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Hideo Takahashi

Hideo Takahashi

D-Index & Metrics

Molecular Biology

D-Index
54
Citations
8163
World Ranking
2342
National Ranking
178

Overview

Hideo Takahashi is affiliated with the University of Tokyo in Japan and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans several interconnected subfields, including immunology, clinical biochemistry, molecular biology, mechanical engineering, and mechanics of materials.

The research focus includes a range of topics primarily centered on advanced glycation end products (AGEs) and their biological impact. Additional areas of investigation cover immune response and inflammation, interferon and immune responses, S100 proteins and annexins, neutrophil, myeloperoxidase and oxidative mechanisms, mast cells and histamine, and angiogenesis with VEGF involvement in cancer.

Notable recent papers authored or co-authored by Hideo Takahashi include:

  • Osteopontin silencing attenuates bleomycin-induced murine pulmonary fibrosis by regulating epithelial-mesenchymal transition, 2021, published in Biomedicine & Pharmacotherapy
  • Histidine-Rich Glycoprotein Inhibits High-Mobility Group Box-1-Mediated Pathways in Vascular Endothelial Cells through CLEC-1A, 2020, published in iScience
  • A comparative study of sulphated polysaccharide effects on advanced glycation end-product uptake and scavenger receptor class A level in macrophages, 2020, published in Diabetes and Vascular Disease Research
  • Involvement of multiple scavenger receptors in advanced glycation end product-induced vessel tube formation in endothelial cells, 2021, published in Experimental Cell Research
  • Histamine promotes angiogenesis through a histamine H1 receptor-PKC-VEGF-mediated pathway in human endothelial cells, 2023, published in Journal of Pharmacological Sciences

Frequently, Takahashi collaborates with other researchers, with some co-authors appearing repeatedly in their body of work. These frequent collaborators include Shuji Mori, Masahiro Nishibori, Takashi Nishinaka, Ömer Faruk Hatipoğlu, and Hidenori Wake.

Their publications appear most frequently in venues such as Proceedings for Annual Meeting of The Japanese Pharmacological Society, Molecular Biology Reports, The Proceedings of Conference of Kanto Branch, The Proceedings of Mechanical Engineering Congress Japan, and Biotechnology and Applied Biochemistry.

Best Publications

  • A novel NMR method for determining the interfaces of large protein-protein complexes.

    Hideo Takahashi;Tamiji Nakanishi;Keiichiro Kami;Yoji Arata

  • Heterogeneity of the principal sigma factor in Escherichia coli: the rpoS gene product, sigma 38, is a second principal sigma factor of RNA polymerase in stationary-phase Escherichia coli.

    Kan Tanaka;Yuko Takayanagi;Nobuyuki Fujita;Akira Ishihama

  • Inorganic polyphosphate and the induction of rpoS expression

    Toshikazu Shiba;Kaori Tsutsumi;Hiroyuki Yano;Yoshiharu Ihara

  • Transcriptional activation of NtcA-dependent promoters of Synechococcus sp. PCC 7942 by 2-oxoglutarate in vitro.

    Ryohei Tanigawa;Masao Shirokane;Shin-ichi Maeda;Tatsuo Omata

  • Research lettersPrimary structure of the α-subunit of bovine adenylate cyclase-inhibiting G-protein deduced from the cDNA sequence

    Toshihide Nukada;Tsutomu Tanabe;Hideo Takahashi;Masaharu Noda

  • Identification of Ku70 and Ku80 homologues in Arabidopsis thaliana: evidence for a role in the repair of DNA double-strand breaks

    Katsunori Tamura;Yugo Adachi;Keiko Chiba;Keiko Oguchi

  • Characterization of three cDNA species encoding plastid RNA polymerase sigma factors in Arabidopsis thaliana: evidence for the sigma factor heterogeneity in higher plant plastids

    Kan Tanaka;Yuzuru Tozawa;Nobuyoshi Mochizuki;Kazuo Shinozaki

  • The Multiple-Stress Responsive Plastid Sigma Factor, SIG5, Directs Activation of the psbD Blue Light-Responsive Promoter (BLRP) in Arabidopsis thaliana

    Akitomo Nagashima;Mitsumasa Hanaoka;Toshiharu Shikanai;Makoto Fujiwara

  • An Arabidopsis sigma factor (SIG2)-dependent expression of plastid-encoded tRNAs in chloroplasts.

    Kengo Kanamaru;Akitomo Nagashima;Makoto Fujiwara;Hiroshi Shimada

  • Nucleotide sequence of the Bacillus subtilis phoR gene.

    T Seki;H Yoshikawa;H Takahashi;H Saito

  • Purification, characterization, and gene expression of all sigma factors of RNA polymerase in a cyanobacterium.

    Sousuke Imamura;Satoshi Yoshihara;Serina Nakano;Noriko Shiozaki

  • Nuclear Encoding of a Chloroplast RNA Polymerase Sigma Subunit in a Red Alga

    Kan Tanaka;Kosuke Oikawa;Niji Ohta;Haruko Kuroiwa

  • Molecular genetic analysis of chloroplast gene promoters dependent on SIG2, a nucleus-encoded sigma factor for the plastid-encoded RNA polymerase, in Arabidopsis thaliana.

    Mitsumasa Hanaoka;Kengo Kanamaru;Hideo Takahashi;Kan Tanaka

  • Cloning and nucleotide sequence of phoP, the regulatory gene for alkaline phosphatase and phosphodiesterase in Bacillus subtilis.

    T Seki;H Yoshikawa;H Takahashi;H Saito

  • Glutamyl‐tRNA mediates a switch in RNA polymerase use during chloroplast biogenesis

    Mitsumasa Hanaoka;Kengo Kanamaru;Kengo Kanamaru;Makoto Fujiwara;Hideo Takahashi

  • Multiple principal sigma factor homologs in eubacteria: identification of the "rpoD box"

    Kan Tanaka;Tetsuo Shiina;Hideo Takahashi

  • Structure of the 5' upstream region and the regulation of the rpoS gene of Escherichia coli.

    Y. Takayanagi;K. Tanaka;H. Takahashi

  • Promoter determinants for Escherichia coli RNA polymerase holoenzyme containing sigma 38 (the rpoS gene product).

    Kan Tanaka;Shuichi Kusano;Nobuyuki Fujita;Akira Ishihama

  • A sigma factor that modifies the circadian expression of a subset of genes in cyanobacteria.

    Nicholas F. Tsinoremas;Masahiro Ishiura;Takao Kondo;Carol R. Andersson

  • Plastidic RNA polymerase σ factors in Arabidopsis

    Kengo Kanamaru;Makoto Fujiwara;Motoaki Seki;Takeshi Katagiri

Frequent Co-Authors

Kan Tanaka
Kan Tanaka Tokyo Institute of Technology
Ichio Shimada
Ichio Shimada University of Tokyo
Yoji Arata
Yoji Arata University of Tokyo
Haruko Kuroiwa
Haruko Kuroiwa Japan Women's University
Masahiro Nishibori
Masahiro Nishibori Okayama University
Akira Ishihama
Akira Ishihama Hosei University
Tsuneyoshi Kuroiwa
Tsuneyoshi Kuroiwa Japan Women's University
Shigeyuki Kawano
Shigeyuki Kawano University of Tokyo
Daisuke Shibata
Daisuke Shibata Kyoto University

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