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Biology and Biochemistry

D-Index
58
Citations
10992
World Ranking
13284
National Ranking
942

Overview

Ursula Rinas is a researcher affiliated with the University of Hannover in Germany. Their scholarly work primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with specific emphasis on Molecular Biology and Genetics. They also explore Materials Chemistry, Ecology, and Biomedical Engineering as subfields of study.

Their research topics cover several areas including:

  • Microbial Metabolic Engineering and Bioproduction
  • Enzyme Structure and Function
  • Bacterial Genetics and Biotechnology
  • RNA and protein synthesis mechanisms
  • Protein Structure and Dynamics
  • Cancer, Hypoxia, and Metabolism
  • Pancreatic function and diabetes

Rinas has contributed papers to several publication venues with repeated presence in:

  • Microbial Cell Factories
  • Biotechnology and Bioengineering
  • Biochemical Engineering Journal
  • Journal of Biomedical Materials Research Part A
  • Engineering Reports

Recent papers include:

  • "Recombinant protein production associated growth inhibition results mainly from transcription and not from translation," 2020, Microbial Cell Factories
  • "Recombinant protein production-associated metabolic burden reflects anabolic constraints and reveals similarities to a carbon overfeeding response," 2020, Biotechnology and Bioengineering
  • "Increased glycosylated l-asparaginase production through selection of Pichia pastoris platform and oxygen-methanol control in fed-batches," 2021, Biochemical Engineering Journal
  • "Varying the sustained release of BMP-2 from chitosan nanogel-functionalized polycaprolactone fiber mats by different polycaprolactone surface modifications," 2020, Journal of Biomedical Materials Research Part A
  • "Is energy excess the initial trigger of carbon overflow metabolism? Transcriptional network response of carbon-limited Escherichia coli to transient carbon excess," 2022, Microbial Cell Factories

Frequent coauthors of Ursula Rinas are:

  • Zhaopeng Li
  • Bastian Quaas
  • Andrea Hoffmann
  • Frank Klawonn
  • Thomas Scheper

Best Publications

  • Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88

    Herman J. Pel;Johannes H. De Winde;Johannes H. De Winde;David B. Archer;Paul S. Dyer

  • Simple fed-batch technique for high cell density cultivation of Escherichia coli.

    D.J. Korz;U. Rinas;K. Hellmuth;E.A. Sanders

  • Strategies for the recovery of active proteins through refolding of bacterial inclusion body proteins.

    Luis Felipe Vallejo;Ursula Rinas

  • Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview

    Brigitte Gasser;Markku Saloheimo;Ursula Rinas;Martin Dragosits

  • Stress induced by recombinant protein production in Escherichia coli.

    Frank Hoffmann;Ursula Rinas

  • Metabolic flux analysis of Escherichia coli in glucose-limited continuous culture. I. Growth-rate-dependent metabolic efficiency at steady state.

    Anke Kayser;Jan Weber;Volker Hecht;Ursula Rinas

  • Renaturation and purification of bone morphogenetic protein-2 produced as inclusion bodies in high-cell-density cultures of recombinant Escherichia coli.

    Luis Felipe Vallejo;Maren Brokelmann;Sabine Marten;Susanne Trappe

  • Metabolic costs of amino acid and protein production in Escherichia coli.

    Christoph Kaleta;Sascha Schäuble;Ursula Rinas;Stefan Schuster

  • Bacterial Inclusion Bodies: Discovering Their Better Half.

    Ursula Rinas;Elena Garcia-Fruitós;José Luis Corchero;Esther Vázquez

  • Expression of intracellular hemoglobin improves protein synthesis in oxygen-limited Escherichia coli.

    Chaitan Khosla;Joseph E. Curtis;John DeModena;Ursula Rinas

  • The intra- and extracellular proteome of Aspergillus niger growing on defined medium with xylose or maltose as carbon substrate

    Xin-xin Lu;Jibin Sun;Manfred Nimtz;Josef Wissing

  • Physiological response of Pichia pastoris GS115 to methanol-induced high level production of the Hepatitis B surface antigen: catabolic adaptation, stress responses, and autophagic processes

    Ana Leticia Vanz;Heinrich Lünsdorf;Ahmad Adnan;Manfred Nimtz

  • Optimized procedure for renaturation of recombinant human bone morphogenetic protein‐2 at high protein concentration

    Luis Felipe Vallejo;Ursula Rinas

  • Simple high-cell density fed-batch technique for high-level recombinant protein production with Pichia pastoris: Application to intracellular production of Hepatitis B surface antigen.

    Chandrasekhar Gurramkonda;Ahmad Adnan;Thomas Gäbel;Heinrich Lünsdorf

  • The effect of an rhBMP-2 absorbable collagen sponge-targeted system on bone formation in vivo

    Rick Visser;Pilar M. Arrabal;Jose Becerra;Ursula Rinas

  • Metabolic flux analysis of Escherichia coli in glucose-limited continuous culture. II. Dynamic response to famine and feast, activation of the methylglyoxal pathway and oscillatory behaviour

    Jan Weber;Anke Kayser;Ursula Rinas

  • Side effects of chaperone gene co-expression in recombinant protein production

    Mónica Martínez-Alonso;Elena García-Fruitós;Neus Ferrer-Miralles;Ursula Rinas

  • Application of simple fed-batch technique to high-level secretory production of insulin precursor using Pichia pastoris with subsequent purification and conversion to human insulin

    Chandrasekhar Gurramkonda;Sulena Polez;Natasa Skoko;Ahmad Adnan

  • The metabolic potential of Escherichia coli BL21 in defined and rich medium

    Zhaopeng Li;Manfred Nimtz;Ursula Rinas

  • Simple defined autoinduction medium for high-level recombinant protein production using T7-based Escherichia coli expression systems

    Zhaopeng Li;Wolfgang Kessler;Joop van den Heuvel;Ursula Rinas

Frequent Co-Authors

Antonio Villaverde
Antonio Villaverde Autonomous University of Barcelona
Esther Vázquez
Esther Vázquez Autonomous University of Barcelona
Manfred Nimtz
Manfred Nimtz Helmholtz Centre for Infection Research
Andreas Seidel-Morgenstern
Andreas Seidel-Morgenstern Max Planck Society
Heinrich Lünsdorf
Heinrich Lünsdorf Helmholtz Centre for Infection Research
An-Ping Zeng
An-Ping Zeng Hamburg University of Technology
Axel Schambach
Axel Schambach Hannover Medical School
Ulrich Martin
Ulrich Martin Hannover Medical School
Frank Hoffmann
Frank Hoffmann TU Dortmund University

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