His primary scientific interests are in Immunology, Immune system, Receptor, Cell biology and Cytokine. His work on Innate immune system, Arthritis, Proinflammatory cytokine and Lectin is typically connected to Lipoarabinomannan as part of general Immunology study, connecting several disciplines of science. The Immune system study combines topics in areas such as Activator, Phosphorylation and Bone marrow.
His Receptor study combines topics in areas such as Autoimmune encephalitis, Cancer research, Mannose and Antigen. In general Cell biology study, his work on Signal transduction and Signal transducing adaptor protein often relates to the realm of LGP2 and DEAD Box Protein 58, thereby connecting several areas of interest. His Cytokine research incorporates elements of Inflammation and Microbiology, Candida albicans.
His primary areas of study are Immunology, Microbiology, Receptor, Immune system and Arthritis. His work on Immunology deals in particular with Interleukin 17, Cytokine, Proinflammatory cytokine, Innate immune system and Rheumatoid arthritis. His Microbiology research is multidisciplinary, relying on both Host and CLEC7A.
His work carried out in the field of Receptor brings together such families of science as Lectin, Antimicrobial and Colitis. His Immune system research is multidisciplinary, incorporating perspectives in Phagocytosis, Cell biology and Bone marrow. The study incorporates disciplines such as T cell, Genetically modified mouse and Autoimmunity in addition to Arthritis.
The scientist’s investigation covers issues in Immunology, Receptor, Microbiology, Innate immune system and Cytokine. His Immunology study is mostly concerned with Interleukin 17, Arthritis, Rheumatoid arthritis, Regulatory T cell and House dust mite. His Receptor research includes themes of Lectin, Colitis, Antimicrobial, Immune system and Antigen.
Shinobu Saijo studied Immune system and Cell biology that intersect with Antigen presentation, Calcineurin and NFAT Pathway. His biological study spans a wide range of topics, including Inflammation, CLEC7A, Concanavalin A and C-type lectin. Within one scientific family, he focuses on topics pertaining to Stimulation under Cytokine, and may sometimes address concerns connected to CXCL1, TLR7, Psoriasiform Dermatitis, CXCL2 and Hemagglutinin.
Shinobu Saijo mainly focuses on Immunology, Receptor, Microbiology, Cell biology and Colitis. Shinobu Saijo conducts interdisciplinary study in the fields of Immunology and Lipoarabinomannan through his works. His Receptor research is multidisciplinary, incorporating elements of Autoimmune encephalitis, Signal transduction, Mannose and Antigen.
In general Microbiology, his work in Aspergillus fumigatus is often linked to Proteases linking many areas of study. Shinobu Saijo combines subjects such as Innate immune system, Cellular differentiation and BATF with his study of Cell biology. His studies in Colitis integrate themes in fields like Antimicrobial, Ribonuclease, Chemically-induced colitis, T reg cells and Antibody.
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Functional Specialization of Interleukin-17 Family Members
Yoichiro Iwakura;Harumichi Ishigame;Shinobu Saijo;Susumu Nakae.
Immunity (2011)
Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist–Deficient Mice
Reiko Horai;Shinobu Saijo;Hidetoshi Tanioka;Susumu Nakae.
Journal of Experimental Medicine (2000)
Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans.
Shinobu Saijo;Noriyuki Fujikado;Takahisa Furuta;Soo Hyun Chung.
Nature Immunology (2007)
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
Susumu Nakae;Shinobu Saijo;Reiko Horai;Katsuko Sudo.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans
Shinobu Saijo;Satoshi Ikeda;Keiko Yamabe;Shigeru Kakuta.
Immunity (2010)
The roles of IL-17A in inflammatory immune responses and host defense against pathogens
Yoichiro Iwakura;Susumu Nakae;Shinobu Saijo;Harumichi Ishigame.
Immunological Reviews (2008)
Loss of DExD/H Box RNA Helicase LGP2 Manifests Disparate Antiviral Responses
Thiagarajan Venkataraman;Maikel Valdes;Rachel Elsby;Shigeru Kakuta.
Journal of Immunology (2007)
STING manifests self DNA-dependent inflammatory disease
Jeonghyun Ahn;Delia Gutman;Shinobu Saijo;Glen N. Barber.
Proceedings of the National Academy of Sciences of the United States of America (2012)
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors.
Hiromitsu Hara;Chitose Ishihara;Arata Takeuchi;Takayuki Imanishi.
Nature Immunology (2007)
Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses.
Manuel Ritter;Olaf Gross;Sarah Kays;Jürgen Ruland.
Proceedings of the National Academy of Sciences of the United States of America (2010)
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