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Biology and Biochemistry

D-Index
65
Citations
19062
World Ranking
9022
National Ranking
4010

Overview

James Palis is a researcher affiliated with the University of Rochester Medical Center in the United States. Their work mainly spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable specialization in Molecular Biology, Hematology, Physiology, Immunology, and Pulmonary and Respiratory Medicine.

The scientist's research focuses on a range of topics including:

  • Erythrocyte Function and Pathophysiology
  • Single-cell and spatial transcriptomics
  • Zebrafish Biomedical Research Applications
  • Platelet Disorders and Treatments
  • Immune Cell Function and Interaction
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation

James Palis has contributed extensively to scientific knowledge through various publications. Some recent papers include:

  • A human cell atlas of fetal gene expression, 2020, Science
  • Lung megakaryocytes are immune modulatory cells, 2020, Journal of Clinical Investigation
  • Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development, 2020, Developmental Cell
  • Yolk sac cell atlas reveals multiorgan functions during human early development, 2023, Science
  • Modeling human yolk sac hematopoiesis with pluripotent stem cells, 2021, The Journal of Experimental Medicine

Their frequent co-authors include:

  • Kathleen E. McGrath
  • Paul D. Kingsley
  • Laurie A. Steiner
  • Lionel Blanc
  • Patrick G. Gallagher

James Palis's publications often appear in notable journals such as:

  • Blood
  • Experimental Hematology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Journal of Clinical Investigation

Best Publications

  • Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

    Adriana Donovan;Alison Brownlie;Alison Brownlie;Yi Zhou;Jennifer Shepard

  • Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse.

    James Palis;Scott Robertson;Marion Kennedy;Charles Wall

  • Haemangioblast commitment is initiated in the primitive streak of the mouse embryo.

    Tara L. Huber;Valerie Kouskoff;Valerie Kouskoff;H. Joerg Fehling;James Palis

  • Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.

    Kathleen E. McGrath;Anne D. Koniski;Kathleen M. Maltby;Judeth K. McGann

  • A human cell atlas of fetal gene expression

    Junyue Cao;Diana R. O’Day;Hannah A. Pliner;Paul D. Kingsley

  • Yolk-sac hematopoiesis: The first blood cells of mouse and man

    James Palis;Mervin C Yoder

  • Primitive and definitive erythropoiesis in mammals

    James Palis

  • A heme export protein is required for red blood cell differentiation and iron homeostasis

    Siobán B. Keel;Raymond T. Doty;Zhantao Yang;John G. Quigley

  • Deficiency of glutaredoxin 5 reveals Fe–S clusters are required for vertebrate haem synthesis

    Rebecca A. Wingert;Jenna L. Galloway;Bruce Barut;Helen Foott

  • Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo

    Kathleen E. McGrath;Jenna M. Frame;Katherine H. Fegan;James R. Bowen

  • The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis.

    Joanna M. Tober;Anne Koniski;Kathleen E McGrath;Radhika Vemishetti

  • Circulation is established in a stepwise pattern in the mammalian embryo

    Kathleen E. McGrath;Anne D. Koniski;Jeffrey Malik;James Palis

  • Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro.

    Georges Lacaud;Lia Gore;Marion Kennedy;Valerie Kouskoff

  • All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac

    Christopher Thomas Lux;Momoko Yoshimoto;Kathleen McGrath;Simon J. Conway

  • Yolk sac–derived primitive erythroblasts enucleate during mammalian embryogenesis

    Paul D. Kingsley;Jeffrey Malik;Katherine A. Fantauzzo;James Palis

  • cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes

    Alan J. Davidson;Patricia Ernst;Yuan Wang;Marcus P. S. Dekens

  • Lineage analysis of the hemangioblast as defined by FLK1 and SCL expression.

    Yun Shin Chung;Wen Jie Zhang;Elizabeth Arentson;Paul D. Kingsley

  • Initiation of hematopoiesis and vasculogenesis in murine yolk sac explants.

    James Palis;Kathleen E. McGrath;Paul D. Kingsley

  • Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis

    Roland Nilsson;Iman J. Schultz;Iman J. Schultz;Eric Adam Pierce;Eric Adam Pierce;Kathleen A. Soltis;Kathleen A. Soltis

  • Developmental biology of erythropoiesis.

    J. Palis;G.B. Segel

Frequent Co-Authors

Barry H. Paw
Barry H. Paw Brigham and Women's Hospital
Leonard I. Zon
Leonard I. Zon Harvard University
Stuart H. Orkin
Stuart H. Orkin Harvard University
Jerry Kaplan
Jerry Kaplan University of Utah
Daniel E. Bauer
Daniel E. Bauer Harvard University
Diane M. Ward
Diane M. Ward University of Utah
Alan B. Cantor
Alan B. Cantor Harvard University
Stephen D. Dertinger
Stephen D. Dertinger University of Rochester
Gordon Keller
Gordon Keller University of Toronto

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