David G. Spiller

Overview

Best Publications

• Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression

  D. E. Nelson;A. E. C. Ihekwaba;M. Elliott;J. R. Johnson

  1528
  Citations

• Pulsatile Stimulation Determines Timing and Specificity of NF-κB-Dependent Transcription

  Louise Ashall;Caroline A. Horton;David E. Nelson;Pawel Paszek

  657
  Citations

• Measurement of single-cell dynamics.

  David G. Spiller;Christopher D. Wood;David A. Rand;Michael R. H. White

  467
  Citations

• Encoded microcarriers for high-throughput multiplexed detection.

  Robert Wilson;Andrew R. Cossins;David G. Spiller

  448
  Citations

• The mitochondrial network of human neutrophils: role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis.

  Gianluca Fossati;Dale A. Moulding;David G. Spiller;Robert J. Moots

  418
  Citations

• Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.

  F Martín-Sánchez;C Diamond;C Diamond;M Zeitler;A I Gomez

  273
  Citations

• Dynamic analysis of stochastic transcription cycles

  Claire V. Harper;Bärbel Finkenstädt;Dan J. Woodcock;Sönke Friedrichsen

  264
  Citations

• Population robustness arising from cellular heterogeneity

  Pawel Paszek;Sheila Ryan;Louise Ashall;Kate Sillitoe

  222
  Citations

• Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

  Dale A. Moulding;Michael P. Blundell;David G. Spiller;Michael R.H. White

  184
  Citations

• Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells.

  Dale A. Moulding;Richard V. Giles;David G. Spiller;Michael R. H. White

  179
  Citations

• Edible mushroom (Agaricus bisporus) lectin, which reversibly inhibits epithelial cell proliferation, blocks nuclear localization sequence-dependent nuclear protein import

  Lu Gang Yu;David G. Fernig;Michael R H White;David G. Spiller

  168
  Citations

• Physiological levels of TNFα stimulation induce stochastic dynamics of NF-κB responses in single living cells

  David A Turner;Pawel Paszek;Dan J Woodcock;David E Nelson

  164
  Citations

• Antisense morpholino oligonucleotide analog induces missplicing of C-myc mRNA.

  Richard V. Giles;David G. Spiller;Richard E. Clark;David M. Tidd

  153
  Citations

• Expression of the leptin receptor in rat and human nodose ganglion neurones

  G Burdyga;D Spiller;R Morris;S Lal

  150
  Citations

• Multi-parameter analysis of the kinetics of NF-kappa B signalling and transcription in single living cells

  Glyn Nelson;Luminita Paraoan;David G. Spiller;Geraint J. C. Wilde

  148
  Citations

• In situ detection and measurement of intracellular reactive oxygen species in single isolated mature skeletal muscle fibers by real time fluorescence microscopy

  Jesus Palomero;Deborah Pye;Tabitha Kabayo;David G. Spiller

  145
  Citations

• Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo.

  Marcella Faria;David G. Spiller;Catherine Dubertret;Jeff S. Nelson

  145
  Citations

• Improving the intracellular delivery and molecular efficacy of antisense oligonucleotides in chronic myeloid leukemia cells: a comparison of streptolysin-O permeabilization, electroporation, and lipophilic conjugation.

  David G. Spiller;Richard V. Giles;John Grzybowski;David M. Tidd

  140
  Citations

• Localization of orexin-1 receptors to vagal afferent neurons in the rat and humans.

  Galina Burdyga;Simon Lal;David Spiller;Wen Jiang

  129
  Citations

• Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells

  R. V. Giles;D. G. Spiller;J. Grzybowski;R. E. Clark

  124
  Citations