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Andrew C. Perkins

Andrew C. Perkins

D-Index & Metrics

Molecular Biology

D-Index
47
Citations
11316
World Ranking
2725
National Ranking
67

Overview

Andrew C. Perkins is affiliated with Monash University in Australia. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology, with a primary focus on hematology and genetics.

Their work covers key subfields including hematology, genetics, molecular biology, rheumatology, and immunology. The main topics addressed in their research are:

  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Chronic Myeloid Leukemia Treatments
  • Kruppel-like factors research
  • Acute Myeloid Leukemia Research
  • Eosinophilic Disorders and Syndromes
  • Immune cells in cancer
  • Platelet Disorders and Treatments

The scientist has contributed notably to a range of publications. Some recent papers include:

  • Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance, 2020, Nature Communications
  • Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study, 2023, The Lancet
  • Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues, 2021, Cell Reports
  • The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1, 2020, Blood
  • The Role of LNK (SH2B3) in the Regulation of JAK-STAT Signalling in Haematopoiesis, 2021, Pharmaceuticals

Their frequent co-authors include:

  • Jean-Jacques Kiladjian
  • María Laura Fox
  • Srđan Verstovšek
  • Ruben A. Mesa
  • Donal P. McLornan

In terms of publication venues, Andrew C. Perkins has an extensive record in:

  • Blood
  • Clinical Lymphoma Myeloma & Leukemia
  • Nature Communications
  • Journal of Clinical Oncology
  • HemaSphere

Their research focus on hematologic malignancies and related molecular pathways is demonstrated by numerous publications in respected journals specializing in oncology, hematology, and molecular biology.

Best Publications

  • Stem cell transcriptome profiling via massive-scale mRNA sequencing.

    Nicole Cloonan;Alistair R R Forrest;Alistair R R Forrest;Gabriel Kolle;Brooke B A Gardiner

  • Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation

    Marcel E. Dinger;Paulo P. Amaral;Tim R. Mercer;Ken C. Pang;Ken C. Pang

  • Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

    Perkins Ac;Sharpe Ah;Orkin Sh;Orkin Sh

  • An essential role in liver development for transcription factor XBP-1

    Andreas M. Reimold;Amit Etkin;Isabelle Clauss;Andrew Perkins

  • High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

    Max Gulhane;Lydia Murray;Rohan Lourie;Hui Tong

  • Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial

    Ruben A. Mesa;Alessandro M. Vannucchi;Adam Mead;Miklos Egyed

  • ISOLATION AND CHARACTERIZATION OF THE CDNA ENCODING BKLF/TEF-2, A MAJOR CACCC-BOX-BINDING PROTEIN IN ERYTHROID CELLS AND SELECTED OTHER CELLS

    Merlin Crossley;Emma Whitelaw;Andrew Perkins;Greg Williams

  • A Global Role for EKLF in Definitive and Primitive Erythropoiesis

    Denise Hodge;Elise Coghill;Elise Coghill;Janelle Keys;Janelle Keys;Tina Maguire;Tina Maguire

  • A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells

    Michael R. Tallack;Tom Whitington;Wai Shan Yuen;Elanor N. Wainwright

  • Complex architecture and regulated expression of the Sox2ot locus during vertebrate development

    Paulo P. Amaral;Christine Neyt;Simon J. Wilkins;Marjan E. Askarian-Amiri

  • SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis

    Soula Ganiatsas;Lia Kwee;Yuko Fujiwara;Andrew Perkins

  • Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor

    Mark W. Kieran;Andrew C. Perkins;Stuart H. Orkin;Stuart H. Orkin;Leonard I. Zon;Leonard I. Zon

  • Evolution of gene function and regulatory control after whole-genome duplication: Comparative analyses in vertebrates

    Karin Sonja Kassahn;Vinh Toan Dang;Simon J. Wilkins;Andrew C. Perkins

  • Targeted Disruption of the Basic Krüppel-Like Factor Gene (Klf3) Reveals a Role in Adipogenesis

    Nancy Sue;Briony H. A. Jack;Sally A. Eaton;Richard C. M. Pearson

  • Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia.

    Andrew Perkins;Kritaya Kongsuwan;Jane Visvader;Jerry M. Adams

  • Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF.

    Andrew C. Perkins;Karin M. L. Gaensler;Stuart H. Orkin;Stuart H. Orkin

  • Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease

    Hao Lu;Maria C Rondón Galeano;Elisabeth Ott;Geraldine Kaeslin

  • Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor.

    Peter Papathanasiou;Andrew C. Perkins;Bradley S. Cobb;Roger Ferrini

  • Krüppeling erythropoiesis: An unexpected broad spectrum of human red blood cell disorders due to KLF1 variants

    Andrew Perkins;Xiangmin Xu;Douglas R. Higgs;George P. Patrinos

  • Human KLF17 is a new member of the Sp/KLF family of transcription factors.

    Jane van Vliet;Linda A. Crofts;Kate G.R. Quinlan;Robert Czolij

Frequent Co-Authors

Sean M. Grimmond
Sean M. Grimmond University of Melbourne
Merlin Crossley
Merlin Crossley University of New South Wales
Stuart H. Orkin
Stuart H. Orkin Harvard University
Jean-Pierre Levesque
Jean-Pierre Levesque University of Queensland
Timothy L. Bailey
Timothy L. Bailey University of Nevada Reno
Leonard I. Zon
Leonard I. Zon Harvard University
Claire N. Harrison
Claire N. Harrison Guy's and St Thomas' NHS Foundation Trust
Alessandro M. Vannucchi
Alessandro M. Vannucchi University of Florence
Luanne L. Peters
Luanne L. Peters The Jackson Laboratory
David A. Hume
David A. Hume University of Queensland

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