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Medicine

D-Index
94
Citations
29699
World Ranking
10551
National Ranking
1012

Overview

David Back is affiliated with the University of Liverpool in the United Kingdom and specializes in medical research with a focus on infectious diseases and pharmacology. Their publication record encompasses a range of topics including drug metabolism, HIV/AIDS treatment, and clinical studies related to COVID-19.

Back has contributed to several recent papers, including:

  • "Recommendations for the Management of Drug-Drug Interactions Between the COVID-19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications," 2022, Clinical Pharmacology & Therapeutics
  • "The challenge of HIV treatment in an era of polypharmacy," 2020, Journal of the International AIDS Society
  • "Prioritization of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics," 2020, Clinical Pharmacology & Therapeutics
  • "Pharmacokinetics and Drug-Drug Interactions of Long-Acting Intramuscular Cabotegravir and Rilpivirine," 2021, Clinical Pharmacokinetics
  • "Stopping lopinavir/ritonavir in COVID-19 patients: duration of the drug interacting effect," 2020, Journal of Antimicrobial Chemotherapy

Their frequent co-authors include:

  • Catia Marzolini
  • Saye Khoo
  • Fiona Marra
  • Alison Boyle
  • Sara Gibbons

Back publishes frequently in journals such as:

  • Journal of Antimicrobial Chemotherapy
  • Clinical Pharmacology & Therapeutics
  • British Journal of Clinical Pharmacology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Cerebral Blood Flow & Metabolism

The main fields of study for Back's work are within medicine, focusing especially on subfields including:

  • Infectious Diseases
  • Pharmacology
  • Epidemiology
  • Molecular Biology
  • Computational Theory and Mathematics

The main research topics covered by Back's publications include:

  • COVID-19 Clinical Research Studies
  • Pharmacogenetics and Drug Metabolism
  • HIV/AIDS drug development and treatment
  • SARS-CoV-2 and COVID-19 Research
  • Pharmacological Receptor Mechanisms and Effects
  • Drug-Induced Hepatotoxicity and Protection
  • Pneumocystis jirovecii pneumonia detection and treatment

Best Publications

  • Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study.

    Jacques Fellay;Catia Marzolini;Emma R. Meaden;David J. Back

  • Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

    Victoria A. Eagling;John F. Tjia;David J. Back

  • Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir.

    V. A. Eagling;D. J. Back;M. G. Barry

  • Pharmacokinetics and Potential Interactions Amongst Antiretroviral Agents Used To Treat Patients with HIV Infection

    Michael Barry;Fiona Mulcahy;Concepta Merry;Sara Gibbons

  • Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations

    Michael Barry;Sara Gibbons;David Back;Fiona Mulcahy

  • St John's Wort increases expression of P-glycoprotein: Implications for drug interactions

    Martina Hennessy;D Kelleher;J P Spiers;M Barry

  • Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients.

    Concepta Merry;Michael G. Barry;Fiona Mulcahy;Kathryn L. Halifax

  • Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics.

    L M Forrester;C J Henderson;M J Glancey;D J Back

  • Predictors of Kidney Tubular Dysfunction in HIV-Infected Patients Treated with Tenofovir: A Pharmacogenetic Study

    Sonia Rodríguez-Nóvoa;Pablo Labarga;Vincent Soriano;Deirdre Egan

  • Pharmacokinetic Drug Interactions with Oral Contraceptives

    David J. Back;Michael LʼE. Orme

  • Prevalence of comedications and effect of potential drug-drug interactions in the Swiss HIV Cohort Study.

    Catia Marzolini;Luigia Elzi;Sara Gibbons;Rainer Weber

  • Principles and practice of HIV-protease inhibitor pharmacoenhancement.

    GJ Moyle;D Back

  • Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomes.

    DJ Back;JF Tjia

  • Therapeutic drug monitoring in HIV infection: current status and future directions.

    David J. Back;Giorgio Gatti;Courtney Fletcher;Rodolphe Garaffo

  • Ageing with HIV: medication use and risk for potential drug–drug interactions

    Catia Marzolini;David Back;Rainer Weber;Hansjakob Furrer

  • The interaction of phenytoin and carbamazepine with combined oral contraceptive steroids.

    P. Crawford;DJ Chadwick;C. Martin;J. Tjia

  • Darunavir: pharmacokinetics and drug interactions.

    David Back;Vanitha Sekar;Richard M W Hoetelmans

  • Clinical pharmacokinetics of oral contraceptive steroids.

    Orme Ml;Back Dj;Breckenridge Am

  • Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients

    Christoph Wyen;Heidy Hendra;Martin Vogel;Christian Hoffmann

  • Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors.

    Louise Profit;Victoria A. Eagling;David J. Back

Frequent Co-Authors

Saye Khoo
Saye Khoo University of Liverpool
Marta Boffito
Marta Boffito Imperial College London
Alan Winston
Alan Winston Imperial College London
Brian Gazzard
Brian Gazzard St Bartholomew's Hospital
Graeme Moyle
Graeme Moyle Chelsea and Westminster Hospital NHS Foundation Trust
Anton Pozniak
Anton Pozniak London School of Hygiene & Tropical Medicine
Giovanni Di Perri
Giovanni Di Perri University of Turin
Munir Pirmohamed
Munir Pirmohamed University of Liverpool
Stephen A. Ward
Stephen A. Ward Liverpool School of Tropical Medicine
David M. Burger
David M. Burger Radboud University

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