What is he best known for?
The fields of study he is best known for:
Biochemistry, Biophysics, Stereochemistry, Nuclear magnetic resonance spectroscopy and Crystallography are his primary areas of study.
The various areas that Ichio Shimada examines in his Biophysics study include Extracellular, Receptor, Intracellular, KcsA potassium channel and Protein–protein interaction.
Ichio Shimada interconnects Gating, Helix, Crystal structure, Immunoglobulin light chain and Ion channel in the investigation of issues within Stereochemistry.
His Nuclear magnetic resonance spectroscopy study combines topics in areas such as Immunoglobulin G, Molecular mass, Two-dimensional nuclear magnetic resonance spectroscopy, Analytical chemistry and Peptide.
He has researched Crystallography in several fields, including Peptide sequence, Molecule, Nuclear Overhauser effect and Binding site.
His study in Binding site is interdisciplinary in nature, drawing from both Supramolecular chemistry, Plasma protein binding and Cyclic nucleotide-binding domain.
His most cited work include:
- Three-dimensional solution structure of the B domain of staphylococcal protein A: comparisons of the solution and crystal structures. (294 citations)
- A novel NMR method for determining the interfaces of large protein-protein complexes. (250 citations)
- Differential N-glycan patterns of secreted and intracellular IgG produced in Trichoplusia ni cells. (142 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Biochemistry, Biophysics, Stereochemistry, Crystallography and Nuclear magnetic resonance spectroscopy.
His research brings together the fields of Molecular biology and Biochemistry.
His study on Biophysics also encompasses disciplines like
- Binding site which is related to area like Plasma protein binding,
- Protein structure, which have a strong connection to Membrane.
His Stereochemistry course of study focuses on Peptide and Peptide sequence.
His work on Crystal structure as part of general Crystallography research is frequently linked to Paramagnetism, bridging the gap between disciplines.
His Nuclear magnetic resonance spectroscopy research incorporates themes from Computational chemistry, Drug discovery and Analytical chemistry.
He most often published in these fields:
- Biochemistry (45.63%)
- Biophysics (37.98%)
- Stereochemistry (31.97%)
What were the highlights of his more recent work (between 2014-2021)?
- Biophysics (37.98%)
- Cell biology (13.11%)
- Protein structure (15.57%)
In recent papers he was focusing on the following fields of study:
Ichio Shimada mainly investigates Biophysics, Cell biology, Protein structure, Nuclear magnetic resonance spectroscopy and Receptor.
His research in Biophysics intersects with topics in G protein-coupled receptor, G protein and Binding site.
His work carried out in the field of Binding site brings together such families of science as Plasma protein binding and Ion channel.
The various areas that Ichio Shimada examines in his Nuclear magnetic resonance spectroscopy study include Effector, Computational chemistry and Solubility.
The Receptor study combines topics in areas such as Ligand, Cell, Signal transduction and Stereochemistry.
His Actin research is under the purview of Biochemistry.
Between 2014 and 2021, his most popular works were:
- GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures (82 citations)
- Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor (69 citations)
- Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR. (32 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Biophysics, Receptor, Protein structure, G protein-coupled receptor and Plasma protein binding.
In his papers, Ichio Shimada integrates diverse fields, such as Biophysics and Ceramide Transfer Protein.
His Receptor research incorporates elements of Macrophage, Tumor progression, Stereochemistry and Immunotherapy.
His G protein-coupled receptor research includes themes of Lipid bilayer, Ligand, Membrane protein and Drug discovery.
His Plasma protein binding study integrates concerns from other disciplines, such as Poly-binding protein, Amino acid, Gating and Binding site.
His study looks at the relationship between Binding site and topics such as Allosteric regulation, which overlap with Molecular dynamics.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
