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Biology and Biochemistry

D-Index
68
Citations
14498
World Ranking
7896
National Ranking
3583

Overview

Gerard Apodaca is affiliated with the University of Pittsburgh in the United States. Their research spans several interconnected fields, primarily within medicine and biochemistry, genetics, and molecular biology. The scientist's work includes a focus on molecular biology, physiology, urology, surgery, and sensory systems.

Their research topics cover diverse areas such as erythrocyte function and pathophysiology, urinary bladder and prostate research, tissue engineering and regenerative medicine, ion transport and channel regulation, ion channel regulation and function, urological disorders and treatments, and ion channels and receptors.

Gerard Apodaca has contributed to multiple scientific papers with notable titles including:

  • The Urothelium: Life in a Liquid Environment, 2020, Physiological Reviews
  • Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception, 2021, JCI Insight
  • 3D printed biaxial stretcher compatible with live fluorescence microscopy, 2020, HardwareX
  • The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice, 2022, JCI Insight
  • Bladder infection with uropathogenic Escherichia coli increases the excitability of afferent neurons, 2021, American Journal of Physiology-Renal Physiology

Frequent co-authors collaborating with Gerard Apodaca include:

  • Marianela G. Dalghi
  • Marcelo D. Carattino
  • Nicolás Montalbetti
  • Wily G. Ruiz
  • Dennis R. Clayton

The scientist's work is often published in journals such as:

  • Journal of Visualized Experiments
  • American Journal of Physiology-Renal Physiology
  • JCI Insight
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Physiology

Gerard Apodaca's research integrates molecular biology techniques and physiological analysis with a focus on urological systems and their sensory properties. This includes detailed investigations into cellular and molecular mechanisms related to urothelial function and the regulation of ion channels affecting bladder and urinary tract physiology.

Best Publications

  • Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1

    L.A. Birder;Y. Nakamura;Y. Nakamura;S. Kiss;M.L. Nealen

  • Endocytic Traffic in Polarized Epithelial Cells: Role of the Actin and Microtubule Cytoskeleton

    Gerard Apodaca

  • Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes.

    G Apodaca;L A Katz;K E Mostov

  • The Uroepithelium: Not Just a Passive Barrier

    Gerard Apodaca

  • Cell biology and physiology of the uroepithelium.

    Puneet Khandelwal;Soman Ninan Abraham;Gerard Apodaca

  • The extracellular matrix of the central and peripheral nervous systems: structure and function

    James T. Rutka;Gerard Apodaca;Robert Stern;Mark Rosenblum

  • An autonomous signal for basolateral sorting in the cytoplasmic domain of the polymeric immunoglobulin receptor

    J.E. Casanova;G. Apodaca;K.E. Mostov

  • Immunoglobulin transport across polarized epithelial cells.

    Raul Rojas;Gerard Apodaca

  • Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder

    Lori A. Birder;Gerard Apodaca;William C. De Groat;Anthony J. Kanai

  • Plasma membrane protein sorting in polarized epithelial cells.

    K Mostov;G Apodaca;B Aroeti;C Okamoto

  • Modulation of membrane traffic by mechanical stimuli.

    Gerard Apodaca

  • Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.

    Prasad Acharya;Jonathan Beckel;Wily G. Ruiz;Edward Wang

  • ATP and purinergic receptor-dependent membrane traffic in bladder umbrella cells.

    Edward C.Y. Wang;Jey-Myung Lee;Wily G. Ruiz;Elena M. Balestreire

  • β-Adrenoceptor Agonists Stimulate Endothelial Nitric Oxide Synthase in Rat Urinary Bladder Urothelial Cells

    Lori A. Birder;Michele L. Nealen;Susanna Kiss;William C. de Groat

  • Stretch-regulated Exocytosis/Endocytosis in Bladder Umbrella Cells

    Steven T. Truschel;Edward Wang;Wily G. Ruiz;Som-Ming Leung

  • Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells. Evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway.

    R Lindstedt;G Apodaca;S H Barondes;K E Mostov

  • Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells.

    Gerard Apodaca;James T. Rutka;Karyn Bouhana;Michael E. Berens

  • Na,K-ATPase activity is required for formation of tight junctions, desmosomes, and induction of polarity in epithelial cells.

    Sigrid A. Rajasekaran;Sigrid A. Rajasekaran;Lawrence G. Palmer;Sun Y. Moon;Alejandro Peralta Soler

  • Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation state.

    Yoram Altschuler;Carol L. Kinlough;Paul A. Poland;James B. Bruns

  • Bladder permeability barrier: recovery from selective injury of surface epithelial cells

    John Lavelle;Susan Meyers;Richard Ramage;Sheldon Bastacky

Frequent Co-Authors

Keith E. Mostov
Keith E. Mostov University of California, San Francisco
Mark L. Zeidel
Mark L. Zeidel Harvard Medical School
James R. Goldenring
James R. Goldenring Vanderbilt University
William C. de Groat
William C. de Groat University of Pittsburgh
James H. McKerrow
James H. McKerrow University of California, San Diego
Mark L. Rosenblum
Mark L. Rosenblum Henry Ford Health System
Linton M. Traub
Linton M. Traub University of Pittsburgh
Xiao Ming Yin
Xiao Ming Yin Indiana University
James R. Roppolo
James R. Roppolo University of Pittsburgh
Morgane Bomsel
Morgane Bomsel Université Paris Cité

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