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Genetics

D-Index
75
Citations
34367
World Ranking
1868
National Ranking
235

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Nicholas M. Luscombe is affiliated with the Okinawa Institute of Science and Technology in Japan. Their research focuses primarily on Biochemistry, Genetics, and Molecular Biology, with particular expertise in Molecular Biology, Ecology, and Genetics. The scope of their work extends into related subfields such as Global and Planetary Change and Oceanography.

The main topics addressed in Luscombe's research include RNA Research and Splicing, RNA and protein synthesis mechanisms, and RNA modifications and cancer. Additional areas of interest encompass Genomics and Phylogenetic Studies, Protist diversity and phylogeny, Genomics and Chromatin Dynamics, as well as Marine Ecology and Invasive Species.

Frequent co-authors collaborating with Luscombe are:

  • Jernej Ule
  • Charles Plessy
  • Yongkai Tan
  • Aki Masunaga
  • Anob M. Chakrabarti

The preferred publication venues for Luscombe's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • F1000Research
  • Nature Communications
  • Wellcome Open Research
  • Genome biology

Notable recent papers authored or co-authored by Luscombe are:

  • "Pervasive chromosomal instability and karyotype order in tumour evolution," 2020, Nature
  • "RNA modifications detection by comparative Nanopore direct RNA sequencing," 2021, Nature Communications
  • "What is AI? Applications of artificial intelligence to dermatology," 2020, British Journal of Dermatology
  • "TDP-43 condensation properties specify its RNA-binding and regulatory repertoire," 2021, Cell
  • "RADICL-seq identifies general and cell type-specific principles of genome-wide RNA-chromatin interactions," 2020, Nature Communications

Luscombe has been recognized as a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • An integrated encyclopedia of DNA elements in the human genome

    Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins

  • A census of human transcription factors: function, expression and evolution

    Juan M. Vaquerizas;Sarah K. Kummerfeld;Sarah K. Kummerfeld;Sarah A. Teichmann;Nicholas M. Luscombe;Nicholas M. Luscombe

  • A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

    Richard M. Myers;John Stamatoyannopoulos;Michael Snyder;Ian Dunham

  • DNA-Binding Specificities of Human Transcription Factors

    Arttu Jolma;Jian Yan;Thomas Whitington;Jarkko Toivonen

  • iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

    Julian König;Kathi Zarnack;Gregor Rot;Tomaž Curk

  • Genomic analysis of regulatory network dynamics reveals large topological changes

    Nicholas M. Luscombe;M. Madan Babu;Haiyuan Yu;Michael Snyder

  • Amino acid–base interactions: a three-dimensional analysis of protein–DNA interactions at an atomic level

    Nicholas M. Luscombe;Roman A. Laskowski;Janet M. Thornton

  • Structure and evolution of transcriptional regulatory networks.

    M Madan Babu;Nicholas M Luscombe;L Aravind;Mark Gerstein

  • Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

    Borbala Mifsud;Filipe Tavares-Cadete;Alice N Young;Robert Sugar

  • An overview of the structures of protein-DNA complexes

    Nicholas M Luscombe;Susan E Austin;Helen M Berman;Janet M Thornton;Janet M Thornton

  • What is Bioinformatics? A Proposed Definition and Overview of the Field

    N. M. Luscombe;D. Greenbaum;M. Gerstein

  • Annotation Transfer Between Genomes: Protein–Protein Interologs and Protein–DNA Regulogs

    Haiyuan Yu;Nicholas M. Luscombe;Hao Xin Lu;Xiaowei Zhu

  • Protein clefts in molecular recognition and function.

    R. A. Laskowski;N. M. Luscombe;M. B. Swindells;J. M. Thornton

  • Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

    Samra Turajlic;Samra Turajlic;Hang Xu;Kevin Litchfield;Andrew Rowan

  • Protein-RNA interactions: a structural analysis.

    Susan Jones;David T. A. Daley;Nicholas M. Luscombe;Helen M. Berman

  • Protein–RNA interactions: new genomic technologies and perspectives

    Julian König;Kathi Zarnack;Nicholas M. Luscombe;Nicholas M. Luscombe;Jernej Ule

  • Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities

    Arttu Jolma;Teemu Kivioja;Jarkko Toivonen;Lu Cheng

  • The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements

    Stefan Schoenfelder;Mayra Furlan-Magaril;Borbala Mifsud;Filipe Tavares-Cadete;Filipe Tavares-Cadete

  • Direct Competition between hnRNP C and U2AF65 Protects the Transcriptome from the Exonization of Alu Elements

    Kathi Zarnack;Julian König;Mojca Tajnik;Mojca Tajnik;Iñigo Martincorena

  • Erratum: Protein–RNA interactions: new genomic technologies and perspectives

    Julian König;Kathi Zarnack;Nicholas M. Luscombe;Jernej Ule

Frequent Co-Authors

Jernej Ule
Jernej Ule The Francis Crick Institute
Mark Gerstein
Mark Gerstein Yale University
Juan M. Vaquerizas
Juan M. Vaquerizas Max Planck Society
Paul Bertone
Paul Bertone University of Cambridge
Michael Snyder
Michael Snyder Stanford University
Janet M. Thornton
Janet M. Thornton European Bioinformatics Institute
Asifa Akhtar
Asifa Akhtar Max Planck Society
Fiona M. Watt
Fiona M. Watt King's College London
Boris Lenhard
Boris Lenhard Imperial College London
Jiang Qian
Jiang Qian Johns Hopkins University School of Medicine

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