Member of the Association of American Physicians
Omar Abdel-Wahab mainly investigates Cancer research, Mutation, Leukemia, Myeloid and Immunology. His Cancer research research is multidisciplinary, incorporating perspectives in Enasidenib, Haematopoiesis, Cell growth, Proto-Oncogene Proteins B-raf and Molecular biology. His Mutation study combines topics in areas such as RNA splicing, Loss function, Mutant and Function.
As part of the same scientific family, he usually focuses on Leukemia, concentrating on Myeloid leukemia and intersecting with Histone. His research integrates issues of IDH2 and IDH1 in his study of Myeloid. His Immunology research incorporates themes from Internal medicine and Erythropoiesis.
Cancer research, Internal medicine, Leukemia, Myeloid and Myeloid leukemia are his primary areas of study. His research in Cancer research intersects with topics in Haematopoiesis, Mutation, Mutant and Immunology, Bone marrow. His Haematopoiesis study deals with Molecular biology intersecting with DNA methylation.
His biological study spans a wide range of topics, including Epigenetics and RNA splicing. His Leukemia research incorporates elements of Myelodysplastic syndromes and RUNX1. His Myeloid study incorporates themes from Pathology and Somatic cell.
His main research concerns Cancer research, RNA splicing, Cell biology, Internal medicine and Cancer. Omar Abdel-Wahab is involved in the study of Cancer research that focuses on Myeloid in particular. His RNA splicing research includes elements of Carcinogenesis and Mutant.
His Cell biology study also includes fields such as
His primary areas of investigation include RNA splicing, Cell biology, Cancer research, Gene and Cancer. Omar Abdel-Wahab focuses mostly in the field of RNA splicing, narrowing it down to topics relating to Exon and, in certain cases, Myeloid leukemia, Psychological repression and Mutagenesis. The study incorporates disciplines such as Chromosomal translocation, Hematology, KRAS, Histiocytosis and Leukemia in addition to Cancer research.
Leukemia is a subfield of Internal medicine that he explores. Omar Abdel-Wahab has included themes like Haematopoiesis and Stem cell in his Transcriptome study. His Haematopoiesis study also includes
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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
Maria E. Figueroa;Omar Abdel-Wahab;Chao Lu;Patrick S. Ward.
Cancer Cell (2010)
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
Jay P. Patel;Mithat Gönen;Maria E. Figueroa;Hugo Fernandez.
The New England Journal of Medicine (2012)
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
Patrick S. Ward;Jay Patel;David R. Wise;Omar Abdel-Wahab.
Cancer Cell (2010)
IDH mutation impairs histone demethylation and results in a block to cell differentiation
Chao Lu;Patrick S. Ward;Patrick S. Ward;Gurpreet S. Kapoor;Dan Rohle;Dan Rohle.
Nature (2012)
Clinical effect of point mutations in myelodysplastic syndromes.
Rafael Bejar;Kristen Stevenson;Omar Abdel-Wahab;Naomi Galili.
The New England Journal of Medicine (2011)
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Kelly Moran-Crusio;Linsey Reavie;Alan Shih;Omar Abdel-Wahab.
Cancer Cell (2011)
Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages.
Jean-François Emile;Oussama Abla;Sylvie Fraitag;Annacarin Horne.
Blood (2016)
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
Omar Abdel-Wahab;Ann Mullally;Cyrus Hedvat;Guillermo Garcia-Manero.
Blood (2009)
EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
Wendy Béguelin;Relja Popovic;Matt Teater;Yanwen Jiang.
Cancer Cell (2013)
The role of mutations in epigenetic regulators in myeloid malignancies
Alan H. Shih;Omar Abdel-Wahab;Jay P. Patel;Ross L. Levine.
Nature Reviews Cancer (2012)
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