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Stephen M. Jane

Stephen M. Jane

D-Index & Metrics

Molecular Biology

D-Index
50
Citations
9345
World Ranking
2572
National Ranking
61

Research.com Recognitions

  • 2015 - Fellow of the Australian Academy of Health and Medical Science

Overview

Stephen M. Jane is a researcher affiliated with Monash University in Australia, with a focus on medicine and biochemistry, genetics, and molecular biology. Their work extensively covers molecular biology, public health, oncology, hematology, and immunology.

The scientist's research topics include:

  • Acute Lymphoblastic Leukemia research
  • Cancer Cells and Metastasis
  • Chronic Myeloid Leukemia Treatments
  • Immune Cell Function and Interaction
  • Erythrocyte Function and Pathophysiology
  • Cancer-related gene regulation
  • Wnt/β-catenin signaling in development and cancer

Their recent notable publications include:

  • "YBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells," 2023, published in Nature Communications
  • "Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells," 2020, published in Nature Communications
  • "The Hsp70 chaperone system: distinct roles in erythrocyte formation and maintenance," 2021, published in Haematologica
  • "Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure," 2020, published in Disease Models & Mechanisms
  • "STAT5 activation promotes progression and chemotherapy-resistance in early T-cell precursor acute lymphoblastic leukemia," 2023, published in Blood

Frequent co-authors collaborating with Stephen M. Jane include:

  • Marina R. Carpinelli
  • Nadeem Hafeez Butt
  • Zihao Deng
  • David J. Curtis
  • Alana Auden

The scientist regularly publishes in venues such as Nature Communications, Developmental Dynamics, SSRN Electronic Journal, Blood, and Haematologica. Three of their publications have appeared in Nature Communications, while multiple works are found in Developmental Dynamics and SSRN Electronic Journal.

Stephen M. Jane was recognized as a Fellow of the Australian Academy of Health and Medical Science in 2015.

Best Publications

  • PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

    Quan Zhao;Quan Zhao;Gerhard Rank;Yuen T Tan;Haitao Li

  • Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium.

    Joachim R. Göthert;Sonja E. Gustin;J. Anke M. van Eekelen;Uli Schmidt

  • A Homolog of Drosophila grainy head Is Essential for Epidermal Integrity in Mice

    Stephen B. Ting;Jacinta Caddy;Nikki Hislop;Tomasz Wilanowski

  • Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis.

    Derek A. Persons;James A. Allay;Esther R. Allay;Richard A. Ashmun

  • The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12

    Mark A. Hall;David J. Curtis;Donald Metcalf;Andrew G. Elefanty

  • The Lmo2 Oncogene Initiates Leukemia in Mice by Inducing Thymocyte Self-Renewal

    Matthew P. McCormack;Matthew P. McCormack;Lauren F. Young;Sumitha Vasudevan;Carolyn A. de Graaf

  • Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis

    Charbel Darido;Smitha R. Georgy;Tomasz Wilanowski;Sebastian Dworkin

  • Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors

    Nicole M Haynes;Joseph A Trapani;Michèle W L Teng;Jacob T Jackson

  • Epidermal wound repair is regulated by the planar cell polarity signaling pathway

    Jacinta Caddy;Tomasz Wilanowski;Charbel Darido;Sebastian Dworkin

  • Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma.

    Nicole M. Haynes;Marie B. Snook;Joseph A. Trapani;Loretta Cerruti

  • Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner.

    Paul A. Ney;Nancy C. Andrews;Stephen M. Jane;Brian Safer

  • The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge.

    Lukas E. Dow;Lukas E. Dow;Jeff S. Kauffman;Jacinta Caddy;A. S. Peterson

  • Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3.

    Stephen Bek Ngie Ting;Tomasz Wilanowski;Alana Auden;Mark A Hall

  • A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead.

    Tomasz Wilanowski;Annabel Tuckfield;Loretta Cerruti;Sinead O'Connell

  • Identification of a stage selector element in the human gamma-globin gene promoter that fosters preferential interaction with the 5' HS2 enhancer when in competition with the beta-promoter.

    Stephen M. Jane;Paul A. Ney;Elio F. Vanin;Deborah L. Gumucio

  • Rejection of syngeneic colon carcinoma by CTLs expressing single-chain antibody receptors codelivering CD28 costimulation.

    Nicole M. Haynes;Joseph A. Trapani;Michele W. L. Teng;Jacob T. Jackson

  • Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development.

    Alana Auden;Jacinta Caddy;Tomasz Wilanowski;Stephen B. Ting

  • Perturbed desmosomal cadherin expression in grainy head-like 1-null mice

    Tomasz Wilanowski;Jacinta Caddy;Stephen B Ting;Nikki R Hislop

  • Methylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression.

    Stephen M. Jane;Deborah L. Gumucio;Paul A. Ney;John M. Cunningham

  • Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein.

    S.M. Jane;A.W. Nienhuis;J.M. Cunningham

Frequent Co-Authors

Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Phillip K. Darcy
Phillip K. Darcy Peter MacCallum Cancer Centre
Benjamin T. Kile
Benjamin T. Kile University of Adelaide
Joseph A. Trapani
Joseph A. Trapani Peter MacCallum Cancer Centre
Peter J. Anderson
Peter J. Anderson Monash University
Michael H. Kershaw
Michael H. Kershaw Peter MacCallum Cancer Centre
Michele W. L. Teng
Michele W. L. Teng QIMR Berghofer Medical Research Institute
Douglas J. Hilton
Douglas J. Hilton Walter and Eliza Hall Institute of Medical Research
Phillip J. Robinson
Phillip J. Robinson Children's Medical Research Institute
Simon J. Foote
Simon J. Foote Australian National University

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