J.A Porter;C Chiang;Y Tanabe

  • Two Critical Periods of Sonic Hedgehog Signaling Required for the Specification of Motor Neuron Identity

    Johan Ericson;Susan Morton;Atsushi Kawakami;Henk Roelink

  • Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

    H. Roelink;A. Augsburger;J. Heemskerk;V. Korzh

  • Diversity and Pattern in the Developing Spinal Cord

    Yasuto Tanabe;Thomas M. Jessell

  • Axon guidance and the patterning of neuronal projections in vertebrates

    Jane Dodd;Thomas M. Jessell

  • Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo

    T. L. Yaksh;T. M. Jessell;R. Gamse;A. W. Mudge

  • Opiate analgesics inhibit substance P release from rat trigeminal nucleus

    Unknown

  • Molecular characterization of a functional cDNA encoding the serotonin 1c receptor.

    David Julius;Amy B. MacDermott;Richard Axel;Thomas M. Jessell

  • Requirement for LIM Homeobox Gene Isl1 in Motor Neuron Generation Reveals a Motor Neuron– Dependent Step in Interneuron Differentiation

    Samuel L. Pfaff;Monica Mendelsohn;Colin L. Stewart;Thomas Edlund

  • Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

    J. Briscoe;L. Sussel;P. Serup;D. Hartigan-O'Connor

  • Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons

    J. Dodd;S.B. Morton;D. Karagogeos;M. Yamamoto

  • Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

    Ulf Ahlgren;Samuel L. Pfaff;Samuel L. Pfaff;Thomas M. Jessell;Thomas Edlund

Frequent Co-Authors

Silvia Arber
Silvia Arber University of Basel
Eric R. Kandel
Eric R. Kandel Columbia University
Yutaka Yoshida
Yutaka Yoshida Cornell University
Marc Tessier-Lavigne
Marc Tessier-Lavigne Xaira Therapeutics
Samuel L. Pfaff
Samuel L. Pfaff Salk Institute for Biological Studies
James H. Schwartz
James H. Schwartz Columbia University
John L.R. Rubenstein
John L.R. Rubenstein University of California, San Francisco
Robert M. Brownstone
Robert M. Brownstone University College London
Hynek Wichterle
Hynek Wichterle Columbia University
David Julius
David Julius University of California, San Francisco

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Best Scientists Citing Thomas M. Jessell