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Izuho Hatada

Izuho Hatada

D-Index & Metrics

Molecular Biology

D-Index
49
Citations
8598
World Ranking
2635
National Ranking
198

Overview

Izuho Hatada is affiliated with Gunma University in Japan and has a research portfolio spanning biochemistry, genetics, molecular biology, and medicine. Their scientific contributions mainly focus on molecular biology, genetics, cellular and molecular neuroscience, physiology, and surgery.

Their work covers several key research topics, including:

  • CRISPR and Genetic Engineering
  • Epigenetics and DNA Methylation
  • RNA Modifications and Cancer
  • Neuroscience and Neuropharmacology Research
  • Ion Channel Regulation and Function
  • Pain Mechanisms and Treatments
  • Genetics and Neurodevelopmental Disorders

Hatada has contributed to numerous scientific papers. Some recent publications include:

  • Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity, 2020, Nature Neuroscience
  • Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome, 2020, Genome Biology
  • The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity, 2022, Nature Communications
  • Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9-SunTag Platform, 2020, International Journal of Molecular Sciences
  • Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice, 2020, Proceedings of the National Academy of Sciences

Hatada frequently collaborates with other researchers. Prominent co-authors include:

  • Takuro Horii
  • Sumiyo Morita
  • Ryosuke Kobayashi
  • Makoto Tsuda

The scientist publishes often in specialized venues, with multiple contributions appearing in the following journals:

  • Methods in Molecular Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Brain
  • International Journal of Molecular Sciences
  • Proceedings of the National Academy of Sciences

In addition to research articles, Hatada has authored books published by Springer Science+Business Media, including:

  • Epigenomics, 2022
  • Genome Editing in Animals, 2023

Best Publications

  • An imprinted gene p57KIP2 is mutated in Beckwith-Wiedemann syndrome.

    Izuho Hatada;Hirofumi Ohashi;Yoshimitsu Fukushima;Yasuhiko Kaneko

  • A genomic scanning method for higher organisms using restriction sites as landmarks.

    Izuho Hatada;Yoshihide Hayashizaki;Shinji Hirotsune;Hideyuki Komatsubara

  • Genomic imprinting of p57KIP2, a cyclin-dependent kinase inhibitor, in mouse

    Izuho Hatada;Tsunehiro Mukai

  • Structure and Engineering of Francisella novicida Cas9.

    Hisato Hirano;Jonathan S. Gootenberg;Takuro Horii;Omar O. Abudayyeh

  • Analysis of germline CDKN1C (p57KIP2) mutations in familial and sporadic Beckwith-Wiedemann syndrome (BWS) provides a novel genotype-phenotype correlation.

    Wayne W K Lam;Izuho Hatada;Sachiko Ohishi;Tsunehiro Mukai

  • Restriction landmark genomic scanning method and its various applications

    Yoshihide Hayashizaki;Shinji Hirotsune;Yasushi Okazaki;Izuho Hatada

  • Genomic Imprinting of Human p57KIP2 and Its Reduced Expression in Wilms' Tumors

    Izuho Hatada;Johji Inazawa;Tatsuo Abe;Masahiro Nakayama

  • 5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability

    Georgia Rose Kafer;Xuan Li;Takuro Horii;Isao Suetake

  • DNA methylation is linked to deacetylation of histone H3, but not H4, on the imprinted genes Snrpn and U2af1-rs1.

    Richard I. Gregory;Tamzin E. Randall;Colin A. Johnson;Sanjeev Khosla

  • miR-148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells.

    Luc Gailhouste;Laura Gomez-Santos;Keitaro Hagiwara;Izuho Hatada

  • Genome-wide profiling of promoter methylation in human

    Izuho Hatada;Masayuki Fukasawa;Mika Kimura;Sumiyo Morita

  • MeCP2-dependent repression of an imprinted miR-184 released by depolarization

    Tasuku Nomura;Mika Kimura;Takuro Horii;Sumiyo Morita

  • MiR-29 represses the activities of DNA methyltransferases and DNA demethylases

    Sumiyo Morita;Takuro Horii;Mika Kimura;Takahiro Ochiya

  • A new imprinted gene cloned by a methylation-sensitive genome scanning method

    Izuho Hatada;Takako Sugama;Tsunehiro Mukai

  • Microarray analysis of promoter methylation in lung cancers

    Masayuki Fukasawa;Masayuki Fukasawa;Mika Kimura;Mika Kimura;Sumiyo Morita;Sumiyo Morita;Kenichi Matsubara

  • Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis

    Seshiru Nakazawa;Daisuke Oikawa;Daisuke Oikawa;Ryohei Ishii;Takashi Ayaki

  • Maturation of mouse fetal germ cells in vitro

    Yayoi Obata;Tomohiro Kono;Izuho Hatada

  • New p57KIP2 mutations in Beckwith-Wiedemann syndrome

    I. Hatada;Akira Nabetani;Hiroko Morisaki;Zhenghan Xin

  • Identification of a new imprinted gene, Rian, on mouse chromosome 12 by fluorescent differential display screening.

    Izuho Hatada;Sumiyo Morita;Yayoi Obata;Yusuke Sotomaru

  • Domain regulation of imprinting cluster in Kip2/Lit1 subdomain on mouse chromosome 7F4/F5: large-scale DNA methylation analysis reveals that DMR-Lit1 is a putative imprinting control region.

    Hitomi Yatsuki;Keiichiro Joh;Ken Higashimoto;Hidenobu Soejima

Frequent Co-Authors

Tomohiro Kono
Tomohiro Kono Tokyo University of Agriculture
Hirofumi Ohashi
Hirofumi Ohashi Saitama Children's Medical Center
Takahiro Ochiya
Takahiro Ochiya Tokyo Medical University
Fuminori Tokunaga
Fuminori Tokunaga Osaka Metropolitan University
Makoto Tsuda
Makoto Tsuda Kyushu University
Yoshihiro Ogawa
Yoshihiro Ogawa Kyushu University
Yoshimitsu Fukushima
Yoshimitsu Fukushima Shinshu University
Norio Niikawa
Norio Niikawa Health Sciences University of Hokkaido
Eamonn R. Maher
Eamonn R. Maher University of Cambridge

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