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Biology and Biochemistry

D-Index
77
Citations
25764
World Ranking
4713
National Ranking
2282

Overview

Joao A. Paulo is affiliated with Harvard University in the United States and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their research footprint spans over 500 publications, with a focus on Molecular Biology, Cell Biology, Spectroscopy, Genetics, and Epidemiology.

The scientist's main research topics include:

  • Advanced Proteomics Techniques and Applications
  • Ubiquitin and Proteasome Pathways
  • Cellular Transport and Secretion
  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Mass Spectrometry Techniques and Applications
  • RNA and Protein Synthesis Mechanisms

Joao A. Paulo has published numerous papers in leading scientific journals. Some of the recent papers include:

  • "Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I," 2020, Nature
  • "Dual proteome-scale networks reveal cell-specific remodeling of the human interactome," 2021, Cell
  • "TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples," 2020, Nature Methods
  • "A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging," 2020, Cell
  • "Full-Featured, Real-Time Database Searching Platform Enables Fast and Accurate Multiplexed Quantitative Proteomics," 2020, Journal of Proteome Research

The scientist has collaborated frequently with several co-authors, including:

  • Steven P. Gygi
  • J. Wade Harper
  • Xinyue Liu
  • Qing Yu
  • Valentina Rossio

Joao A. Paulo's publications are often found in prominent venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Proteome Research
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Nature

Best Publications

  • The BioPlex Network: A Systematic Exploration of the Human Interactome

    Edward L. Huttlin;Lily Ting;Raphael J. Bruckner;Fana Gebreab

  • Architecture of the human interactome defines protein communities and disease networks

    Edward L. Huttlin;Raphael J. Bruckner;Joao A. Paulo;Joe R. Cannon

  • Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

    Keisuke Yamamoto;Anthony Venida;Julian Yano;Douglas E. Biancur

  • The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.

    Jin-Mi Heo;Alban Ordureau;Joao A. Paulo;Jesse Rinehart

  • Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

    Edward L. Huttlin;Raphael J. Bruckner;Jose Navarrete-Perea;Joe R. Cannon

  • Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry.

    Mark P. Jedrychowski;Christiane D. Wrann;Joao A. Paulo;Kaitlyn K. Gerber

  • Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence.

    Gabriel E. Neurohr;Rachel L. Terry;Rachel L. Terry;Jette Lengefeld;Megan Bonney;Megan Bonney

  • TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples.

    Jiaming Li;Jonathan G. Van Vranken;Laura Pontano Vaites;Devin K. Schweppe

  • Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy

    Alban Ordureau;Jin-Mi Heo;David M. Duda;Joao A. Paulo

  • Streamlined Tandem Mass Tag (SL-TMT) Protocol: An Efficient Strategy for Quantitative (Phospho)proteome Profiling Using Tandem Mass Tag-Synchronous Precursor Selection-MS3

    José Navarrete-Perea;Qing Yu;Steven P. Gygi;Joao A. Paulo

  • A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

    Haopeng Xiao;Mark P. Jedrychowski;Devin K. Schweppe;Edward L. Huttlin

  • Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism

    Douglas E. Biancur;Joao A. Paulo;Beata Małachowska;Beata Małachowska;Maria Quiles Del Rey

  • Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling

    Jaeho Paek;Marian Kalocsay;Dean P. Staus;Dean P. Staus;Laura Wingler;Laura Wingler

  • TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress

    Heeseon An;Alban Ordureau;Joao A. Paulo;Christopher J. Shoemaker

  • Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics

    Devin K Schweppe;Jimmy K Eng;Qing Yu;Derek Bailey

  • Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells.

    Kenichiro Furuyama;Simona Chera;Simona Chera;Léon van Gurp;Daniel Oropeza

  • The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

    Jonathan Z. Long;Katrin J. Svensson;Leslie A. Bateman;Hua Lin

  • An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer.

    Lianfeng Wu;Ben Zhou;Noriko Oshiro-Rapley;Man Li

  • TMTpro-18plex: The Expanded and Complete Set of TMTpro Reagents for Sample Multiplexing

    Jiaming Li;Zhenying Cai;Ryan D Bomgarden;Ian Pike

  • Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

    Edward L. Huttlin;Raphael J. Bruckner;Jose Navarrete-Perea;Joe R. Cannon;Joe R. Cannon

Frequent Co-Authors

Steven P. Gygi
Steven P. Gygi Harvard University
J. Wade Harper
J. Wade Harper Harvard Medical School
Peter A. Banks
Peter A. Banks Brigham and Women's Hospital
Hanno Steen
Hanno Steen Boston Children's Hospital
Kevin M. Haigis
Kevin M. Haigis Harvard University
Daniel Finley
Daniel Finley Harvard University
Mark P. Jedrychowski
Mark P. Jedrychowski Harvard University
Alec C. Kimmelman
Alec C. Kimmelman New York University
Danesh Moazed
Danesh Moazed Harvard University
Manoj T. Duraisingh
Manoj T. Duraisingh Harvard University

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