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Biology and Biochemistry

D-Index
79
Citations
18233
World Ranking
4401
National Ranking
327

Overview

Manfred Nimtz is affiliated with the Helmholtz Centre for Infection Research in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a particular emphasis on molecular biology within these fields.

They have contributed to diverse subfields such as endocrinology, genetics, molecular medicine, and renewable energy, sustainability, and the environment. The main topics covered by their work include porphyrin metabolism and disorders, bacterial genetics and biotechnology, bacterial biofilms and quorum sensing, antibiotic resistance in bacteria, Legionella and Acanthamoeba research, metalloenzymes and iron-sulfur proteins, and metal-catalyzed oxygenation mechanisms.

Recent scientific publications by Manfred Nimtz include the following:

  • Insights into polyamine metabolism: homospermidine is double-oxidized in two discrete steps by a single copper-containing amine oxidase in pyrrolizidine alkaloid biosynthesis (2022, The Plant Cell)
  • Clarithromycin Exerts an Antibiofilm Effect against Salmonella enterica Serovar Typhimurium rdar Biofilm Formation and Transforms the Physiology towards an Apparent Oxygen-Depleted Energy and Carbon Metabolism (2020, Infection and Immunity)
  • Mg-protoporphyrin IX monomethyl ester cyclase from Rhodobacter capsulatus: radical SAM-dependent synthesis of the isocyclic ring of bacteriochlorophylls (2020, Biochemical Journal)
  • Transcriptional network analysis identifies key elements governing the recombinant protein production provoked reprogramming of carbon and energy metabolism in Escherichia coli BL21 ( DE3 ) (2021, Engineering Reports)
  • Crystal structure of NirF: insights into its role in heme d 1 biosynthesis (2020, FEBS Journal)

Their frequent co-authors include:

  • Lothar Jänsch
  • Sulman Shafeeq
  • Ute Römling
  • M. Iqbal Choudhary
  • Mariam Esmaeeli

Manfred Nimtz has published in several notable scientific venues, with recurrent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Plant Cell
  • Infection and Immunity
  • Biochemical Journal
  • Engineering Reports

Best Publications

  • GGDEF and EAL domains inversely regulate cyclic di-GMP levels and transition from sessility to motility.

    Roger Simm;Michael Morr;Abdul Kader;Manfred Nimtz

  • The multicellular morphotypes of Salmonella typhimurium and Escherichia coli produce cellulose as the second component of the extracellular matrix.

    Xhavit Zogaj;Manfred Nimtz;Manfred Rohde;Werner Bokranz

  • Production of Cellulose and Curli Fimbriae by Members of the Family Enterobacteriaceae Isolated from the Human Gastrointestinal Tract

    Xhavit Zogaj;Werner Bokranz;Manfred Nimtz;Ute Römling

  • The Pseudomonas aeruginosa quinolone signal (PQS) has an iron‐chelating activity

    Florian Bredenbruch;Robert Geffers;Manfred Nimtz;Jan Buer

  • Cross-feeding and interkingdom communication in dual-species biofilms of Streptococcus mutans and Candida albicans.

    Helena Sztajer;Szymon P Szafranski;Jürgen Tomasch;Michael Reck

  • An efficient method for anchoring fmoc-anino acids to hydroxyl-functionalised solid supports

    Birgit Blankemeyer-Menge;Manfred Nimtz;Ronald Frank

  • Purification and chemical characterization of beta-trace protein from human cerebrospinal fluid: its identification as prostaglandin D synthase.

    Andrea Hoffmann;Harald S. Conradt;Gerhard Gross;Manfred Nimtz

  • Structures of sialylated oligosaccharides of human erythropoietin expressed in recombinant BHK‐21 cells

    Manfred Nimtz;Wolfgang Martin;Victor Wray;Klaus‐Dieter Klöppel

  • Genetic engineering of recombinant glycoproteins and the glycosylation pathway in mammalian host cells.

    Eckart Grabenhorst;Peter Schlenke;Susanne Pohl;Manfred Nimtz

  • Occurrence and regulation of the multicellular morphotype in Salmonella serovars important in human disease.

    Ute Römling;Werner Bokranz;Wolfgang Rabsch;Xhavit Zogaj

  • The MprF protein is required for lysinylation of phospholipids in listerial membranes and confers resistance to cationic antimicrobial peptides (CAMPs) on Listeria monocytogenes

    Kathrin Thedieck;Torsten Hain;Walid Mohamed;Brian J Tindall

  • Internal architecture of mitochondrial complex I from Arabidopsis thaliana.

    Jennifer Klodmann;Stephanie Sunderhaus;Manfred Nimtz;Lothar Jänsch

  • Engineering the protein N-glycosylation pathway in insect cells for production of biantennary, complex N-glycans.

    Jason Hollister;Eckart Grabenhorst;Manfred Nimtz;Harald Conradt

  • Bovine Adrenals Contain, in Addition to Ouabain, a Second Inhibitor of the Sodium Pump

    Ralf Schneider;Victor Wray;Manfred Nimtz;Wolf Dieter Lehmann

  • Temperature reduction in cultures of hGM-CSF-expressing CHO cells: effect on productivity and product quality

    Mariela Bollati-Fogolín;Guillermina Forno;Manfred Nimtz;Harald S. Conradt

  • Molecular characterization of β-trace protein in human serum and urine: a potential diagnostic marker for renal diseases

    Andrea Hoffmann;Manfred Nimtz;Harald S. Conradt

  • Purification and Characterization of a Cytotoxic Exolipid of Burkholderia pseudomallei

    S. Häußler;M. Nimtz;T. Domke;V. Wray

  • Male-specific modification of human CD52.

    Sabine Schröter;Petra Derr;Harald S. Conradt;Manfred Nimtz

  • Formation and analysis of mannosylerythritol lipids secreted by Pseudozyma aphidis.

    U. Rau;L. A. Nguyen;S. Schulz;V. Wray

  • Biosynthetic Pathway of Pseudomonas aeruginosa 4-Hydroxy-2-Alkylquinolines

    Florian Bredenbruch;Manfred Nimtz;Victor Wray;Michael Morr

Frequent Co-Authors

Victor Wray
Victor Wray Heinrich Heine University Düsseldorf
Ute Römling
Ute Römling Karolinska Institute
Ursula Rinas
Ursula Rinas University of Hannover
Dieter Strack
Dieter Strack Leibniz Association
Silke Leimkühler
Silke Leimkühler University of Potsdam
Jürgen Schmidt
Jürgen Schmidt Leibniz Association
Heinrich Lünsdorf
Heinrich Lünsdorf Helmholtz Centre for Infection Research
Susanne Häussler
Susanne Häussler Helmholtz Centre for Infection Research
Klaus Geider
Klaus Geider Max Planck Society
Juan J. Calvete
Juan J. Calvete Spanish National Research Council

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