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Immunology

D-Index
60
Citations
11223
World Ranking
3352
National Ranking
1551

Overview

David W. Scott is affiliated with the Uniformed Services University of the Health Sciences in the United States. Their research intersects multiple areas within Medicine, spanning 97 publications that contribute to various subfields including Pathology and Forensic Medicine, Immunology, Oncology, Genetics, and Hematology.

Their recent work features papers published between 2020 and 2021 covering topics such as immune regulation, infectious diseases, and molecular diagnostics. Notable recent papers include:

  • Evaluating the quantity, quality and size distribution of cell-free DNA by multiplex droplet digital PCR (2020, Scientific Reports)
  • Engineered regulatory T cells expressing myelin-specific chimeric antigen receptors suppress EAE progression (2020, Cellular Immunology)
  • Tolerating Factor VIII: Recent Progress (2020, Frontiers in Immunology)
  • Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor (2020, Cellular Immunology)
  • Prospective Assessment of SARS-CoV-2 Seroconversion (PASS) study: an observational cohort study of SARS-CoV-2 infection and vaccination in healthcare workers (2021, BMC Infectious Diseases)

David W. Scott frequently collaborates with a core group of coauthors, including Kerry J. Savage, Diego Villa, Alina S. Gerrie, Laurie H. Sehn, and Pedro Farinha, with collaboration counts ranging from 13 to 18 publications per individual.

Their work appears predominantly in specialized journals and venues aligned with hematology and immunology. Frequent publication venues include:

  • Blood
  • Cellular Immunology
  • Frontiers in Immunology
  • Haematologica
  • UNC Libraries

Their research topics cover a wide scope within immune and hematologic diseases, with particular focus on:

  • Lymphoma Diagnosis and Treatment
  • CAR-T cell therapy research
  • Chronic Lymphocytic Leukemia Research
  • Immune Cell Function and Interaction
  • CNS Lymphoma Diagnosis and Treatment
  • Hemophilia Treatment and Research
  • T-cell and B-cell Immunology

David W. Scott's contributions reflect a blend of clinical and translational studies addressing immune cell dynamics, hematologic malignancies, and the application of engineered immunotherapies.

Best Publications

  • Immunogenicity of protein therapeutics

    Anne S. De Groot;David W. Scott

  • Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance

    Roberto A. Maldonado;Robert A. LaMothe;Joseph D. Ferrari;Ai-Hong Zhang

  • Activation of natural regulatory T cells by IgG Fc–derived peptide “Tregitopes”

    Anne S. De Groot;Leonard Moise;Julie A. McMurry;Erik Wambre

  • Activation-induced apoptosis in lymphocytes.

    Douglas R. Green;David W. Scott

  • Death the Fas way: regulation and pathophysiology of CD95 and its ligand.

    K Sharma;R.X Wang;L.Y Zhang;D.L Yin

  • Regulation of the G1 phase of the mammalian cell cycle

    Dubravka Donjerkovic;David W Scott

  • Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins

    Tie Chi Lei;David W. Scott

  • Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses.

    Yong Chan Kim;Ai-Hong Zhang;Yan Su;Sadiye Amcaoglu Rieder

  • FVIII-specific human chimeric antigen receptor T-regulatory cells suppress T- and B-cell responses to FVIII.

    Jeongheon Yoon;Anja Schmidt;Ai-Hong Zhang;Christoph Königs

  • Tregitope update: Mechanism of action parallels IVIg

    Leslie P. Cousens;Ryan Tassone;Bruce D. Mazer;Vasanthi Ramachandiran

  • Lymphoma models for B cell activation and tolerance. III. Cell cycle dependence for negative signalling of WEHI-231 B lymphoma cells by anti-mu.

    David W. Scott;Daniella Livnat;Christopher A. Pennell;Christopher A. Pennell;Peter Keng

  • Lymphoma models for B cell activation and tolerance. X. Anti-mu-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc.

    Gavin Fischer;Sally C. Kent;Luc Joseph;Doughs R. Green

  • In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity

    Leslie P. Cousens;Nader Najafian;Federico Mingozzi;Wassim Elyaman

  • Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis

    Rajeev K. Agarwal;Yubin Kang;Elias Zambidis;David W. Scott

  • Role of IgD in the immune response and tolerance. I. Anti-delta pretreatment facilitates tolerance induction in adult B cells in vitro.

    D W Scott;J E Layton;G J Nossal

  • Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases.

    Marco E. F. Melo;Jiahua Qian;Moustapha El-Amine;Rajeev K. Agarwal

  • Activation-induced cell death in B lymphocytes.

    Dubravka DONJERKOVIć;David W Scott

  • T cells commit suicide, but B cells are murdered!

    D. W. Scott;T. Grdina;Yufang Shi

  • Prostaglandin E2 induces apoptosis in immature normal and malignant B lymphocytes

    Deborah M. Brown;Garvin L. Warner;JoséE. Alés-Martínez;David W. Scott

  • Epitope-specific tolerance induction with an engineered immunoglobulin

    Elias T. Zambidis;David W. Scott

  • Engineered MBP-specific human Tregs ameliorate MOG-induced EAE through IL-2-triggered inhibition of effector T cells.

    Yong Chan Kim;Ai-Hong Zhang;Jeongheon Yoon;William E. Culp

Frequent Co-Authors

Anne S. De Groot
Anne S. De Groot University of Georgia
Richard P. Phipps
Richard P. Phipps University of Rochester
William J. Martin
William J. Martin National Institutes of Health
Federico Mingozzi
Federico Mingozzi Children's Hospital of Philadelphia
Yufang Shi
Yufang Shi Soochow University
Douglas R. Green
Douglas R. Green St. Jude Children's Research Hospital
Rachel R. Caspi
Rachel R. Caspi National Institutes of Health
Samia J. Khoury
Samia J. Khoury American University of Beirut
Ethan M. Shevach
Ethan M. Shevach National Institute of Allergy and Infectious Diseases
Omid C. Farokhzad
Omid C. Farokhzad Harvard Medical School

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