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D-Index & Metrics

Molecular Biology

D-Index
77
Citations
27238
World Ranking
1099
National Ranking
87

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jernej Ule is affiliated with The Francis Crick Institute in the United Kingdom. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with an emphasis on Molecular Biology. Other subfields include Cancer Research, Neurology, Genetics, and Cellular and Molecular Neuroscience.

The scientist's work covers several main topics, including:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Cancer-related molecular mechanisms research
  • Amyotrophic Lateral Sclerosis Research
  • RNA regulation and disease
  • Genomics and Chromatin Dynamics

Jernej Ule has a substantial publication record, with frequent contributions to venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature
  • SSRN Electronic Journal
  • Molecular Cell

Recent notable papers include:

  • TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A, 2022, Nature
  • RNA modifications detection by comparative Nanopore direct RNA sequencing, 2021, Nature Communications
  • CLIP and complementary methods, 2021, Nature Reviews Methods Primers
  • TDP-43 condensation properties specify its RNA-binding and regulatory repertoire, 2021, Cell
  • Cytotoxic T-cells mediate exercise-induced reductions in tumor growth, 2020, eLife

Frequent co-authors collaborating with Jernej Ule include Nicholas M. Luscombe, Anob M. Chakrabarti, Oscar G. Wilkins, Flora Lee, and Charlotte Capitanchik.

Among their recognitions, Jernej Ule is a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • HITS-CLIP yields genome-wide insights into brain alternative RNA processing

    Donny D. Licatalosi;Aldo Mele;John J. Fak;Jernej Ule

  • CLIP identifies Nova-regulated RNA networks in the brain.

    Jernej Ule;Kirk B. Jensen;Kirk B. Jensen;Matteo Ruggiu;Matteo Ruggiu;Aldo Mele;Aldo Mele

  • iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

    Julian König;Kathi Zarnack;Gregor Rot;Tomaž Curk

  • Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

    James Robert Tollervey;Tomaž Curk;Boris Rogelj;Michael Briese

  • CLIP: a method for identifying protein-RNA interaction sites in living cells.

    Jernej Ule;Kirk Jensen;Aldo Mele;Robert B. Darnell

  • An RNA map predicting Nova-dependent splicing regulation

    Jernej Ule;Giovanni Stefani;Giovanni Stefani;Aldo Mele;Matteo Ruggiu

  • TDP-43 regulates its mRNA levels through a negative feedback loop

    Youhna M Ayala;Laura De Conti;S Eréndira Avendaño-Vázquez;Ashish Dhir

  • Aberrant methylation of tRNAs links cellular stress to neuro‐developmental disorders

    Sandra Blanco;Sabine Dietmann;Joana V Flores;Shobbir Hussain

  • Nova regulates brain-specific splicing to shape the synapse

    Jernej Ule;Aljaž Ule;Joanna Spencer;Alan Williams

  • Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution

    Jernej Ule;Jernej Ule;Benjamin J. Blencowe

  • The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

    Dalibor Blazek;Jiri Kohoutek;Koen Bartholomeeusen;Eric Johansen

  • Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic.

    Youn Bok Lee;Han Jou Chen;João N. Peres;Jorge Gomez-Deza

  • Protein–RNA interactions: new genomic technologies and perspectives

    Julian König;Kathi Zarnack;Nicholas M. Luscombe;Nicholas M. Luscombe;Jernej Ule

  • NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

    Shobbir Hussain;Abdulrahim A. Sajini;Sandra Blanco;Sabine Dietmann

  • Direct Competition between hnRNP C and U2AF65 Protects the Transcriptome from the Exonization of Alu Elements

    Kathi Zarnack;Julian König;Mojca Tajnik;Mojca Tajnik;Iñigo Martincorena

  • iCLIP: Protein–RNA interactions at nucleotide resolution

    Ina Huppertz;Jan Attig;Andrea D’Ambrogio;Laura E. Easton

  • Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing

    Madapura M. Pradeepa;Heidi G. Sutherland;Jernej Ule;Graeme R. Grimes

  • Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging.

    Lilach Soreq;Lilach Soreq;Jamie Rose;Eyal Soreq;John Hardy

  • Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43

    Peter J Lukavsky;Dalia Daujotyte;Dalia Daujotyte;James R Tollervey;James R Tollervey;Jernej Ule;Jernej Ule

  • Erratum: Protein–RNA interactions: new genomic technologies and perspectives

    Julian König;Kathi Zarnack;Nicholas M. Luscombe;Jernej Ule

Frequent Co-Authors

Nicholas M. Luscombe
Nicholas M. Luscombe The Francis Crick Institute
Robert B. Darnell
Robert B. Darnell Rockefeller University
Christopher W.J. Smith
Christopher W.J. Smith University of Cambridge
Randall S. Johnson
Randall S. Johnson University of Cambridge
Mina Ryten
Mina Ryten University College London
John L. Rinn
John L. Rinn University of Colorado Boulder
Ashok R. Venkitaraman
Ashok R. Venkitaraman Agency for Science, Technology and Research
Tyson A. Clark
Tyson A. Clark Pacific Biosciences (United States)
Andreas E. Kulozik
Andreas E. Kulozik Heidelberg University
Christopher Shaw
Christopher Shaw King's College London

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