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Biology and Biochemistry

D-Index
61
Citations
17917
World Ranking
11169
National Ranking
859

Overview

Farzin Farzaneh is affiliated with King's College London in the United Kingdom. Their research spans multiple fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. The primary subfields of their work include Oncology, Immunology, Molecular Biology, Genetics, and Electrical and Electronic Engineering.

The scientist's research focuses on several key topics:

  • CAR-T cell therapy research
  • Virus-based gene therapy research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • MicroRNA in disease regulation

Frequent co-authors in Farzaneh's publications include Martin Pulé, Claire Roddie, Juliana Dias, Maeve O'Reilly, and Bilyana Popova. The scientist has contributed to multiple papers published in prominent journals and venues, with some of the most cited recent publications being:

  • Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies (2020, The Lancet)
  • CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial (2021, Nature Medicine)
  • Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia (2022, Science Translational Medicine)
  • Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia (2021, Journal of Clinical Oncology)
  • Engineered Tumor-Derived Extracellular Vesicles: Potentials in Cancer Immunotherapy (2020, Frontiers in Immunology)

Publication venues where Farzaneh has frequently contributed include Blood, International Journal of Molecular Sciences, Experimental Biology and Medicine, Molecular Therapy - Methods & Clinical Development, and Cancers.

Farzaneh has also contributed to book publications, with at least one title published by Garland Science eBooks titled Functional Analysis of the Human Genome in 2020.

Best Publications

  • A Novel Duodenal Iron-Regulated Transporter, IREG1, Implicated in the Basolateral Transfer of Iron to the Circulation

    Andrew T McKie;Paola Marciani;Andreas Rolfs;Karen Brennan

  • An iron-regulated ferric reductase associated with the absorption of dietary iron

    Andrew T. McKie;Dalna Barrow;Gladys O. Latunde-Dada;Andreas Rolfs

  • Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

    Waseem Qasim;Hong Zhan;Sujith Samarasinghe;Stuart Adams

  • GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer.

    M. Mourtada-Maarabouni;M. R. Pickard;V. L. Hedge;Farzin Farzaneh

  • Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention.

    Anna Aiello;Farzin Farzaneh;Giuseppina Candore;Calogero Caruso

  • Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR.

    Sara Ghorashian;Anne Marijn Kramer;Shimobi Onuoha;Gary Wright

  • DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation.

    Farzin Farzaneh;Rosalind Zalin;Rosalind Zalin;David Brill;Sydney Shall

  • Characterization and Clinical Application of Human CD34+ Stem/Progenitor Cell Populations Mobilized into the Blood by Granulocyte Colony-Stimulating Factor

    Myrtle Y. Gordon;Nataša Levičar;Madhava Pai;Philippe Bachellier

  • Are snoRNAs and snoRNA host genes new players in cancer

    Gwyn T. Williams;Farzin Farzaneh

  • The Structure and Pharmacological Functions of Coumarins and Their Derivatives

    Longhuo Wu;Xiao Wang;William Xu;Farzin Farzaneh

  • Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies.

    Reuben Benjamin;Reuben Benjamin;Charlotte Graham;Charlotte Graham;Deborah Yallop;Agnieszka Jozwik;Agnieszka Jozwik

  • CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS)

    Shahram Y. Kordasti;Wendy Ingram;Janet Hayden;David Darling

  • CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial.

    Shaun Cordoba;Shimobi Onuoha;Simon Thomas;Daniela Soriano Pignataro

  • Growth arrest in human T-cells is controlled by the non-coding RNA growth-arrest-specific transcript 5 (GAS5).

    Mirna Mourtada-Maarabouni;Vanessa L. Hedge;Lucy Kirkham;Farzin Farzaneh

  • IL-17-producing CD4(+) T cells, pro-inflammatory cytokines and apoptosis are increased in low risk myelodysplastic syndrome.

    Shahram Y. Kordasti;Behdad Afzali;Ziyi Lim;Wendy Ingram

  • Protein transduction: an alternative to genetic intervention?

    KG Ford;BE Souberbielle;D Darling;F Farzaneh

  • Functional characterization of CD4+ T cells in aplastic anemia

    Shahram Kordasti;Shahram Kordasti;Judith Marsh;Judith Marsh;Sufyan Al-Khan;Jie Jiang;Jie Jiang

  • TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells.

    Lars Guelen;Hugh Paterson;Joop Gäken;Michelle Meyers

  • Association of ovarian malignancy with expression of platelet-derived endothelial cell growth factor.

    Karina Reynolds;Farzin Farzaneh;William P. Collins;Stuart Campbell

  • Eliciting cytotoxic T lymphocytes against acute myeloid leukemia-derived antigens: evaluation of dendritic cell-leukemia cell hybrids and other antigen-loading strategies for dendritic cell-based vaccination.

    Joanna Galea-Lauri;David Darling;Ghulam Mufti;Phillip Harrison

Frequent Co-Authors

Ghulam J. Mufti
Ghulam J. Mufti King's College London
Kypros H. Nicolaides
Kypros H. Nicolaides King's College London
Gwyn T. Williams
Gwyn T. Williams Keele University
Adrian J. Thrasher
Adrian J. Thrasher University College London
Mark G. Thomas
Mark G. Thomas University College London
Judith C. W. Marsh
Judith C. W. Marsh King's College London
Persis Amrolia
Persis Amrolia Great Ormond Street Hospital
Giovanna Lombardi
Giovanna Lombardi King's College London
Paul Veys
Paul Veys Great Ormond Street Hospital
John A. McGrath
John A. McGrath King's College London

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