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Brigitte Gasser

Brigitte Gasser

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
9942
World Ranking
16670
National Ranking
150

Overview

Brigitte Gasser is affiliated with BOKU University in Austria and has contributed extensively to the field of biochemistry, genetics, and molecular biology, with a particular focus on molecular biology within this broader discipline. Their research spans multiple subfields including biomedical engineering, cell biology, food science, and biotechnology.

The scientist's work covers a range of topics primarily centered on fungal and yeast genetics research, microbial metabolic engineering and bioproduction, and viral infectious diseases alongside gene expression in insects. Additional topics explored include biofuel production and bioconversion, fermentation and sensory analysis, transgenic plants and their applications, and gene regulatory network analysis.

Their frequent publication outlets reflect a strong focus on biotechnology and microbiology, with multiple articles appearing in venues such as FEMS Yeast Research, New Biotechnology, Trends in Biotechnology, Metabolic Engineering, and Biotechnology Journal.

Notable recent papers include:

  • Microbial protein cell factories fight back? (2021, Trends in Biotechnology)
  • Microbe Profile: Komagataella phaffii: a methanol devouring biotech yeast formerly known as Pichia pastoris (2020, Microbiology)
  • What makes Komagataella phaffii non-conventional? (2021, FEMS Yeast Research)
  • Going beyond the limit: Increasing global translation activity leads to increased productivity of recombinant secreted proteins in Pichia pastoris (2022, Metabolic Engineering)
  • Synthetic activation of yeast stress response improves secretion of recombinant proteins (2023, New Biotechnology)

Collaborative research has been conducted with several frequent coauthors, including Diethard Mattanovich, Corinna Rebnegger, Arianna Palma, Sonakshi De, and Viktoria Kowarz. The volume of joint work with these colleagues indicates ongoing partnerships within their scientific network.

Best Publications

  • Recombinant Protein Production in Yeasts

    Diethard Mattanovich;Paola Branduardi;Laura Dato;Brigitte Gasser

  • Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview

    Brigitte Gasser;Markku Saloheimo;Ursula Rinas;Martin Dragosits

  • Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris.

    Hubertus Hohenblum;Brigitte Gasser;Michael Maurer;Nicole Borth

  • The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO 2

    Thomas Gassler;Michael Sauer;Brigitte Gasser;Michael Egermeier

  • Stress in recombinant protein producing yeasts.

    Diethard Mattanovich;Brigitte Gasser;Hubertus Hohenblum;Michael Sauer

  • Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris.

    Diethard Mattanovich;Alexandra Graf;Johannes Stadlmann;Martin Dragosits

  • Pichia pastoris: protein production host and model organism for biomedical research

    Brigitte Gasser;Roland Prielhofer;Hans Marx;Michael Maurer

  • The effect of temperature on the proteome of recombinant Pichia pastoris

    Martin Dragosits;Johannes Stadlmann;Joan Albiol;Kristin Baumann

  • The secretory pathway: exploring yeast diversity

    Marizela Delic;Minoska Valli;Alexandra B. Graf;Martin Pfeffer

  • Engineering of Pichia pastoris for improved production of antibody fragments.

    Brigitte Gasser;Michael Maurer;Johannes Gach;Renate Kunert

  • Metabolic engineering of Pichia pastoris.

    David A. Peña;Brigitte Gasser;Jürgen Zanghellini;Matthias G. Steiger

  • Quo vadis? The challenges of recombinant protein folding and secretion in Pichia pastoris

    Verena Puxbaum;Diethard Mattanovich;Brigitte Gasser

  • A multi-level study of recombinant Pichia pastoris in different oxygen conditions

    Kristin Baumann;Marc Carnicer;Martin Dragosits;Alexandra B Graf

  • Transcriptomics-Based Identification of Novel Factors Enhancing Heterologous Protein Secretion in Yeasts

    Brigitte Gasser;Michael Sauer;Michael Maurer;Gerhard Stadlmayr

  • Induction without methanol: novel regulated promoters enable high-level expression in Pichia pastoris.

    Roland Prielhofer;Michael Maurer;Joachim Klein;Jana Wenger

  • Identification and characterisation of novel Pichia pastoris promoters for heterologous protein production.

    Gerhard Stadlmayr;Astrid Mecklenbräuker;Marion Rothmüller;Michael Maurer

  • Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions

    Brigitte Gasser;Michael Maurer;Jari Rautio;Michael Sauer

  • GoldenPiCS: a Golden Gate-derived modular cloning system for applied synthetic biology in the yeast Pichia pastoris.

    Roland Prielhofer;Juan J. Barrero;Stefanie Steuer;Stefanie Steuer;Thomas Gassler

  • Directed gene copy number amplification in Pichia pastoris by vector integration into the ribosomal DNA locus

    Hans Marx;Astrid Mecklenbräuker;Brigitte Gasser;Michael Sauer

  • Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics.

    José Luis Corchero;Brigitte Gasser;David Resina;Wesley Smith

Frequent Co-Authors

Diethard Mattanovich
Diethard Mattanovich BOKU University
Michael Sauer
Michael Sauer University of Potsdam
Friedrich Altmann
Friedrich Altmann BOKU University
Stephan Hann
Stephan Hann BOKU University
Gunda Koellensperger
Gunda Koellensperger University of Vienna
Danilo Porro
Danilo Porro University of Milano-Bicocca
Johannes Stadlmann
Johannes Stadlmann BOKU University
Renate Kunert
Renate Kunert BOKU University
Günther Daum
Günther Daum Graz University of Technology
Markku Saloheimo
Markku Saloheimo VTT Technical Research Centre of Finland

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