D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 103 Citations 42,211 459 World Ranking 4314 National Ranking 2429

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

Omar Abdel-Wahab mainly investigates Cancer research, Mutation, Leukemia, Myeloid and Immunology. His Cancer research research is multidisciplinary, incorporating perspectives in Enasidenib, Haematopoiesis, Cell growth, Proto-Oncogene Proteins B-raf and Molecular biology. His Mutation study combines topics in areas such as RNA splicing, Loss function, Mutant and Function.

As part of the same scientific family, he usually focuses on Leukemia, concentrating on Myeloid leukemia and intersecting with Histone. His research integrates issues of IDH2 and IDH1 in his study of Myeloid. His Immunology research incorporates themes from Internal medicine and Erythropoiesis.

His most cited work include:

  • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. (1818 citations)
  • The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate (1401 citations)
  • Prognostic relevance of integrated genetic profiling in acute myeloid leukemia (1316 citations)

What are the main themes of his work throughout his whole career to date?

Cancer research, Internal medicine, Leukemia, Myeloid and Myeloid leukemia are his primary areas of study. His research in Cancer research intersects with topics in Haematopoiesis, Mutation, Mutant and Immunology, Bone marrow. His Haematopoiesis study deals with Molecular biology intersecting with DNA methylation.

His biological study spans a wide range of topics, including Epigenetics and RNA splicing. His Leukemia research incorporates elements of Myelodysplastic syndromes and RUNX1. His Myeloid study incorporates themes from Pathology and Somatic cell.

He most often published in these fields:

  • Cancer research (39.33%)
  • Internal medicine (21.11%)
  • Leukemia (19.78%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cancer research (39.33%)
  • RNA splicing (14.22%)
  • Cell biology (10.00%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cancer research, RNA splicing, Cell biology, Internal medicine and Cancer. Omar Abdel-Wahab is involved in the study of Cancer research that focuses on Myeloid in particular. His RNA splicing research includes elements of Carcinogenesis and Mutant.

His Cell biology study also includes fields such as

  • Proteome together with Mediator,
  • Transcription factor that intertwine with fields like Progenitor cell. His Internal medicine research includes themes of Gastroenterology and Oncology. The Haematopoiesis study combines topics in areas such as DNA damage and Somatic cell.

Between 2018 and 2021, his most popular works were:

  • Aberrant RNA Splicing in Cancer (185 citations)
  • Aberrant RNA Splicing in Cancer (185 citations)
  • Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia (79 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

His primary areas of investigation include RNA splicing, Cell biology, Cancer research, Gene and Cancer. Omar Abdel-Wahab focuses mostly in the field of RNA splicing, narrowing it down to topics relating to Exon and, in certain cases, Myeloid leukemia, Psychological repression and Mutagenesis. The study incorporates disciplines such as Chromosomal translocation, Hematology, KRAS, Histiocytosis and Leukemia in addition to Cancer research.

Leukemia is a subfield of Internal medicine that he explores. Omar Abdel-Wahab has included themes like Haematopoiesis and Stem cell in his Transcriptome study. His Haematopoiesis study also includes

  • Progenitor cell which intersects with area such as DNA methylation,
  • Genotype that connect with fields like Somatic cell and Myeloid.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.

Maria E. Figueroa;Omar Abdel-Wahab;Chao Lu;Patrick S. Ward.
Cancer Cell (2010)

2654 Citations

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

Jay P. Patel;Mithat Gönen;Maria E. Figueroa;Hugo Fernandez.
The New England Journal of Medicine (2012)

2026 Citations

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

Patrick S. Ward;Jay Patel;David R. Wise;Omar Abdel-Wahab.
Cancer Cell (2010)

1996 Citations

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Chao Lu;Patrick S. Ward;Patrick S. Ward;Gurpreet S. Kapoor;Dan Rohle;Dan Rohle.
Nature (2012)

1846 Citations

Clinical effect of point mutations in myelodysplastic syndromes.

Rafael Bejar;Kristen Stevenson;Omar Abdel-Wahab;Naomi Galili.
The New England Journal of Medicine (2011)

1683 Citations

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.

Kelly Moran-Crusio;Linsey Reavie;Alan Shih;Omar Abdel-Wahab.
Cancer Cell (2011)

1215 Citations

Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages.

Jean-François Emile;Oussama Abla;Sylvie Fraitag;Annacarin Horne.
Blood (2016)

965 Citations

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

Omar Abdel-Wahab;Ann Mullally;Cyrus Hedvat;Guillermo Garcia-Manero.
Blood (2009)

779 Citations

EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation

Wendy Béguelin;Relja Popovic;Matt Teater;Yanwen Jiang.
Cancer Cell (2013)

762 Citations

The role of mutations in epigenetic regulators in myeloid malignancies

Alan H. Shih;Omar Abdel-Wahab;Jay P. Patel;Ross L. Levine.
Nature Reviews Cancer (2012)

757 Citations

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