D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 66 Citations 28,070 166 World Ranking 1802 National Ranking 69

Research.com Recognitions

Awards & Achievements

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Gene expression

Nicholas M. Luscombe spends much of his time researching Genetics, Transcription factor, Computational biology, Gene and Regulation of gene expression. Genome, Human genome, Chromatin, Protein family and Promoter are among the areas of Genetics where Nicholas M. Luscombe concentrates his study. In Genome, he works on issues like Conserved sequence, which are connected to Function, Molecular evolution and Genomic organization.

His studies deal with areas such as Transcription, Systematic evolution of ligands by exponential enrichment and Gene regulatory network as well as Transcription factor. Nicholas M. Luscombe interconnects RNA, Small nucleolar RNA, BAP1 and Functional genomics in the investigation of issues within Computational biology. The various areas that Nicholas M. Luscombe examines in his Regulation of gene expression study include Enhancer and Gene expression.

His most cited work include:

  • An integrated encyclopedia of DNA elements in the human genome (2642 citations)
  • A User's Guide to the Encyclopedia of DNA Elements (ENCODE) (1178 citations)
  • A census of human transcription factors: function, expression and evolution (1096 citations)

What are the main themes of his work throughout his whole career to date?

Nicholas M. Luscombe focuses on Computational biology, Genetics, Genome, Gene and Cell biology. His work carried out in the field of Computational biology brings together such families of science as Gene expression, RNA, Yeast, Chromatin and DNA sequencing. His Chromatin study which covers Transcription that intersects with RNA polymerase II.

His research in Genome is mostly concerned with Human genome. His Gene research integrates issues from Cell and Embryo. Nicholas M. Luscombe has included themes like Transcriptome, Cell fate determination, RNA-binding protein and Intron in his Cell biology study.

He most often published in these fields:

  • Computational biology (66.20%)
  • Genetics (51.41%)
  • Genome (64.08%)

What were the highlights of his more recent work (between 2018-2021)?

  • Computational biology (66.20%)
  • Genome (64.08%)
  • Chromatin (47.18%)

In recent papers he was focusing on the following fields of study:

His main research concerns Computational biology, Genome, Chromatin, Cell biology and RNA. His study in Computational biology is interdisciplinary in nature, drawing from both Transcriptome, Yeast, Gene, DNA repair and Genome editing. His Genome study incorporates themes from Evolutionary biology and Nucleosome.

Nucleosome is the subject of his research, which falls under Genetics. In his study, Gene expression and ENCODE is inextricably linked to Transcription, which falls within the broad field of Chromatin. His Cell biology research is multidisciplinary, incorporating perspectives in Translation, RNA-binding protein and Intron.

Between 2018 and 2021, his most popular works were:

  • Target-Specific Precision of CRISPR-Mediated Genome Editing. (88 citations)
  • Target-Specific Precision of CRISPR-Mediated Genome Editing. (88 citations)
  • Target-Specific Precision of CRISPR-Mediated Genome Editing. (88 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Gene expression

His scientific interests lie mostly in Computational biology, Chromatin, Genome, Transcription and RNA. His study in Computational biology is interdisciplinary in nature, drawing from both Transcriptome, Gene, splice, Small nuclear ribonucleoprotein and ICLIP. His Chromatin study combines topics in areas such as Genome editing, DNA repair and Cell biology.

His Genome study combines topics from a wide range of disciplines, such as Chromatin remodeling and CRISPR. The various areas that Nicholas M. Luscombe examines in his RNA study include ENCODE and Nanopore sequencing. Nicholas M. Luscombe interconnects Regulation of gene expression, Nuclear localization sequence and DNA in the investigation of issues within ENCODE.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

An integrated encyclopedia of DNA elements in the human genome

Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins.
PMC (2012)

2767 Citations

A census of human transcription factors: function, expression and evolution

Juan M. Vaquerizas;Sarah K. Kummerfeld;Sarah K. Kummerfeld;Sarah A. Teichmann;Nicholas M. Luscombe;Nicholas M. Luscombe.
Nature Reviews Genetics (2009)

1685 Citations

A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

Richard M. Myers;John Stamatoyannopoulos;Michael Snyder;Ian Dunham.
PLOS Biology (2011)

1331 Citations

Genomic analysis of regulatory network dynamics reveals large topological changes

Nicholas M. Luscombe;M. Madan Babu;Haiyuan Yu;Michael Snyder.
Nature (2004)

1164 Citations

DNA-Binding Specificities of Human Transcription Factors

Arttu Jolma;Jian Yan;Thomas Whitington;Jarkko Toivonen.
Cell (2013)

1147 Citations

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

Julian König;Kathi Zarnack;Gregor Rot;Tomaž Curk.
Nature Structural & Molecular Biology (2010)

1059 Citations

Amino acid–base interactions: a three-dimensional analysis of protein–DNA interactions at an atomic level

Nicholas M. Luscombe;Roman A. Laskowski;Janet M. Thornton.
Nucleic Acids Research (2001)

1056 Citations

Structure and evolution of transcriptional regulatory networks.

M Madan Babu;Nicholas M Luscombe;L Aravind;Mark Gerstein.
Current Opinion in Structural Biology (2004)

1004 Citations

Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

Borbala Mifsud;Filipe Tavares-Cadete;Alice N Young;Robert Sugar.
Nature Genetics (2015)

866 Citations

An overview of the structures of protein-DNA complexes

Nicholas M Luscombe;Susan E Austin;Helen M Berman;Janet M Thornton;Janet M Thornton.
Genome Biology (2000)

800 Citations

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