Derek A. Persons

Overview

Best Publications

• Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment

  Josef Priller;Alexander FLüGEL;T. I. M. Wehner;Matthias Boentert

  779
  Citations

• Altered growth regulation and enhanced tumorigenicity of NIH 3T3 fibroblasts transfected with protein kinase C-I cDNA

  Derek A. Persons;William O. Wilkison;Robert M. Bell;Olivera J. Finn

  395
  Citations

• Neogenesis of cerebellar Purkinje neurons from gene-marked bone marrow cells in vivo

  Josef Priller;Derek A. Persons;Francisco F. Klett;Gerd Kempermann

  366
  Citations

• Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells.

  Peiman Hematti;Bum Kee Hong;Cole Ferguson;Rima Adler

  328
  Citations

• Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis.

  Derek A. Persons;James A. Allay;Esther R. Allay;Richard A. Ashmun

  303
  Citations

• Comparison of Various Envelope Proteins for Their Ability to Pseudotype Lentiviral Vectors and Transduce Primitive Hematopoietic Cells from Human Blood

  Hideki Hanawa;Patrick F Kelly;Amit C Nathwani;Derek A Persons

  296
  Citations

• Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo

  Derek A. Persons;James A. Allay;Esther R. Allay;Richard J. Smeyne

  253
  Citations

• In vivo selection of retrovirally transduced hematopoietic stem cells

  James A. Allay;Derek A. Persons;Jacques Galipeau;Janice M. Riberdy

  241
  Citations

• Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus–based lentiviral vector system

  Hideki Hanawa;Peiman Hematti;Keyvan Keyvanfar;Mark E. Metzger

  229
  Citations

• The degree of phenotypic correction of murine β-thalassemia intermedia following lentiviral-mediated transfer of a human γ-globin gene is influenced by chromosomal position effects and vector copy number

  Derek A. Persons;Phillip W. Hargrove;Esther R. Allay;Hideki Hanawa

  225
  Citations

• Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities

  Andrew Wilber;Arthur W. Nienhuis;Derek A. Persons

  210
  Citations

• Hematopoietic cells and osteoblasts are derived from a common marrow progenitor after bone marrow transplantation

  Massimo Dominici;Colin Pritchard;John E. Garlits;Ted J. Hofmann

  204
  Citations

• Fv2 encodes a truncated form of the Stk receptor tyrosine kinase.

  Derek A. Persons;Robert F. Paulson;Melanie R. Loyd;Mark T. Herley

  194
  Citations

• Successful treatment of murine β-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells

  Derek A. Persons;Esther R. Allay;Nobukuni Sawai;Phillip W. Hargrove

  172
  Citations

• High-Efficiency Transduction and Long-Term Gene Expression with a Murine Stem Cell Retroviral Vector Encoding the Green Fluorescent Protein in Human Marrow Stromal Cells

  Jeffrey C. Marx;James A. Allay;Derek A. Persons;Sharon A. Nooner

  166
  Citations

• Extended β-globin locus control region elements promote consistent therapeutic expression of a γ-globin lentiviral vector in murine β-thalassemia

  Hideki Hanawa;Phillip W. Hargrove;Steven Kepes;Deo K. Srivastava

  161
  Citations

• Use of the green fluorescent protein as a marker to identify and track genetically modified hematopoietic cells

  Derek A Persons;James A Allay;Janice M Riberdy;Robert P Wersto

  155
  Citations

• Correction of Murine Sickle Cell Disease Using γ-Globin Lentiviral Vectors to Mediate High-level Expression of Fetal Hemoglobin

  Tamara I Pestina;Phillip W Hargrove;Dennis Jay;John T Gray

  145
  Citations

• Globin lentiviral vector insertions can perturb the expression of endogenous genes in beta-thalassemic hematopoietic cells.

  Phillip W Hargrove;Steven Kepes;Hideki Hanawa;John C Obenauer

  138
  Citations

• Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.

  Andrew Wilber;Phillip W. Hargrove;Yoon-Sang Kim;Janice M. Riberdy

  135
  Citations