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D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
18365
World Ranking
6978
National Ranking
3210

Research.com Recognitions

  • 2000 - Hellman Fellow

Overview

Chris D. Vulpe is affiliated with the University of Florida in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans a wide range of subjects, with a focus on molecular biology and hematology, complemented by work in materials chemistry, nutrition and dietetics, and health, toxicology, and mutagenesis.

The scientist's work predominantly covers topics such as CRISPR and genetic engineering, trace elements in health, iron metabolism and related disorders, advanced biosensing and bioanalysis techniques, radioactive element chemistry and processing, nanoparticles synthesis and applications, and acute myeloid leukemia research.

Chris D. Vulpe's recent scholarly articles include:

  • Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL-Specific Degrader DT2216, 2021, Molecular Cancer Therapeutics
  • The biology of mammalian multi-copper ferroxidases, 2022, BioMetals
  • Genome-scale CRISPR screens identify host factors that promote human coronavirus infection, 2022, Genome Medicine
  • Genome-wide toxicogenomic study of the lanthanides sheds light on the selective toxicity mechanisms associated with critical materials, 2021, Proceedings of the National Academy of Sciences
  • Applying genome-wide CRISPR to identify known and novel genes and pathways that modulate formaldehyde toxicity, 2020, Chemosphere

Their frequent co-authors include Abderrahmane Tagmount, Alex Loguinov, Amin Sobh, Roger M. Pallares, and Dahlia D. An.

Most of Chris D. Vulpe's publications appear in venues such as Blood, bioRxiv (Cold Spring Harbor Laboratory), Metallomics, Toxicological Sciences, and Blood Advances.

Among recognitions, Chris D. Vulpe has received the Hellman Fellow award in 2000.

Best Publications

  • Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase.

    Christopher Vulpe;Barbara Levinson;Barbara Levinson;Susan Whitney;Seymour Packman

  • Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse.

    Christopher D. Vulpe;Yien-Ming Kuo;Therese L. Murphy;Lex Cowley

  • Identification of an intestinal heme transporter.

    Majid Shayeghi;Gladys O. Latunde-Dada;Jonathan S. Oakhill;Abas H. Laftah

  • Iron-overload-related disease in HFE hereditary hemochromatosis

    Katrina J. Allen;Lyle C. Gurrin;Clare C. Constantine;Nicholas J. Osborne

  • CPx-type ATPases: a class of P-type ATPases that pump heavy metals

    Marc Solioz;Christopher Vulpe

  • Expression profiles of Arabidopsis thaliana in mineral deficiencies reveal novel transporters involved in metal homeostasis.

    Henri Wintz;Tama C. Fox;Ying-Ying Wu;Victoria Feng

  • Hepcidin expression inversely correlates with the expression of duodenal Iron transporters and Iron absorption in rats

    David M. Frazer;Sarah J. Wilkins;Erika M. Becker;Christopher D. Vulpe

  • Déjà vu in proteomics. A hit parade of repeatedly identified differentially expressed proteins

    Jiri Petrak;Robert Ivanek;Ondrej Toman;Radek Cmejla

  • Mammalian iron transport

    Gregory Jon Anderson;Christopher D. Vulpe

  • Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition.

    Louise B. Thingholm;Malte C. Rühlemann;Manja Koch;Brie Fuqua

  • Cellular Copper Transport

    Christopher D. Vulpe;Seymour Packman

  • Daphnia magna ecotoxicogenomics provides mechanistic insights into metal toxicity.

    Helen C. Poynton;Julia R. Varshavsky;Bonnie Chang;Giorgio Cavigiolio

  • Intestinal iron absorption.

    Brie K. Fuqua;Christopher D. Vulpe;Gregory J. Anderson

  • A rapid decrease in the expression of DMT1 and Dcytb but not Ireg1 or hephaestin explains the mucosal block phenomenon of iron absorption

    D M Frazer;S J Wilkins;E M Becker;T L Murphy

  • Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium.

    Tian Xia;Raymond F. Hamilton;James C. Bonner;Edward D. Crandall

  • Yeast, a model organism for iron and copper metabolism studies.

    Jeane De Freitas;Henri Wintz;J Hyoun Kim;Helen Poynton

  • Differential Gene Expression in Daphnia magna Suggests Distinct Modes of Action and Bioavailability for ZnO Nanoparticles and Zn Ions

    Helen C. Poynton;James M. Lazorchak;Christopher A. Impellitteri;Mark E. Smith

  • Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia mice.

    Huijun Chen;Zouhair K Attieh;Trent Su;Basharut A Syed

  • Cloning and gastrointestinal expression of rat hephaestin: relationship to other iron transport proteins

    David M. Frazer;Christopher D. Vulpe;Andrew T. McKie;Sarah J. Wilkins

  • Diverse mutations in patients with Menkes disease often lead to exon skipping.

    S Das;B Levinson;S Whitney;C Vulpe

Frequent Co-Authors

Gregory J. Anderson
Gregory J. Anderson QIMR Berghofer Medical Research Institute
Jane Gitschier
Jane Gitschier University of California, San Francisco
Luoping Zhang
Luoping Zhang University of California, Berkeley
Martyn T. Smith
Martyn T. Smith University of California, Berkeley
Victor R. Gordeuk
Victor R. Gordeuk University of Illinois at Chicago
Francesco Falciani
Francesco Falciani University of Liverpool
Joshua L. Dunaief
Joshua L. Dunaief University of Pennsylvania
John H. Eckfeldt
John H. Eckfeldt University of Minnesota
Joseph A. Murray
Joseph A. Murray Mayo Clinic
Aldons J. Lusis
Aldons J. Lusis University of California, Los Angeles

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