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Overview

Saye Khoo is affiliated with the University of Liverpool in the United Kingdom. Their primary research focus lies in the field of Medicine, with significant contributions to Infectious Diseases, Epidemiology, Emergency Medicine, Virology, and Pharmacology. Their work spans across several important topics including HIV/AIDS research and interventions, HIV/AIDS drug development and treatment, SARS-CoV-2 and COVID-19 research, COVID-19 clinical research studies, HIV-related health complications and treatments, HIV research and treatment, and SARS-CoV-2 detection and testing.

Throughout their career, Saye Khoo has published extensively, with notable papers including:

  • Clinical features and management of human monkeypox: a retrospective observational study in the UK (2022) - The Lancet Infectious Diseases
  • Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial (2022) - The Lancet
  • Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19 (2021) - Science Immunology
  • Recommendations for the Management of Drug-Drug Interactions Between the COVID-19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications (2022) - Clinical Pharmacology & Therapeutics
  • Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study (2020) - American Journal of Respiratory and Critical Care Medicine

Frequent collaborators in Saye Khoo's research include Laura Else, Tom Fletcher, Helen Reynolds, Malcolm G. Semple, and J. Kenneth Baillie.

The scientist's publications appear frequently in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Antimicrobial Chemotherapy
  • Clinical Infectious Diseases
  • AIDS
  • SSRN Electronic Journal

Saye Khoo's work contributes notably to several subfields of Medicine, predominantly Infectious Diseases, followed by Epidemiology, Emergency Medicine, Virology, and Pharmacology. Their research addresses critical health challenges related to viral infections such as HIV/AIDS and SARS-CoV-2, with an emphasis on clinical studies and treatment developments.

Best Publications

  • Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial.

    Sheena McCormack;David T. Dunn;Monica Desai;David I. Dolling

  • British HIV Association guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy 2008

    B G Gazzard;Jane Anderson;Abdel Babiker;Marta Boffito

  • British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2012

    Ian Williams;Duncan Churchill;Jane Anderson;Marta Boffito

  • Adenoviruses from human immunodeficiency virus-infected individuals, including two strains that represent new candidate serotypes Ad50 and Ad51 of species B1 and D, respectively.

    Jan C. De Jong;Anton G. Wermenbol;Marja W. Verweij-Uijterwaal;Kees W. Slaterus

  • Two cases of monkeypox imported to the United Kingdom, September 2018

    Aisling Vaughan;Aisling Vaughan;Emma Aarons;John Astbury;Sooria Balasegaram

  • HIV infection and stroke: current perspectives and future directions.

    Laura A Benjamin;Laura A Benjamin;Alan Bryer;Hedley C A Emsley;Saye Khoo

  • Controversies in HIV-associated neurocognitive disorders

    Sam Nightingale;Alan Winston;Scott Letendre;Benedict D Michael;Benedict D Michael

  • Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study.

    Clark D Russell;Cameron J Fairfield;Thomas M Drake;Lance Turtle

  • Predictors of Kidney Tubular Dysfunction in HIV-Infected Patients Treated with Tenofovir: A Pharmacogenetic Study

    Sonia Rodríguez-Nóvoa;Pablo Labarga;Vincent Soriano;Deirdre Egan

  • British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2012 (Updated November 2013. All changed text is cast in yellow highlight.).

    Ian Williams;Ian Williams;Duncan Churchill;Jane Anderson;Marta Boffito

  • Minimum Costs for Producing Hepatitis C Direct-Acting Antivirals for Use in Large-Scale Treatment Access Programs in Developing Countries

    Andrew Hill;Saye Khoo;Joe Fortunak;Bryony Simmons

  • Invasive aspergillosis in patients with AIDS.

    Saye H. Khoo;David W. Denning

  • Prevalence of comedications and effect of potential drug-drug interactions in the Swiss HIV Cohort Study.

    Catia Marzolini;Luigia Elzi;Sara Gibbons;Rainer Weber

  • Ageing with HIV: medication use and risk for potential drug–drug interactions

    Catia Marzolini;David Back;Rainer Weber;Hansjakob Furrer

  • Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients

    Christoph Wyen;Heidy Hendra;Martin Vogel;Christian Hoffmann

  • HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms.

    Ruben C Hartkoorn;Wai San Kwan;Victoria Shallcross;Ammara Chaikan

  • P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

    Jones K;Bray Pg;Khoo Sh;Davey Ra

  • Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro.

    P G Hoggard;S Kewn;M G Barry;S H Khoo

  • Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds.

    Laura Else;Victoria Watson;Victoria Watson;John Tjia;Andrew Hughes

  • British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2015

    Duncan Churchill;Laura Waters;Nadia Ahmed;Brian Angus

Frequent Co-Authors

David Back
David Back University of Liverpool
Marta Boffito
Marta Boffito Imperial College London
Alan Winston
Alan Winston Imperial College London
Munir Pirmohamed
Munir Pirmohamed University of Liverpool
Anton Pozniak
Anton Pozniak London School of Hygiene & Tropical Medicine
Frank A. Post
Frank A. Post King's College London
David M. Burger
David M. Burger Radboud University
Graeme Moyle
Graeme Moyle Chelsea and Westminster Hospital NHS Foundation Trust
Andrew Hill
Andrew Hill University of Liverpool
Clifford Leen
Clifford Leen Western General Hospital

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