What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Molecular biology, Cell biology, Messenger RNA, Gene expression and Programmed cell death.
His research in Molecular biology focuses on subjects like Oligonucleotide, which are connected to Flow cytometry, Intracellular and Cell membrane.
His Cell biology study integrates concerns from other disciplines, such as Secretion, Transcription factor and Transcription.
His research integrates issues of IκBα, Nucleus and Cytosol in his study of Transcription.
His Messenger RNA research includes themes of RNA and Transfection.
In the field of Gene expression, his study on Reporter gene overlaps with subjects such as Dephosphorylation and Negative feedback.
His most cited work include:
- Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression (993 citations)
- Pulsatile Stimulation Determines Timing and Specificity of NF-κB-Dependent Transcription (438 citations)
- Encoded microcarriers for high-throughput multiplexed detection. (310 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Cell biology, Molecular biology, Biochemistry, Internal medicine and Transcription.
His studies in Cell biology integrate themes in fields like Tumor necrosis factor alpha, Cell, Transcription factor and Gene expression.
His biological study spans a wide range of topics, including NF-κB and Cytokine.
The various areas that David G. Spiller examines in his Gene expression study include Regulation of gene expression and Paracrine signalling.
His Molecular biology study incorporates themes from Cell culture, RNA, Messenger RNA, Oligonucleotide and Mitochondrion.
Biochemistry and Biophysics are commonly linked in his work.
He most often published in these fields:
- Cell biology (34.59%)
- Molecular biology (25.95%)
- Biochemistry (12.43%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (34.59%)
- Transcription (10.27%)
- Molecular biology (25.95%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cell biology, Transcription, Molecular biology, Transcription factor and Cell.
His research in Cell biology is mostly concerned with Signal transduction.
His Transcription study combines topics in areas such as Luciferase and Prolactin.
His Molecular biology research is multidisciplinary, relying on both Glycerol-3-phosphate dehydrogenase, NAD+ kinase, Biochemistry and Nucleotide, Nudix hydrolase.
His work on Cell cycle as part of general Cell research is frequently linked to Population, thereby connecting diverse disciplines of science.
David G. Spiller focuses mostly in the field of Gene expression, narrowing it down to topics relating to Regulation of gene expression and, in certain cases, NFKB1.
Between 2013 and 2021, his most popular works were:
- Inflammasome-dependent IL-1β release depends upon membrane permeabilisation. (121 citations)
- Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states (51 citations)
- Tight Control of Hypoxia-inducible Factor-α Transient Dynamics Is Essential for Cell Survival in Hypoxia (41 citations)
In his most recent research, the most cited papers focused on:
David G. Spiller mostly deals with Cell biology, Signal transduction, Regulation of gene expression, Genetics and Live cell imaging.
His research in Cell biology intersects with topics in Cell growth, NFKB1, HEK 293 cells, Cell cycle and Programmed cell death.
As a member of one scientific family, David G. Spiller mostly works in the field of Signal transduction, focusing on Tumor necrosis factor alpha and, on occasion, Cytokine.
The various areas that David G. Spiller examines in his Regulation of gene expression study include Cell, Gene expression and Transcription.
His studies deal with areas such as Phenotype, Reporter gene and Gene expression profiling as well as Transcription.
He works mostly in the field of Apoptosis, limiting it down to topics relating to Melanoma and, in certain cases, Molecular biology, as a part of the same area of interest.
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