World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
92
Citations
92296
World Ranking
1002
National Ranking
532

Research.com Recognitions

  • 2020 - Kavli Prize, The Kavli Foundation for their transformative discovery of receptors for temperature and pressure.
  • 2020 - BBVA Foundation Frontiers of Knowledge Award
  • 2020 - Breakthrough Prize in Life Sciences for discovering molecules, cells, and mechanisms underlying pain sensation.
  • 2017 - Canada Gairdner International Award
  • 2013 - Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson for his discovery of the molecular mechanism that controls thermosensation.
  • 2012 - Member of the National Academy of Medicine (NAM)
  • 2007 - W. Alden Spencer Award, College of Physicians and Surgeons
  • 2005 - Fellow of the American Academy of Arts and Sciences
  • 2004 - Member of the National Academy of Sciences
  • 2000 - Perl-UNC Prize, University of North Carolina at Chapel Hill For Cloning the Capsaicin Receptor.

Overview

David Julius is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Neuroscience and Medicine, with a focus on several subfields of study including Sensory Systems, Physiology, Cellular and Molecular Neuroscience, Complementary and Alternative Medicine, and Nutrition and Dietetics.

The scientist's work addresses key topics such as Ion Channels and Receptors, Herbal Medicine Research Studies, Gastrointestinal Motility and Disorders, Biochemical Analysis and Sensing Techniques, Pain Mechanisms and Treatments, Ion Channel Regulation and Function, and Neurobiology and Insect Physiology Research.

David Julius has published extensively in various scientific venues. Frequent publication outlets include bioRxiv (Cold Spring Harbor Laboratory), IUPHAR/BPS Guide to Pharmacology CITE, Nature, Cell, and the Annual Review of Biochemistry.

Some recent notable papers authored or co-authored by David Julius include:

  • Structural snapshots of TRPV1 reveal mechanism of polymodal functionality, 2021, Cell
  • Irritant-evoked activation and calcium modulation of the TRPA1 receptor, 2020, Nature
  • Gut enterochromaffin cells drive visceral pain and anxiety, 2023, Nature
  • Sensory TRP Channels in Three Dimensions, 2022, Annual Review of Biochemistry
  • TRPV1 drugs alter core body temperature via central projections of primary afferent sensory neurons, 2022, eLife

They have collaborated frequently with several researchers, including:

  • Yifan Cheng
  • Kouki K Touhara
  • Stuart M. Brierley
  • Nathaniel T. Blair
  • Ingrid Carvacho

David Julius has received multiple awards and honors over the years, such as:

  • BBVA Foundation Frontiers of Knowledge Award (2020)
  • Kavli Prize, The Kavli Foundation (2020) for their transformative discovery of receptors for temperature and pressure
  • Breakthrough Prize in Life Sciences (2020) for discovering molecules, cells, and mechanisms underlying pain sensation
  • Canada Gairdner International Award (2017)
  • Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson (2013) for the discovery of the molecular mechanism that controls thermosensation
  • Member of the National Academy of Medicine (NAM) (2012)
  • W. Alden Spencer Award, College of Physicians and Surgeons (2007)
  • Fellow of the American Academy of Arts and Sciences (2005)
  • Member of the National Academy of Sciences (2004)
  • Perl-UNC Prize, University of North Carolina at Chapel Hill (2000) for cloning the Capsaicin Receptor

Best Publications

  • The capsaicin receptor: a heat-activated ion channel in the pain pathway

    Michael J. Caterina;Mark A. Schumacher;Makoto Tominaga;Tobias A. Rosen

  • Cellular and Molecular Mechanisms of Pain

    Allan I. Basbaum;Diana M. Bautista;Grégory Scherrer;David Julius

  • Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

    M. J. Caterina;A. Leffler;A. B. Malmberg;W. J. Martin

  • Identification of a cold receptor reveals a general role for TRP channels in thermosensation

    David D. McKemy;Werner M. Neuhausser;David Julius

  • Molecular mechanisms of nociception

    David Julius;Allan I. Basbaum

  • The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

    Makoto Tominaga;Michael J Caterina;Annika B Malmberg;Tobias A Rosen

  • Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

    Peter M. Zygmunt;Jesper Petersson;David A. Andersson;Huai Hu Chuang

  • The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway

    Michael J Caterina;David Julius

  • A capsaicin-receptor homologue with a high threshold for noxious heat.

    Michael J. Caterina;Tobias A. Rosen;Makoto Tominaga;Anthony J. Brake

  • Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

    Sven-Eric Jordt;Diana M. Bautista;Huai-hu Chuang;David D. McKemy

  • TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.

    Diana M. Bautista;Sven Eric Jordt;Tetsuro Nikai;Pamela R. Tsuruda

  • Structure of the TRPV1 ion channel determined by electron cryo-microscopy

    Maofu Liao;Erhu Cao;David Julius;Yifan Cheng

  • Identification of the platelet ADP receptor targeted by antithrombotic drugs.

    Gunther Hollopeter;Hans-Michael Jantzen;Diana Vincent;Georgia Li

  • The P2Y12 receptor regulates microglial activation by extracellular nucleotides

    Sharon E Haynes;Gunther Hollopeter;Gunther Hollopeter;Guang Yang;Dana Kurpius

  • Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors

    Laurence H. Tecott;Linda M. Sun;Susan F. Akana;Alison M. Strack

  • The menthol receptor TRPM8 is the principal detector of environmental cold

    Diana M. Bautista;Jan Siemens;Joshua M. Glazer;Pamela R. Tsuruda

  • Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition.

    Huai-hu Chuang;Elizabeth D. Prescott;Haeyoung Kong;Shannon Shields

  • TRPA1 mediates formalin-induced pain

    Colleen R. McNamara;Josh Mandel-Brehm;Diana M. Bautista;Jan Siemens

  • Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

    Andres V. Maricq;Andrew S. Peterson;Anthony J. Brake;Richard M. Myers

  • TRP Channels and Pain

    David Julius

  • New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor

    Anthony J. Brake;Michael J. Wagenbach;David Julius

  • TRPV1 structures in distinct conformations reveal activation mechanisms

    Erhu Cao;Maofu Liao;Yifan Cheng;David Julius

Frequent Co-Authors

Allan I. Basbaum
Allan I. Basbaum University of California, San Francisco
Laurence H. Tecott
Laurence H. Tecott University of California, San Francisco
Thomas M. Jessell
Thomas M. Jessell Columbia University
Stuart M. Brierley
Stuart M. Brierley Flinders University
Cheryl L. Stucky
Cheryl L. Stucky Medical College of Wisconsin
Uta Francke
Uta Francke Stanford University
Nicholas T. Ingolia
Nicholas T. Ingolia University of California, Berkeley
Amy B. MacDermott
Amy B. MacDermott Columbia University
William J. Martin
William J. Martin National Institutes of Health
Roger A. Nicoll
Roger A. Nicoll University of California, San Francisco

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